Advanced Infertility Treatment|ICSI,IVF,Egg Donation|Yashodaivfcentre

1. Advanced Infertility Treatment Advanced Infertility Treatment Involves Following Tests: IUI (Intrauterine Insemination) Intrauterine insemination or commonly known artificial insemination involves the preparation of a highly concentrated sperm sample to be placed into the uterus at the time of ovulation. Depending on the infertility cause, IUI can be coordinated with your normal cycle or done in conjunction with ovulation induction medications. Each cycle is carefully monitored through office visits, ultrasound and blood work. The cost is relatively low for IUI, and it is usually the first step in low-tech treatment. The IUI is performed by threading a very thin flexible catheter through the cervix and injecting washed sperm directly into the uterus. The procedure is similar to a Pap smear exam and can be done in the comfort of our center. The patient is encouraged to rest for a few minutes and then given instructions to contact our center if she does not start a period 14 days after insemination, at which point, we will test for pregnancy. IVF (In Vitro Fertilization) The union of the ovum (egg) and the sperm outside the woman's body is In- vitro fertilization (IVF). This is the first step in this process to regulate fertility drugs to the woman for ensuring the development of multiple eggs for fertilization. We then retrieve her eggs through an ultrasound-guided surgical procedure in our in-office surgical suite under anesthesia. Next, we fertilize the eggs in our lab, and we culture (grow) resulting embryos until they reach the blastocyst stage. Once embryos reach the blastocyst stage (a more mature stage of embryo growth), we transfer a minimum number – one to two, depending on each patient –to the woman’s uterus using a non-surgical, ultrasound-guided procedure called embryo transfer. Non-transferred embryos may be cryopreserved (frozen) for future use. 1 http://www.yashodaivfcentre.com/intracytoplasmic-sperm-injection-in-mumbai/

2. ICSI (Intra Cytoplasmic Sperm Injection) Since long time, fertility centers around the world have crawled to master the technique of intracytoplasmic sperm injection (ICSI), a breakthrough procedure that has mutinied treatment for male factor infertility and boosted national IVF success rates significantly. ICSI’s innovation lies in the ability of specialists to inject a single sperm directly into an egg. Until ICSI, low sperm counts and sperm with poor movement or shape posed barriers to fertility since the sperm possessed a significantly reduced potential to fertilize eggs. Today, ICSI coupled with IVF, offers childless couples significantly higher chances at fertilization. Live birth rates for couples requiring ICSI are similar to rates for couples not requiring ICSI, assuming the woman is of similar age. Which Couples Need IVF with ICSI? Indications for IVF and ICSI are: 1. Severely low sperm count (usually less than 5 million sperm/ml) 2. Severely low motility (usually less than 20 percent even with normal sperm counts) 3. Normal percent motility but with a poor motility grade (grade is how well the sperm swim) 4. Severely abnormal morphology (sperm shape) 5. Failed or poor fertilization in a previous IVF attempt PESA / TESA In some individuals, spermatozoa may not be present in the ejaculate. This condition is called Azoospermia. This can be either due to problems in sperm production itself or due to obstruction to the flow of semen during ejaculation. Reproductive tract obstruction can be acquired - as a result of infection, trauma, iatrogenic injury which can occur during bladder neck, pelvic, abdominal or inguino-scrotal surgery. Congenital anomalies may be relatively uncommon in the general population, but can occur in up to 2 percent of infertile men. Two techniques - Epididymal sperm retrieval & micromanipulation have revolutionized treatment of male infertility in the past decade. 2 http://www.yashodaivfcentre.com/intracytoplasmic-sperm-injection-in-mumbai/

3. 1.PESA PESA or Percutaneous Epididymal Sperm Aspiration (PESA), does not require a surgical incision. A small needle is passed directly into the head of the epididymis through the scrotal skin and fluid is aspirated. The embryologist retrieves the sperm cells from the fluid and prepares them for ICSI. 2.TESA TESA or testicular sperm aspiration is performed by inserting a needle in the testis and aspirating fluid and tissue with negative pressure. The aspirated tissue is then processed in the embryology laboratory and the sperm cells extracted are used for ICSI. Laser Assisted Hatching Laser-assisted hatching is one of several methods available to help an embryo hatch from a fertilized egg’s protective shell and attach to the uterus. The technology is helpful in cases where the shell of a fertilized egg is thicker or harder than normal. Laser-assisted hatching can greatly increase a woman’s chances of becoming pregnant.At the YashodaIVFcentre, we offer the latest state-of-the-art technology for zona hatching using laser-assisted hatching – a gentle and safe way to weaken part of the zona pellucida. Laser-assisted hatching features the creation of a small hole in the zona of an embryo using laser technology. This allows the embryo to hatch more easily, therefore increasing the chance of implantation. Laser-assisted hatching is performed just before an embryo transfer procedure. There is no evidence that laser-assisted hatching is harmful to embryos, and recent research shows that women who have undergone repeated IVF treatments without success significantly increase their chances of pregnancy with assisted hatching. 3 http://www.yashodaivfcentre.com/intracytoplasmic-sperm-injection-in-mumbai/

