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Magnetic resonance imaging: basic principle. Qiujianfeng 邱建峰 jfqiu100@tsmc.edu.cn 13082777550. About me. Mri & the principle of medical imaging Sorry for my english Basic mri Mri ’ s application. 1 、 What’s the MRI?. ( N uclear ) M agnetic R esonance I maging MRI ( NMR CT ). MRI
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Magnetic resonance imaging:basic principle Qiujianfeng 邱建峰 jfqiu100@tsmc.edu.cn 13082777550
About me • Mri &the principle of medical imaging • Sorry for my english • Basic mri • Mri’s application
1、What’s the MRI? (Nuclear)Magnetic Resonance Imaging MRI(NMR CT) MRI NMR
NMR • Digital signal processing(1D) • Chemical analysis
MRI • imaging • Diagnosis the diseases
The discoverers of NMR 1952 Nobel Prize for Physics NMR Edward Mills Purcell 1912-1997 Felix Bloch 1905-1983 Stanford University MIT
The discoverers of MRI 2003 Nobel Prize in Physiology or Medicine MRI Lauterbur, 1929 Mansfied 1933
Paul C. Lauterbur – Prize Award Photo Sir Peter Mansfield – Prize Award Photo 10/6,2003
The Shameful Wrong that must be righted Bypassed by nobel Prize Damadian Show the relaxation times of tissue and tumor differed
Check in • Location to the mri center • Operating the computer • Waiting…… (a cup of tea) • Read the images
Pacemaker! No! • Key! no! • metal filling! no!
Coils around the body • Signal Source
Earphone • Ear plugs • 30-60 minuters • Repetitive knocking sounds • Caused by electric currents in gradient fields
4、The safety of mri • Non-ionizing radiation • Dangers of Ferromagnetic object near the MRI magnet
× • Claustrophobic Phobia fear of narrow space • Metal implants Pacemaker\dentures\bone screws…… • Pregnant women • Child × √ √
5.What’s the difference between the mri and other medical imaging technologies?
Conventional imaging projection imaging
MRI • Multi-dimension imaging(inclined plane ) • High quality soft tissue imaging • Non-ionizing radiation GE 3.0T mri scaner
Multimodality imaging T1 Contrast TE = 14 ms TR = 400 ms T2 Contrast TE = 100 ms TR = 1500 ms Proton Density TE = 14 ms TR = 1500 ms
Multi-dimension imaging T1 Contrast TE = 14 ms TR = 400 ms T2 Contrast TE = 100 ms TR = 1500 ms Proton Density TE = 14 ms TR = 1500 ms
Sagittal plane Coronal plane Axial plane
3D Fusion from CT and MR MR CT
Background knowledge Hydrogen atom 1H
Background knowledge hydrogen atoms In the main magnetic field
basic principle Magnetic Moment • H2O Hydrogen X 2 Oxygen X 1 Oxygen X 10
4.3 basic principle • E = B, 是具有量子取向的。因此 角也具有不同取值,对于氢核,具有两种趋向。
4.3 basic principle • 为使核磁矩在磁场中的势能发生变化(即使μ与B夹角θ变化),必须外施能量或吸收能量。这可借与静磁场B的方向相垂直的平面(x-y平面)内加上一个在时间上交变的磁场
4.3 basic principle • θ增加,势能增加,能量增量由外加交变磁场提供; • θ减小,势能减小,能量交给外加交变磁场。 • 仅当交变磁场角频率满足ω=γB=ω0时才发生此种能量交换。 • 此时μ与B1_ 绕z轴同步旋转 —〉核磁共振现象