650 likes | 795 Views
Biology Resources. Set 2: Answers for Structured Note-Taking. Living thing-organism 5 Characteristics: 1. Cells & DNA 2. Reproduce 3.Grow & Develop 4. Homeostasis 5. Adapt. 1. Cells & DNA Cell- basic unit of life DNA- genetic info 2. Reproduce *to further the species 3.
E N D
Biology Resources Set 2: Answers for Structured Note-Taking
Living thing-organism 5 Characteristics: 1. Cells & DNA 2. Reproduce 3.Grow & Develop 4. Homeostasis 5. Adapt 1. Cells & DNA Cell- basic unit of life DNA- genetic info 2. Reproduce *to further the species 3. 4. homeostasis *internal balance (kidneys sweating) Without it, you will die! 5. Adapt Adaptation: help you survive in environment Evolution: change in species over time Biology- The study of living thingsWho: Biologist- Interactions between living things- Interactions between living things and the environment- Problems to find solutions 5
SCIENTIFIC METHOD- a series of steps to solve a scientific problem 1. Problem 2. Hypothesis 3. Experiment 4. Data 5. Results 6. Conclusion 7. R/R or Repeat ----------------------------------- 1. Problem- scientific * Cannot be opinion * Give ex of opinion vs scientific 2. Hypothesis- a testable statement *give example 3. Experiment -a test of a hypothesis Independent variable: tested Dependent variable: measured Constant: same Control: normal to measure against 4. Data- info collected 5. Results- charts/graphs 6. Conclusion 7. Revise / Redo or Repeat -R/R- hypo wrong - Repeat- hypo right Why repeat: to verify results 7
WATER Properties: Polar- Great solvent --Like dissolves like-- --Polar dissolves polar-- Non-polar= oils, fats - will not dissolve Hydrogen Bonds: - gives H2O special properties - make/break rapidly 3 Things H2O does: 1. Capillary action Good- H2O to tops of trees 2. Stabilizes temp, holds heat (Good) NC ocean- mild climate Desert- hot day, freezing night 3. Expands when freezes – less dense Good- floats Water does these things because of Hydrogen bonds Water is Polar
ACID pH: 1-7 Gives- H+ burns Ex: lemon juice, stomach acid BASE pH: 7-14 Gives- OH- Soapy, cleaning Ex: cleaners, ammonia 7 Maintains constant pH Ex. Blood buffer Neutral H2O pH scale Buffer
Organic = has Carbon Living things have C [S]-[U]-[G]-[A]-[R] CARBOHYDRATES Polymer- polysaccharide Monomer- monosaccharide Uses quick Energy Ex. Starch, sugar, fiber Foods plant products/ fruit, veggies ORGANIC • Polymer • long chain of repeating units • Ex.train • [o]—[o]---[o]---[o] • Monomer • one unit • Ex. Train car • [o] 4 P R O T E I N (A)-(M)-(I)-(N)-(O)-(A)-(C)-(I)-(D) Polymer- polypeptide (protein) Monomer- amino acid Uses hair skin enzymes Food animal products, beans Ex. Enzymes (go to enzyme side) • Carbs • Protein • Nucleic Acid • Lipid Classes of organics
Nucleic Acid Enzymes • A type of protein • Subunit of protein amino acid • Job- “Biological Catalyst” • Affected by: temp & pH • Needed for: Biological Functions • Lock and Key Model • E are not consumed/used • In out Monomer- nucleotide Ex. – DNA/RNA Importance genetic info • LIPID • fats and oils • nonpolar • Meaning will not dissolve in H2O • Found in mayonnaise, butter • Greasy, oily
Before Microscopes: sick because cursed or punished for bad deed • Microscope Types: • Simple light – 1st type • 1 lens Energy Source light • LOW magnification power • 2. Compound Light • 2+ lenses Energy source light • Lens= 10 Objective = 4 • Total Magnification = 40 • Up to about 1500 X’s • Electron Microscopes • Uses beam of electrons • Magnify up to 500,000 X’s M I C R O S C O P E S • Microscope • tool used to look at small • organisms Micro – small Scope –to look at Microscopes allow US to see cells! Cell basic unit of life • SEM • scanning e-microscope • surface • TEM • transmission e-microscope • inside
