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what is Glioblastoma Multiforme brain tumor

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what is Glioblastoma Multiforme brain tumor

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  1. DelveInsight Business Research USA: 304 S. Jones Blvd #2432, Las Vegas NV 89107 India: Sector-7, Dwarka, New Delhi-110077, India USA: +1(919)321-6187 India: +91-11-45689769,+91-9650213330

  2. What is GlioblastomaMultiforme brain tumor? GlioblastomaMultiforme (also called GBM) are malignant Grade IV tumors, where a large portion of tumor cells reproduce and divide at any given time. The tumor is predominantly made up of abnormal astrocytic cells, which also contain a mixture of different cell types (including blood vessels) and areas of dead cells (necrosis).

  3. Glioblastomas are infiltrative and invade into nearby regions of the brain. They can also sometimes spread to the opposite side of the brain through connection fibers (corpus callosum). The symptoms of GBM vary depending on the location of the brain tumor such as persistent headaches, double or blurred vision, vomiting, loss of appetite, changes in mood and personality, changes in ability to think and learn, new onset of seizures, speech difficulty of gradual onset, etc. The exact underlying cause of GBM is unknown.

  4. Some cases may develop from existing, low-grade astrocytomas (malignant transformation) or they may occur without any evidence of a previous tumor (de novo). Researchers speculate that genetic and immunologic abnormalities, environmental factors (e.g., exposure to ultraviolet rays, certain chemicals, ionizing radiation), diet, stress, and/or other factors may play contributing roles in causing specific types of cancer.

  5. However, no conclusive evidence has thus far demonstrated a direct causal relationship between these factors and the induction of GBM tumors in human patients. The diagnosis of GBM mainly includes use of neurological examinations, imaging tests and excising a sample of tissue for testing, i.e, biopsy.The mainstay of treatment for GBM is surgery, followed by radiation and chemotherapy. The primary objective of surgery is to remove as much of the tumor as possible without injuring the surrounding normal brain tissue needed for normal neurological function (such as motor skills, the ability to speak and walk, etc.).

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