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X chromosome instability in females or males of different genotypes. Sex genotype N° of metaphases nX nX+X nX-X nX+derX. female parp -1 +/+ ; parp -2 -/- 30 29 0 1 0.
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X chromosome instability in females or males of different genotypes Sex genotype N° of metaphases nX nX+X nX-X nX+derX female parp-1+/+ ; parp-2 -/- 30 29 0 1 0 female parp-1 -/- ; parp-2 +/+ 21 21 0 0 0 male parp-1 +/- ; parp-2 -/- 35 35 0 0 0 female parp-1 +/- ; parp-2 -/- 132 66 19 33 14 nX= metaphases with normal number of X chromosomes: XX for females and X for males Ménissier - de Murcia et al. 2003, EMBO J. 22, 2255