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Dr. Hardeep Singh Malhotra MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

Epilepsy. Dr. Hardeep Singh Malhotra MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology, King George’s Medical University, Lucknow. MCQ-1. When do you label a “seizure” as “epilepsy”? Presence of family history >1 unprovoked seizure >1 provoked seizure

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Dr. Hardeep Singh Malhotra MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

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  1. Epilepsy Dr. Hardeep Singh Malhotra MD, DM,FIACM, MNAMS Associate Professor, Department of Neurology, King George’s Medical University, Lucknow

  2. MCQ-1 • When do you label a “seizure” as “epilepsy”? • Presence of family history • >1 unprovoked seizure • >1 provoked seizure • >2 provoked seizures

  3. MCQ-1 • When do you label a “seizure” as “epilepsy”? • Presence of family history • >1 unprovoked seizure • >1 provoked seizure • >2 provoked seizures

  4. MCQ-2 • All of the following are excitatory neurotransmitters except: • AMPA • NMDA • GABA • Glutamate

  5. MCQ-2 • All of the following are excitatory neurotransmitters except: • AMPA • NMDA • GABA • Glutamate

  6. MCQ-3 • Which of the following abnormality is associated with ‘Generalized Epilepsy & Febrile Seizures plus’ syndrome? • Sodium channel mutations • Calcium channel mutations • Potassium channel mutations • Chloride channel mutations

  7. MCQ-3 • Which of the following abnormality is associated with ‘Generalized Epilepsy & Febrile Seizures plus’ syndrome? • Sodium channel mutations • Calcium channel mutations • Potassium channel mutations • Chloride channel mutations

  8. MCQ-4 • Which of the following abnormality is associated with ‘Juvenile Myoclonic Epilepsy’? • Sodium channel mutations • Calcium channel mutations • Potassium channel mutations • Chloride channel mutations

  9. MCQ-4 • Which of the following abnormality is associated with ‘Juvenile Myoclonic Epilepsy’? • Sodium channel mutations • Calcium channel mutations • Potassium channel mutations • Chloride channel mutations

  10. MCQ-5 • Which of the following abnormality is associated with ‘Temporal lobe epilepsy’? • Sodium channel mutations • Calcium channel mutations • Potassium channel mutations • Chloride channel mutations

  11. MCQ-5 • Which of the following abnormality is associated with ‘Temporal lobe epilepsy’? • Sodium channel mutations • Calcium channel mutations • Potassium channel mutations • Chloride channel mutations

  12. MCQ-6 • Pathophysiologically, which is the most important reason for the precipitation of seizure? • Increased Glutamate, increased GABA • Increased AMPA, increased GABA • Increased Glutamate, decreased GABA • Decreased Glutamate, increased GABA

  13. MCQ-6 • Pathophysiologically, which is the most important reason for the precipitation of seizure? • Increased Glutamate, increased GABA • Increased AMPA, increased GABA • Increased Glutamate, decreased GABA • Decreased Glutamate, increased GABA

  14. MCQ-7 • Clinically, the most relevant epilepsy classification system is: • ILAE 1985 • ILAE 1989 • ILAE 1991 • ILAE 2006

  15. MCQ-7 • Clinically, the most relevant epilepsy classification system is: • ILAE 1985 • ILAE 1989 • ILAE 1991 • ILAE 2006

  16. MCQ-8 • Which of the following is not a localization-related epilepsy? • Benign childhood epilepsy with centrotemporal spikes • Juvenile myoclonic epilepsy • Childhood epilepsy with occipital paroxysms • Primary reading epilepsy

  17. MCQ-8 • Which of the following is not a localization-related epilepsy? • Benign childhood epilepsy with centrotemporal spikes • Juvenile myoclonic epilepsy • Childhood epilepsy with occipital paroxysms • Primary reading epilepsy

  18. MCQ-9 • Which of the following is not an idiopathic generalized epilepsy? • Juvenile absence epilepsy • Epilepsy with grand mal seizures on awakening • Childhood absence epilepsy • Lennox-Gastaut syndrome

  19. MCQ-9 • Which of the following is not an idiopathic generalized epilepsy? • Juvenile absence epilepsy • Epilepsy with grand mal seizures on awakening • Childhood absence epilepsy • Lennox-Gastaut syndrome

  20. MCQ-10 • Which is the most important differential diagnosis of ‘first seizure’? • Migraine without aura • Abdominal migraine • Syncope • Migraine with aura

  21. MCQ-10 • Which is the most important differential diagnosis of ‘first seizure’? • Migraine without aura • Abdominal migraine • Syncope • Migraine with aura

  22. Thank you

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