4. Blastocyst Culture YashodaIVFcentre has a long history of growing embryos to the blastocyst stage, the preferred industry standard for embryo culturing. We are the only center in Navi Mumbai, India that routinely transfers embryos at the blastocyst stage, with more than 95 percent of all embryo transfers performed using this technology. This is possible due to our expert Reproductive Studies Lab, which has perfected the culture medium used to grow embryos to the blastocyst stage. The advantages of blastocyst transfer to patients are higher pregnancy rates and fewer embryos transferred to the uterus per IVF cycle. Transferring fewer embryos to the uterus results in lower rates of twins and high order multiple pregnancies (triplets and above). Embryo Freezing Patients who undergo in vitro fertilization and have more embryos than needed for transfer may choose for those embryos to be cryopreserved (frozen). Embryo cryopreservation offers additional opportunities for pregnancy at a later date without the time and expense of egg retrieval. Frozen Embryo Transfer (FET) Frozen embryo transfer is a procedure, using embryos that were not transferred during a fresh in vitro fertilization (IVF) cycle but were instead frozen, or cryopreserved, for later use. While we now routinely freeze embryos at the blastocyst stage, previously, embryos were frozen at an earlier stage of development. Our embryologist will thaw and culture such embryos to the blastocyst stage – our quality standard for achieving the highest likelihood of pregnancy. Meanwhile, one of our physicians will meet with the patient to begin preparation of the uterine lining (endometrium), which will be synchronized with the development stage of the thawed embryos. The patient will take minimal Estrogen doses to begin building her uterine lining and progesterone support, to be continued until early pregnancy confirmation. 4 http://www.yashodaivfcentre.com/intracytoplasmic-sperm-injection-in-mumbai/

5. Embryo Donation YashodaIVFcentre is one of only a few centers to offer an ongoing and highly successful embryo donation program. Characteristics of successful embryo donation programs include: high IVF live birth rates, a high quality embryo cryopreservation (freezing) program, and the ability to generate multiple embryos from each IVF or donor egg cycle. More importantly, a center must have loving and generous couples who, when their family is complete, are willing to offer their frozen embryos for donation to a couple, either known or anonymous. YashodaIVFcentre is blessed to have all of the above. Our live birth rate per transfer in our egg donation program has consistently been greater than 70 percent. Consequently, couples often find they have more frozen embryos than they need for their own families and decide to offer a wonderful gift to other couples – their embryos. To run every ART(Assisted reproductive technology) treatment successfully, we at Yashoda Hospital perform a very detailed investigation of both the partners with a detailed medical history and detailed examination of the couple, only then the most suitable treatment option is suggested. Why choose YashodaIVFcentre? YashodaIVFcentre offer a well-established IVF program that has been home to many area firsts, including blastocyst transfer, fertility preservation via egg freezing, preimplantation genetic diagnosis and screening,intracytoplasmic sperm injection in mumbai and Egg donation in mumbai. We continuously research and develop a wide range of technologies to provide our patients the highest possibility of having a baby, as evidenced by our success rates. Renowned doctors equipped with expertise Best equipment Best technology Popular destination for IVF treatment 5 http://www.yashodaivfcentre.com/intracytoplasmic-sperm-injection-in-mumbai/

6. Gives basic and advanced fertility treatment all under one roof Cost effective Offers counseling and treatment to the couple so that the patients are at ease Ray of hope to childless couple We promise: Sincerity and honesty at all times Fairness and absolute transparency Good communication Clarity in all financial matters Professional advanced medical care To look after yours and the donors/surrogates interests at all times All required services under one roof 6 http://www.yashodaivfcentre.com/intracytoplasmic-sperm-injection-in-mumbai/