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Exercise 1

Exercise 1. DNA identification. To which population an individual belongs?.

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Exercise 1

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  1. Exercise 1 DNA identification

  2. To which population an individual belongs? • Two populations of lab-mice have been accidentally put in a same cage. Your job is to sort the two populations to separate cages as precisely as possible. There were 50 individuals in population 1, and 10 individuals in population 2. • You pick randomly a mouse from the mixed population and apply a genetic test which reveals the genotype of the mouse in terms of two independent microsatellite loci • The allele frequencies in the two populations are known to be the following:

  3. Allele frequencies

  4. Classify the mouse… • Before knowing the result of the test, what is the probability that the mouse belongs to population 1? • What is the probability that the genotype in Locus 1 will be AA? • Analysis of the first locus shows that the genotype of the mouse is AA. What is the probability that the mouse belongs to population 1? • Next, you will analyze locus 2. What is the probability that you will find genotype bb? • The genotype in locus 2 seems to be bb. What is the probability that the mouse belongs to population 1?

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