Parts: Objectives, Diaphragm, Lens, Coarse Adjustment, Light Source, Arm, Stage, Fine Adjustment Match the part with the letter • Fine Adjustment E. Stage • Lens F. Diaphragm • Light Source G. Objectives • Coarse Adjustment H. Arm Answer Questions using Parts 1. __D__Used to bring objects into rapid focus first 2. __F__ Regulates the amount of light going through slide 3. __H__ Used to carry the microscope 4. __E__ Supports the slide 5. __A__ Turned to clear blurry pictures Answer Questions: How do you carry a microscope?- by the arm If the lens is 10 and the objective is 4, what is the total magnification?- 40
Famous Men Leeuwenhoek: saw microorganisms Used a simple microscope Robert Hooke: named a cell Used a compound microscope Looked at cork- Reminded him of rooms in a monastery Called cells T. Schwann: sounds like Swan All animals made of cells M. Schleiden: All plants made of cells Since all plants and animals are made of cells they concluded that… Hooke , Schleiden , Schwann Cells Plants Animals CELL THEORY 1. All living things are made of cells unicellular- 1 cell multicellular- 2+ cells 2. Cell is the basic unit of life The beginning unit is always a cell 3. All cells come from other cells CELLTHEORY cells organ organisms Organ system tissue muscle skin muscle skin skin muscle
Plasma Membrane Structure PLASMA MEMBRANE Polar head Tails non-polar (hydrophobic) • Plasma Membrane outer boundary of a cell - skin • Job- to maintain homeostasis • Homeostasis internal balance • PM is selectively permeable • selectively- choosy • Permeable – allows to pass • Selectively permeable chooses what it allows to pass phospholipids bilayer Polar: heads outside Non-polar: tails inside hiding from H2O Fluid mosaic model flexible Embedded w/ protein PM Perm mem Good in balanced nucleus Bad out
Cell organelles organs in a cell “organelle“ Most important = nucleus Nucleus controls all cell function Nucleus:Cell :: brain:body 2 Cell Types Prokaryote Eukaryote CELLS nucleus • no nucleus • no int membrane • simple • 1 job at a time • bacteria only • nucleus • int membrane • complex • multitask • plants/animals Animal cell Internal Membranes separate the cell into compartments Membranes : Cell :: walls: School Jobs – separate -divide -allow to multiply prokaryote eukaryote
Cell Theory • All living things made of • cells • 2. Cell is basic unit of life • All cells come from • pre-existing cells Plasma Membrane CELLS Plasma membraneis tocellas Skinis tobody RF: center covering Job: homeostasis Structure: phospholipids bilayer “ fluid mosaic model” Prokaryote Eukaryote Polar heads outside Nonpolar tails inside away from water • simple • no nucleus • no interior membrane • complex • nucleus • int membrane Other Cell Organelles Cell wall hard exterior covering Made of: cellulose Gives: extra protection Note plants only Nucleusis tocellas Brainis tobody Nucleus: controls all cell function Cell wallis tocellas Helmetis tohead Relating factor: Int memis tocellas Wallis toschool Internal Membrane: separate cell into rooms RF: hard protection RF: divide
Ribosome: • 2 types: • free • bound • Job make protein • *You can’t live without PROTEIN* Vacuole: Description- empty sac job- store food, H2O NOTE plant cell larger Vacuoleis tocellas Fridge is tohouse ribosomeis tocell as Protein factory is tocity RF: stores • Mitochondria: • makes energy • ATP • *You can’t live without ENERGY!!* RF: makes protein Mitochondriais tocellas Battery is toobject Chloroplast: Description- green job- make food/ photosynthesis Chlorophyll- traps sunlight NOTE plants only RF: energy Chloroplastis tocellas Kitchen is tohouse ATP • Eukaryotes: • Have membrane bound organelles • Have nucleus • Prokaryotes: • Have plasma membrane • Have DNA • Have Ribs • b/c must have protein RF: room to make food
