40 likes | 163 Views
Validation of a 12-Gene Colon C ancer Recurrence Score ® in Stage II Colon C ancer P atients from CALGB 9581.
E N D
Validation of a 12-Gene Colon Cancer Recurrence Score®in Stage II Colon Cancer Patients from CALGB 9581 A.P. Venook1, D. Niedzwiecki2, M. Lopatin3, M. Lee3, P. N. Friedman4, W. Frankel5, K. Clark-Langone3, C. Yoshizawa3, C. Millward3, S. Shak3, R. M. Goldberg6, N. N. Mahmoud7, R. L. Schilsky4, M. M. Bertagnolli8 1. University of California, San Francisco, San Francisco, CA; 2. Duke University, Durham, NC; 3. Genomic Health, Redwood City, CA; 4. The University of Chicago, Chicago, IL; 5. The Ohio State University, Columbus, OH; 6. University of North Carolina at Chapel Hill, Chapel Hill, NC; 7. University of Pennsylvania, Philadelphia, PA; 8. Brigham and Women's Hospital, Boston, MA Venook AP, et al. ASCO 2011. Abstract 3518 (poster presentation).
CALGB 9581: A Unique Opportunity to Test the Oncotype DX® Assay in Low/Standard Risk Stage II Colon Cancer • Sampling design with 690 evaluable patients, including 162 recurrence events, representative of 1,672 stage II colon cancer patients from CALGB 9581 • A population where risk discrimination is challenging with conventional clinical and pathologic factors Venook AP, et al. ASCO 2011. Abstract 3518 (poster presentation).
CALGB 9581: Second Successful Prospectively-Designed Confirmation Study RS, Recurrence Score® Venook AP, et al. ASCO 2011. Abstract 3518 (poster presentation).
CALGB 9581: Improving the Ability to Discriminate High vs. Low Risk of Recurrence in Standard Risk Stage II Colon Cancer RS, Recurrence Score® Venook AP, et al. ASCO 2011. Abstract 3518 (poster presentation).