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Epilepsy. Dr. Hardeep Singh Malhotra MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology, King George’s Medical University, Lucknow. MCQ-1. When do you label a “seizure” as “epilepsy”? Presence of family history >1 unprovoked seizure >1 provoked seizure
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Epilepsy Dr. Hardeep Singh Malhotra MD, DM,FIACM, MNAMS Associate Professor, Department of Neurology, King George’s Medical University, Lucknow
MCQ-1 • When do you label a “seizure” as “epilepsy”? • Presence of family history • >1 unprovoked seizure • >1 provoked seizure • >2 provoked seizures
MCQ-1 • When do you label a “seizure” as “epilepsy”? • Presence of family history • >1 unprovoked seizure • >1 provoked seizure • >2 provoked seizures
MCQ-2 • All of the following are excitatory neurotransmitters except: • AMPA • NMDA • GABA • Glutamate
MCQ-2 • All of the following are excitatory neurotransmitters except: • AMPA • NMDA • GABA • Glutamate
MCQ-3 • Which of the following abnormality is associated with ‘Generalized Epilepsy & Febrile Seizures plus’ syndrome? • Sodium channel mutations • Calcium channel mutations • Potassium channel mutations • Chloride channel mutations
MCQ-3 • Which of the following abnormality is associated with ‘Generalized Epilepsy & Febrile Seizures plus’ syndrome? • Sodium channel mutations • Calcium channel mutations • Potassium channel mutations • Chloride channel mutations
MCQ-4 • Which of the following abnormality is associated with ‘Juvenile Myoclonic Epilepsy’? • Sodium channel mutations • Calcium channel mutations • Potassium channel mutations • Chloride channel mutations
MCQ-4 • Which of the following abnormality is associated with ‘Juvenile Myoclonic Epilepsy’? • Sodium channel mutations • Calcium channel mutations • Potassium channel mutations • Chloride channel mutations
MCQ-5 • Which of the following abnormality is associated with ‘Temporal lobe epilepsy’? • Sodium channel mutations • Calcium channel mutations • Potassium channel mutations • Chloride channel mutations
MCQ-5 • Which of the following abnormality is associated with ‘Temporal lobe epilepsy’? • Sodium channel mutations • Calcium channel mutations • Potassium channel mutations • Chloride channel mutations
MCQ-6 • Pathophysiologically, which is the most important reason for the precipitation of seizure? • Increased Glutamate, increased GABA • Increased AMPA, increased GABA • Increased Glutamate, decreased GABA • Decreased Glutamate, increased GABA
MCQ-6 • Pathophysiologically, which is the most important reason for the precipitation of seizure? • Increased Glutamate, increased GABA • Increased AMPA, increased GABA • Increased Glutamate, decreased GABA • Decreased Glutamate, increased GABA
MCQ-7 • Clinically, the most relevant epilepsy classification system is: • ILAE 1985 • ILAE 1989 • ILAE 1991 • ILAE 2006
MCQ-7 • Clinically, the most relevant epilepsy classification system is: • ILAE 1985 • ILAE 1989 • ILAE 1991 • ILAE 2006
MCQ-8 • Which of the following is not a localization-related epilepsy? • Benign childhood epilepsy with centrotemporal spikes • Juvenile myoclonic epilepsy • Childhood epilepsy with occipital paroxysms • Primary reading epilepsy
MCQ-8 • Which of the following is not a localization-related epilepsy? • Benign childhood epilepsy with centrotemporal spikes • Juvenile myoclonic epilepsy • Childhood epilepsy with occipital paroxysms • Primary reading epilepsy
MCQ-9 • Which of the following is not an idiopathic generalized epilepsy? • Juvenile absence epilepsy • Epilepsy with grand mal seizures on awakening • Childhood absence epilepsy • Lennox-Gastaut syndrome
MCQ-9 • Which of the following is not an idiopathic generalized epilepsy? • Juvenile absence epilepsy • Epilepsy with grand mal seizures on awakening • Childhood absence epilepsy • Lennox-Gastaut syndrome
MCQ-10 • Which is the most important differential diagnosis of ‘first seizure’? • Migraine without aura • Abdominal migraine • Syncope • Migraine with aura
MCQ-10 • Which is the most important differential diagnosis of ‘first seizure’? • Migraine without aura • Abdominal migraine • Syncope • Migraine with aura