Concentration: Amount of solute in solution. Think kool-aid Highlow Lots of solute not enough solute Solute (green) will move from high to low Goal: Concentration Dynamic Gradient Equilibrium DIFFUSION • difference in conc on sides • 7/3 • equal • 5/5 A B A B A B To side A A Solute (green) will move to B (think elevators and buffet lines. Where would you rather be?) B A B To side B
Remember Diffusion movement of a solute to low (less crowded) Driven by: concentration gradient Result: DE Which side needs to be diluted? A So water will go to side A OSMOSIS • Review concentration: (think kool-aid) • HighLow • Too much not enough • Dilute add water to lower conc. • OSMOSIS • movement of water to high • Why: to dilute • Driven by: CG • Result: DE More water on side A because more particles Water will move to side B Why? To dilute high
Water will move to side A Why? To dilute CELLOSMOSIS Plant • Where is there more? in • So water flows? in • Results: swells • Puts pressure on inside wall More : out Water flows: out Result: shrivels Sides: equal So: no flow Result: no pressure 9 3 Animal Water Flows 2 6 3 3 8 2 4 Cell
Passive • no energy • Happens because there is a • Concentration gradient • Result- dynamic equilibrium • 1. Diffusion • 2. Osmosis • 3. Facilitated Diffusion • Active • uses energy • Requires energy to: move against conc grad • Result: more unequal • 1. pumps • 2. carriers • 3. endocytosis, exocytosis TRANSPORT A B Passive: to side B Active: pumped to side A
Cell cycle cycle for cells to make new cells • “All cells come from pre-existing cells” Cells must reproduce DNA in cells chromatin • unpacked • chromosome • packed DNA • visible when stained Cell cycle: 1. Interphase: grow & DNA duplicate 2. Mitosis: nucleus divides 3. Cytokinesis: cut cell in half MITOSIS centromere Sister chromatids
# 1 Source of energy- sun Cell energy- ATP “Adenosine Triphosphate” A – P – P – P Release Energy break bond Store Energy make bond Remove –P leaves A–P-P (ADP) Remove –P leaves A – P (AMP) Which has more energy? ATP Why? More P-P bonds *Made in the mitochondria • Photosynthesis • Who plants • Where chloroplast • Job- to make food + O2 • Plants take In Out • CO2 -O2 • water H2O -food • sun E • Reactant in Product out • Eq: 6CO2+6H2O+E6O2+C6H12O6 ENERGY Sun chemical food E E E C6H12O6
Cellular Respiration Where mitochondria Job to make ATP • In • O2 • C6H12O6 • Out • CO2 • H2O • E-ATP Also called fermentation Reactant IN Product OUT Eq: 6O2+C6H12O6 6CO2+6H2O+E Notice: Products of PS are reactants in CR Lactic Acid Fermentation CO2 Alcoholic Fermentation O2 food Cellular respiration photosynthesis
Chemistry and Cell Review “polar“ Acid Base pH 1-7 H+, burns pH 7-14 OH-, cleans • Parts of cell theory • all living things made of cells • the cell is the basic unit of life • all cells made from pre-existing cells
Cells basic unit of life Cell tissue organ organ system organism Cell Parts Nucleus– control Plasma Membrane- outer covering Mitochondria- energy Chloroplast- food- photosynthesis Ribosome- protein Vacuole- store food
A B Water will flow to A Why- needs to dilute Result- dyn eq Process- osmosis Solute will move to B Why- less concentrated Result- dyn eq Process- diffusion 7 3 5 2 Water goes: in - swell 8 Water goes: out - shrivel 5 Water goes: no flow - stable
Tele Meta Mom Ana Prop A B C D E F Place the phases in order: D A F C E B and name them mitochondria Cell Energy ATP Adenosine triphosphate - Energy stored in P-P bonds Cellular Respiration We breathe in O2 We eat C6H12O6 We breathe out CO2 Make H2O + ATP Anaerobic No oxygen, less ATP fermentation Photosynthesis IN OUT H2O, CO2, E O2, C6H12O6 Eq: 6CO2+6H2O+E6O2+C6H12O6 Chloroplast Aerobic Oxygen, more ATP
