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HIV infection(AIDS) Dr. Yingguo Ding Dept. of Dermatology First Affiliated Hospital

Sexually transmitted disease. HIV infection(AIDS) Dr. Yingguo Ding Dept. of Dermatology First Affiliated Hospital. - Cutaneous manifestations and management. Pathogenesis. Human immunodeficiency virus (HIV) I type &II type

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HIV infection(AIDS) Dr. Yingguo Ding Dept. of Dermatology First Affiliated Hospital

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  1. Sexually transmitted disease HIV infection(AIDS)Dr. Yingguo DingDept. of DermatologyFirst Affiliated Hospital - Cutaneous manifestations and management

  2. Pathogenesis • Human immunodeficiency virus (HIV) I type &II type • isolated from blood, serum, genital secretions, breast milk, cerebrospinal fluid, urine, saliva and lacrimal fluid. • Main infection routes • Sexual activity • Blood infection(blood products transfusion, sharing of needles for drugs, needle stick accidents) • Mother-to-child infection

  3. Mechanism

  4. Cutaneous manifestations of AIDS - three categories • Infection • Tumor • Non-infectious severe,atypical,bigotry

  5. Infection： 1. Oral hairy leukoplakia (OHL)：  20％ Early specific sign EBV correlating Candida (+)

  6. 2.Viruse infections： - Herpes zoster/Herpes simplex - CA：giant - Warts - CMV

  7. 3.Fungi infections： - Tinea - Candidiasis - Cryptococcosis 2％9％，multiformic，

  8. Cryptococcosis

  9. 4.Bacteria infections: - folliculitis,impetigo… - TB：warty tuberculosis

  10. Tumor: 1.Kaposi’s sarcoma  30％ risk generalized progressive painful systemic

  11. 2.non-Hodgkin's lymphoma(NHL): 4％～10％ 3.Other：Mycosis Fungoides(MF)、squamous cell carcinoma(SCC)、basal cell carcinoma(BCC)、malignant melanoma(MM)…

  12. Non-infectious 1.Seborrheic dermatitis： 70％～80％, early stage 2.Psoriasis: ～5％，first sign, mark of poor prognosis 3.hair abnormalities: alopecia,white hair,prolonged eyelashes… 4.Drug eruptions

  13. Ichthyosiform lesions

  14. There is no cure or vaccine for HIV yet. Important：epidemic prevention

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