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NEUR 4850

NEUR 4850. Advanced Techniques in Cognitive Neuroscience. Course Structure. Intentionally loose structure – we’ll create this course as we go along and explore different approaches to EEG You will function as if you are students in my lab. Course Structure. Grading 30% class participation

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NEUR 4850

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  1. NEUR 4850 Advanced Techniques in Cognitive Neuroscience

  2. Course Structure • Intentionally loose structure – we’ll create this course as we go along and explore different approaches to EEG • You will function as if you are students in my lab

  3. Course Structure • Grading • 30% class participation • 30% midterm exam • 40% project

  4. Rough Timeline

  5. Course Structure • The Project: • Design and carry out a simple “demonstration” (not experiment) • Using SIMPLE gadgets and gizmos that you find around the lab • A button box to record participant’s input • A Simple computer program that blinks boxes on the screen • Paper, Pencil, etc. • Random stuff…

  6. Electroencephalography and the Event-Related Potential • 1929 – first measurement of brain electrical activity from scalp electrodes (Berger, 1929) • Believed to be artifactual and/or of no significance • Currently PubMed search for “EEG” in keywords returns 107,088 hits • That’s about 3 ½ papers per day

  7. Electroencephalography and the Event-Related Potential Voltage Time • Place an electrode on the scalp and another one somewhere else (non-cephalic ground) • Amplify the signal to record the voltage difference across these electrodes • Keep a running measurement of how that voltage changes over time • This is the EEG

  8. From EEG to ERP • The EEG is characterized by ongoing “oscillations” that (presumably) reflect aspects of the underlying neural activity

  9. From EEG to ERP • The EEG is characterized by ongoing “oscillations” that (presumably) reflect aspects of the underlying neural activity • Discrete events such as stimuli don’t usually “show up” in the EEG wave • Substantial signal processing is necessary to reveal the “signal” from the “noise” • Much of the “post-processing” of scalp recorded EEG is directly related to handling intra-cranial EEG

  10. CCBN Dense-Array EEG Data Files Event Triggers Stimuli Raw EEG .raw MatLab Fieldtrip BrainVoyager SPSS -EEG spectral analysis - MRI coregistration Netstation – records EEG and event triggers .sfp BESA -post-processing -ERP averaging -voltage maps -source imaging Digamize –records electrode locations MANUSCRIPT

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