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Danilo Andrea Zanin

Benchmark of the 4D Treatment Planning at PSI. Danilo Andrea Zanin. 1. Danilo Andrea Zanin, June 2010. y z x. y z x. motion file time displacement 1s Δ x Δ y Δ z 2s Δ x Δ y Δ z 3s Δ x Δ y Δ z 4s Δ x Δ y Δ z.

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Danilo Andrea Zanin

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  1. Benchmark of the 4D Treatment Planning at PSI Danilo Andrea Zanin 1 Danilo Andrea Zanin, June 2010

  2. y z x y z x motion file timedisplacement 1s ΔxΔyΔz 2s ΔxΔyΔz 3s ΔxΔyΔz 4s ΔxΔyΔz ... motion file timedisplacement 1s ΔxΔyΔz 2s ΔxΔyΔz 3s ΔxΔyΔz 4s ΔxΔyΔz ... ... 4s ... 4s 4D Treatment Planning: Version 1 Antje-Christin Knopf, May 2010 Body moves rigidly 2 Antje-Christin Knopf, May 2010

  3. z z y y x x 1s motion map 1s motion map ... 4s ... 4s 2s motion map 2s motion map 3s motion map 3s motion map 4s motion map 4s motion map 1s motion map 1s motion map ... 4s ... 4s 2s motion map 2s motion map 3s motion map 3s motion map 4s motion map 4s motion map • 4D Treatment Planning: Version 2 • Antje-Christin Knopf, May 2010 • Body described with voxels • It will take into account • rigid/non-rigid • amplitude • period • Phase Motion divided in steps  Motion matrices Third version  Varying densities z z y y x x 3 Antje-Christin Knopf, May 2010

  4. Motivation • Control the rigid motion • Benchmark the implementations for the non rigid motion 4

  5. Motion Matrices • Defined in the gantry coords system: s,t,u • Divide the motion in txt-file steps  Generated with MatLab 5

  6. Motion types • Fixed body • Instant Motion  The body is misplaced • Continuous Motion  Natural motions 6

  7. Instant motion in the beam direction (s) and in orthogonal to it (t, u)‏ • Motion along “s” will not influence the calculated dose  only air change! • Motion orthogonal to “s” will move the calculated dose in the opposite direction  new tissue will be exposed to the pencil beam. 7

  8. Summary of the instant motion in s-direction 8

  9. Instant motion in u-direction of 3 cm instant motion of 3 cm uChange_150610_3 Reference 9

  10. Summary of the instant motion in u-direction 3 cm as upper limit 10

  11. Constant motion • Unidirectional Motion • Sinusoidal Motion  Constant motion in one direction will spread the dose but less than the instant one 11

  12. Constant motion in u-dir. of 0.2 cm  2 cm Constant motion of 0.2 cm uChange_170610_m1 Instant motion of 2cm uChange_110610_10 12

  13. Sinusoidal motion in u-dir. of 1 cm  +3/-3cm Sinusoidal motion of 1 cm uSway_170610_5 Reference 13

  14. Summary of constant and sinusoidal motions 14

  15. Instant union/division • AIR gap VS Tissue superposition • AIR gap: less tissue exposed dose calculation reduced • Tissue superposition: more tissue exposeddose calculation enhanced 15

  16. Instant union/division in u-direction of 3 cm Frontal view Instant division of 3 cm uDevide_160610_3 Instant union of 3 cm uUnion_160610_3 Sagittal view 16

  17. Instant union/division in u-direction of 3 cm 17

  18. Instant union/division in s-direction of 3 cm Instant union of 3 cm sDevide_170610_1 Instant division of 3 cm sDevide_170610_2  No changes observed! 18

  19. Other Special Motions • Instant slide on an plane • Instant explosion / implosion • Pulse 19

  20. Instant slide in t-direction of 3 cm Transaxial view Instant slide of +3/-3 cm sSlide_170610_1 Reference Sagittal view 20

  21. 4D treatment planning Instant implosion in all-direction of 3 cm Instant explosion of 3 cm explode_210610_2 Reference 21

  22. 4D treatment planning – Instant explosion in all-direction of 3 cm Instant explosion in all-direction of 3 cm Instant explosion of 3 cm explode_210610_1 Reference 22

  23. Conclusions • Good response to rigid body motions • Good adaptability to non rigid body motions • Displacement threshold (3 cm) • Do not care about motions in depth • Do not care about density changes 23

  24. Thanks to everybody! 24

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  26. Relation between coordinates systems Gantry coords syst. Patient coords syst. 26

  27. References for all the results • All motion matrices are stored in: “/asm/pdata/EXP/AKT030/Motionvectors_DZ/matlab” • All the dose are calculated with: “/asm/apps/dev/ptplan04/WIDGETS/DOSE_FIELD/4d/DZ/script_M1.sh” and are saved in:“/asm/pdata/EXP/AKT030/Zanin  in the same directory can be found also a file: “info.txt” containing a short description of the different calculated dose 27

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