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Lecture 19 – Epigenomics – Plants. BIOL 5190/6190 Cellular & Molecular Singal Transduction Prepared by Bob Locy Last modified -13F. Epigenetics – Stable, but expression-related changes in gene function. Methylation of DNA & Histones is involved in epigenetic transcriptional regulation
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Lecture19–Epigenomics – Plants BIOL 5190/6190 Cellular & Molecular Singal Transduction Prepared by Bob Locy Last modified -13F
Epigenetics – Stable, but expression-related changes in gene function • Methylation of DNA & Histones is involved in epigenetic transcriptional regulation • Correlation between DNA methylation and histone modification • Correlation between gene expression changes and DNA Methylation • Transposable elements are regulated by DNA Methylation • Correlation between DNA Methylation and TE transposition • How is DNA methylation mediated? • Enzymology known • Transposable elements part of repeat-associated/heterochromatic DNA in the genome • Repeat associated DNA methylation controls “transposase” function that mediates transposition, and thus, epigenetic “inheritance”
Plant Biotic and Abiotic Stress Responses • Old time work • Epigenetic stuff • State of the Art
Epigenetic Regulation of Transcription and Transposition Bucher et al., (2012) Current Opinion in Plant Biology 15 (5): 503-510
Stress Regulated Epigenenic Gene Regulation Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
Proposed model for Epigenetic Control of TE-host coevolution Bucher et al., (2012) Current Opinion in Plant Biology 15 (5): 503-510
Transducers Second Messengers I J.R., and Pikaard, C.S. 2011. Nature Reviews Molecular Cell Biology 12:483–492.
CSB Fig 02:01 Cell signalling pathways J.R., and Pikaard, C.S. 2011. Nature Reviews Molecular Cell Biology 12:483–492.