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HEMOPARASITES. Hemoparasites. Feline Hemotropic Mycoplasma: Formerly known as Hemobartonella Felis Parasites that attach to the outside of the RBC and result in hemolytic anemia Small, gram-negative bacteria that lack a cell wall and infect a variety of mammalian species
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Hemoparasites • Feline Hemotropic Mycoplasma: • Formerly known as HemobartonellaFelis • Parasites that attach to the outside of the RBC and result in hemolytic anemia • Small, gram-negative bacteria that lack a cell wall and infect a variety of mammalian species • Three types have been identified, hemofelis sp., candidatushemominutumand candidatusturicensis
Hemoparasites • FHM: • 14.5% healthy client owned cats are + • 28% sick cats are positive • Risk factors: access to outdoors, fleas, male gender, <4-6 years of age, summer months, FELV+, cat bite abscesses • Transmission through fleas, possibly ticks and lice • Biting, blood transfusion
Hemoparasites • FHM: • Regenerative anemia, unless concurrent with FELV • Every anemic cat should be evaluated for FHM microscopically • Form chains or rings across the surface of the RBC membrane • Can be mistaken for stain precipitate, Howell-Jolly bodies, basophilic stippling, reticulocytes, etc. • Should be confirmed with further testing for organism
Hemoparasites • Cytauxzoonfelis: serious, often fatal, protozoal disease affecting domestic cats in the south central and southeastern portions of the United States • The natural reservoir host of C. felis is the North American bobcat • Ticks are believed to be the natural vector for this organism • Erythrocytic and leukocytic
Hemoparasites • CF: parasites may appear as round to oval "signet rings" , bipolar, oval, "safety pin" forms, tetrad forms; or anaplasmoid round "dots“ • May have a small, peripherally-located nucleus that stains dark red to purple with off- white to light blue cytoplasm when using Giemsa stain. • Small amount of parasites on RBCs, the majority are found on fine needle aspirates of spleen, lymph nodes and bone marrow
Hemoparasites • Babesiacanis, gibsonii: • Protozoalorganisms that parasitize erythrocytes, causing anemia in the host • Transmission- tick vector, blood to blood contact (bite wounds) • Babesiacanis: teardrop shape in RBC, greyhounds • Babesiagibsonii: ring or coccoid object in RBC, pit bulls • Causes hemolytic anemia
Hemoparasites Babesiagibsonii Babesiacanis
Hemoparasites • Anaplasmamarginale: • Formerly Ehrlichiasp. • Tick vector, blood transfusion • Bacteria-like, causes severs hemolytic anemia
Hemoparasites • Microfilaria: • Dirofilariaimmitis • Vector is the mosquito • Tapered ends • Indicates the presence of adult female worms • Can cause damage to RBCs in vessel