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Person-to-Person Microbial Diseases

Person-to-Person Microbial Diseases. Airborne Transmission Respiratory Infections Human Reservoir “Tough Microbes” 10,000 -100,000 bacteria per sneeze. Streptococcus. Streptococcus pyogenes S. pneumoniae Strep Throat. Other Strep Infections. Group A Strep -GAS  Hemolytic Strep.

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Person-to-Person Microbial Diseases

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  1. Person-to-Person Microbial Diseases • Airborne Transmission • Respiratory Infections • Human Reservoir • “Tough Microbes” • 10,000 -100,000 bacteria per sneeze

  2. Streptococcus • Streptococcus pyogenes • S. pneumoniae • Strep Throat

  3. Other Strep Infections • Group A Strep -GAS •  Hemolytic Strep. • Otitis media • Impetigo • Scarlet Fever • Rheumatic Fever • Pneumonia • GAS – Flesh eating ?

  4. Diphtheria • Corynebacterium diphtheriae • Metachromatic Granules • Pseudomembrane • Lysogenic conversion • Toxoid vaccine

  5. Whooping Cough • Bordetella pertussis • DTaP Vaccine • Diphtheria • Pertussis -acellular • Tetanus

  6. Tuberculosis • Mycobacterium tuberculosis • Primary • Tuberculin Test • Post primary • Tubercules • Isoniazid

  7. Other Mycobacterium spp • M. bovis • Hansen’s Disease • M. leprae • Leprosy

  8. Meningitis • Neisseria meningitidis • Meningococcus • 30% carriers • Other bacteria and viruses

  9. Viral Respiratory Pathogens • Common Cold • Rhinovirus • Influenza • Hemagglutinin • Neuraminidase

  10. Antigenic Shifts Polyvalent Vaccines

  11. Other Viruses • Red Measles • Rubeola • Mumps • German Measles • Rubella • MMR Vaccine

  12. Chickenpox Varicella Shingles Vaccine

  13. Staphylococcus aureus • Coagulase Positive • Boils • Impetigo • Toxic Shock Syndrome

  14. Gastric Ulcers • Helicobacter pylori • Discovered in 1983 • High carrier rate • Robin Warren & Barry Marshall • Nobel prize 2005

  15. Hepatitis • Liver Disease • Hepatitis A • People, food, water • Hepatitis B • Serum hepatitis • Hepatitis C • Cancer

  16. Sexually Transmitted Diseases • Gonorrhea • Neisseria gonorrhoeae • Syphilis • Treponema pallidum • Congenital Syphilis • Chancre • Secondary Syphilis • Tertiary Syphilis

  17. Other STDs • Chlamydia trachomatis • Lymphogranuloma venereum • Herpes simplex I • Cold sores • Herpes simplex II • Genital herpes

  18. AIDS Acquired Immunodeficiency Syndrome HIV Human Immunodeficiency Virus CD4 • Reverse • Transcriptase • Protease • Inhibitor

  19. Progression of HIV

  20. P to P Diseases Word List Boils Impetigo Toxic Shock Syndrome Diphtheria Corynebacterium diphtheriae Metachromatic Granules Airborne Transmission Respiratory Infections Streptococcus pyogenes S. pneumoniae Strept Throat β Hemolysis Otitis media Impetigo Scarlet Fever Rheumatic Fever Pneumonia Staphylococcus aureus Coagulase positive

  21. P to P Diseases Word List 2 Leprosy Viral Respiratory Pathogens Common Cold Rhinovirus Influenza Hemagglutinin Neuraminidase Pseudomembrane Whooping Cough Bordetella pertussis DPT Vaccine Tuberculosis Mycobacterium tuberculosis Primary Tuberculin Test Post primary Tubercles M. bovis Hansen’s Disease M. leprae

  22. P to P Diseases Word List 3 Neisseria gonorrheae Syphilis Treponema pallidum Congenital Syphilis Chancre Secondary Syphilis Tertiary Syphilis Rubella Chickenpox Varicella Shingles Sexually Transmitted Diseases Gonorrhea Antigenic Shift Polyvalent Vaccine Measles (Red) Rubeola Mumps MMR Vaccine German Measles

  23. P to P Diseases Word List 4 Acquired Immunodeficiency Syndrome Human Immunodeficiency Virus CD4 Reverse Transcriptase Protease Inhibitors Chlamydia trachomatis Lymphogranuloma venereum Herpes simplex I & II

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