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TxLOR.ORG

Texas Learning Object Repository. TxLOR.ORG. Digital library of assets and objects Approval system for UT health institutions and Texas public higher education institutions. What is TxLOR?. Faculty and staff members at UT health and Texas public higher education institutions

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TxLOR.ORG

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  1. Texas Learning Object Repository TxLOR.ORG

  2. Digital library of assets and objects Approval system for UT health institutions and Texas public higher education institutions What is TxLOR?

  3. Faculty and staff members at UT health and Texas public higher education institutions Only one requirement: institutional agreement to create workflow manager Who may contribute to TxLOR?

  4. Have your Provost or VPAA contact us: Support@TxLOR.org How do I contribute to txlor?

  5. Anyone may view unless content is restricted Anyone may download (and modify) if allowed under Creative Commons license specified by author Who Can Access TxLOR?

  6. Go to http://www.txlor.org Select Search Enter keyword(s) and other delimiters such as date(s) How do I search txlor?

  7. Click filename to view Click arrow to download Copy URI to link How do I use txlor?

  8. Sample Academic Asset

  9. Sample Health Object Vicki S. Freeman, Ph.D., FACB Laboratory Testing for Iron

  10. Discuss the common method of analysis for iron. Discuss the determination of TIBC and the calculation of UIBC and % Saturation. Objectives

  11. Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 c c c c c c c c c c Total Iron Binding Capacity • 1 µmol of transferrin binds 2 µmol of iron Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 = Transferrin

  12. Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 c c c c c c c c c c % Saturation • The ratio of serum iron to iron-binding capacity Fe+3 Fe+3 Fe+3 9 transferrin molecules = 18 sites 13 Fe molecules = 72% Saturation = Transferrin

  13. c c c c c c Testing for Iron Color Change is measured Transferrin transports iron in blood stream (from intestine to cells) “Alkaline Rain” changes ferrous iron to ferric iron “Acid Rain” removes iron from transferrin protein Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+2 Fe+2 Fe+2 Fe+2 Fe+2 Fe+2 Fe+2 Fe+2 Fe+2 Fe+2 Fe+2 Fe+2 acid Fe3+ + Transferrin Fe3+ + apotransferrin Reducing Agents Fe 3+ + 2Fe2+ Complexing chromogen Fe 2+ + Colored complex

  14. Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 c c c c c c c c c Total Iron Binding Capacity Add excess iron Bind Fe+3 to free transferrin binding sites Remove Fe+3 left in serum - measure per iron method on previous slide Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3

  15. Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 c c c c c c c c c Unsaturated Iron Binding Capacity Add 17 molecules of iron Bind Fe+3 to free transferrin binding sites Measure Fe+3 left in serum - subtract from original 17 molecules Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3 Fe+3

  16. Iron is transported by _______________. The main storage form of iron is __________. The purpose of hydroxyamine in the iron procedure is to __________Fe+3 to _______. A patient has a serum Fe of 100 mcq/dl and a TIBC of 225 mcq/dl. Calculate the UIBC and % saturation. Questions to think about

  17. TxLOR.org TxLOR@utsa.edu Questions?

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