Working Muscles!

1. Working Muscles!

2. Still confused about gross muscles? Go to http://academic.kellogg.cc.mi.us/herbrandsonc/bio201_McKinley/f10-3_formation_structu_c.jpg for muscle cell structures Go to http://www.uoguelph.ca/zoology/devobio/210labs/sketchmuscle1.html

3. Review of Skeletal Muscle MicroAnatomy and Sliding Filament Theory • Go to http://www.brookscole.com/chemistry_d/templates/student_resources/shared_resources/animations/muscles/muscles.html • Can you complete the quizzes in one try?

4. Terminology will getcha everytime! That darn terminology – you just can’t avoid it. If you can’t figure out a Z line from a sarcomere, then this is the site for you! Go to http://highered.mcgraw-hill.com/olc/dl/120104/bio_b.swf to help you with terminology – and a lot more! Scroll to the bottom.

5. Muscles, myofibrils, actin and myosin, OH MY! Here is a photo showing the relationship of the various parts of the myofilaments

6. Mechanics, Cross-Bridges and Power Cycles – not more! Ever wanted to be in the middle of what’s happening? This animation will take you INSIDE the actin and myosin crossbridges to see how ATP helps actin move with the help of myosin! Go to http://lessons.harveyproject.org/development/muscle/power.htmland click on the Shockwave Icon to view the animation. NOTE: this takes time to load!

7. Muscle Contraction Nerves at the neuromuscular junction coordinate the overall movement of the gross muscle, such as a bicep. Go to http://www.physioviva.com/movies/vertebrate_innervation/index.html to view how muscles move with a variety of nerves ennervating the muscle and what happens when they all fire at once! Note the distance the muscle contracts for each “color” neuron. Why is it significant for all the neurons to fire simultaneously for movement?

8. Contract that muscle! View the animation to help you get a greater connection between muscle contractions, cross-bridging and sarcomere shortening. Go to http://highered.mcgraw-hill.com/sites/0072437316/student_view0/chapter42/animations.html# and click on the “Sarcomere Shortening” link.

9. Action, action, we want action! What is an action potential? How is it propagated? Should I care about this? Well, yeah, cuz yer doing it right now as you think! Go to http://www.blackwellpublishing.com/matthews/actionp.html and click on the button to see how continuous conduction works. For fun, click on the saltatory conduction and compare the two! Then, look at this clip http://www.dnatube.com/view_video2.php?viewkey=f21d69c91dddeefb792a&featuredesc= Interesting graphics, gives you an idea of what is happening on the outside of the nerve axon

10. So, how does an action potential occur? Funny you should mention that… go to http://www.blackwellpublishing.com/matthews/channel.html and watch what happens a couple of times. Green is Na+; orange is K+. Also Too abstract? Need more explanation? Go to your IAP CD, click on Nervous I System, Topics; then click on “Action Potential”. Take notes.

11. How nerves and muscles work to permit contraction • What happens at the neuromuscular junction http://highered.mcgraw-hill.com/sites/0072495855/student_view0/chapter10/animation__function_of_the_neuromuscular_junction__quiz_3_.html • Put it all together! http://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter9/animation__action_potentials_and_muscle_contraction.html

12. Muscle Twitch or “Fasciculations”(fas – sic –u- lay-shuns) The response of a motor unit to a single action potential is called a muscle twitch. Muscle twitch can be viewed when using an electromyogram. Go to http://lessons.harveyproject.org/development/muscle/twitch~1.htm (This takes a while to load so be patient) For this slide • view a muscle twitch in action and identify the three parts of a muscle twitch – the latent period, the period of contraction and the period of relaxation • Describe how multiple twitches result in tetanus

13. Incomplete tetanus results in shaky muscles

14. Shaky Muscles! • Muscles “shake” when a larger force is applied (you lift something heavier than the muscle is use to) causing incomplete tetanus!

15. Why don’t my muscles just keep going?

16. So what is a Charley Horse? Go to http://www.nlm.nih.gov/medlineplus/ency/article/002066.htm to answer this compelling question! Take notes on the information!

17. Virtual Muscle Lab • We will do this when you return! • Obtain a copy of the lab “ Skeletal Muscle Physiology: Computer Simulation” as well as a copy of the PhysioEx 7 CD and complete the lab.

18. White or Red? Muscle fibers come in two types – fast twitch or slow twitch. Use the sites below to help you learn more about these amazing fibers! • http://btc.montana.edu/olympics/physiology/mf01.html • Also go to http://webanatomy.net/anatomy/muscle3_notes.htm and go down to the chart on fast twitch, intermediate and slow twitch muscles!

19. Who says I’m Eccentric? Eccentric, concentric? So what! Hey, if you’re a skier, you better know! Go to http://btc.montana.edu/olympics/physiology/mf02.html to learn how skiers use eccentric and concentric muscles!

20. Let’s All Exercise!!! How does Isometric differ from Isotonic? Which is better for building muscles? Why?

21. Using your muscles! • Get the Move Those Muscles handout from Ms. P and follow the directions to identify Isometric Vs. Isotonic and Eccentric Vs. Concentric Muscles in a series of activities.

22. Put it All Together! • Way cool video! Go to http://www.dnatube.com/view_video2.php?viewkey=a4cc25076f3d868e1bdf&featuredesc= and observe the combination of nerve firing all the way to sliding filaments!

23. Botulism = Muscle ParalysisNo fun! Go to the CDC FAQs on Botulism and take notes on the answers to the questions! http://www.cdc.gov/nczved/dfbmd/disease_listing/botulism_gi.html Psssst – it’s a big deal!

24. What is botox and how does it work? Go to http://www.medicalnewstoday.com/articles/158647.php to learn more!

25. BATTLESHIP! Think you know everything there is to know about muscle metabolism, muscle fiber types and a bunch of other stuff. Go to http://lessons.harveyproject.org/development/muscle/fibtyp.swf and try to keep your battleship from getting sunk!