DNA – deoxyribonucleic acid • Codes for genetic info • Gives info to make protein • Importance of protein: • can’t live without protein • codes for traits (eye color, hair) • DNA is very important information Where nucleus • Question- An enzyme helicase cuts segments of DNA to repair damaged cells. Where in the cell is this enzyme located? nucleus Structure Polymer = DNA -long chain of joining subunits Subunit nucleotide Nucleotide (3 parts) 1. Sugar deoxyribose 2. phosphate 3. Nitrogen bases (4) Nitrogen bases (4) 1. Adenine A 3. Cytosine C 2. Guanine G 4. Thyamine T Purines pyrimidines D N A G E N E T I C C O D E Note DNA cannot leave nucleus Ad Gua Cy Thy
Important structure note: • DNA is a double helix • Watson & Crickmen • 2 strands • Like a ladder Bases always held together by hydrogen bonds So DNA looks like this Backbone S-P-S-P backbone Repeating S-P-S-P-S-P Bases held together by hydrogen bonds Nitrogen bases A-- G-T- C- A-- T-- ?-- --T --C --A --G --T --A Complementary bases they always go together A= T C= G Hydrogen bonds Make the DNA complement
R E P L I C A T I O N • Review • Make the complement: • ATCTAAGCAGGTA • TAGATTCGTCCAT • TACGGATACCGAAT • ATGCCTATGGCTTA • How: • Enzyme splits it • Complement strands made • Result Replication makes a copy Replication DNA synthesis make DNA DNA codes for protein Proteins made on ribs Problem DNA cannot leave nucleus Info must get to the nucleus Solution RNA Word Attack: Synthesis to make Replication makes a copy Why for new cells When interphase Where nucleus
Review: • RNA – ribonucleic acid • 1 Strand • Nucleotide (3) • Sugar ribose • phosphate • Nitrogen base • * A *G *C * U (uracil) • A U • C G • Made by transcription Transcription DNA- ATCGTATCA RNA- UAGCAUAGU DNA- TACCGATCCCATC RNA- AUGGCUAGGGUAG DNA- GACCCGTCATCCGGTAATAATCCAT RNA- CUGGGCAGUAGGCCAUUAUUAGGUAU DNA RNA . R N A • deoxyribonucleic acid • 2 strands • deoxyribose sugar • Bases A=T G=C • made by replication • cannot leave nucleus • ribonucleic acid • 1 strand • ribose sugar • bases A=U C=G • made by transcription • nucleus- ribosome Transcription Makes RNA from DNA Where: nucleus
Review: DNA RNA . Bases- AT, CG Bases-AU, CG Process- replication Process- transcription P R O T E I N • How to find out what amino acids to use: • Use chart • Use codons • Codon set of 3 nb used to code for AA • Let’s Practice! • CAU – His • UUU –Phe • UUA – Leu • GAA – Glu • CCC – Pro • CGC – Arg • Does chart use RNA or DNA? RNA • So If you have CAT? GUA Job to make protein Protein a long chain of amino acids Process translation Translation to make protein by joining amino acids
Remember DNA RNA . T R A N S L A T I O N • deoxyribose • 2 strands • AT CG • replication • cannot leave nucleus • ribose • 1 strand • AU CG • transcription • nucleus- ribosomes • Protein monomer amino acid • Codon: set of 3 nb • Translation make protein • Ex: ACU I GUU I CAU • Divide into 3’s • 2. Find amino acid on chart • Protein Thr – Val – His • Ex: • TAC GAA CCC GTA CAA ACT –DNA • AUG CUU GGG CAU GUU UGA -RNA • protein A = T(DNA) A = U(RNA) C= G 3 parts of a nucleotide: 1. sugar 2. phosphate 3. Nitrogen base Replicate: ATCCATGAACTATAG TAGGTACTTGATATC Transcribe: ATCCATGAACTATAG UAGGUACUUGAUAUC 3 types RNA: 1. mRNA: messenger 2. tRNA: transfer 3. rRNA: ribosomal
M U T A T I O N • THE DOG BIT THE CAT • THE DOG BIT THE CAR • TED OGB ITT HEC AT_ • 1 Point-Substitute: changes 1 amino acid • 2 Frameshift: delete/insert. Changes all amino acids • Review: • Make the DNA complement: • CATGACTTAATGCGA • GTACTGAATTACGCT • 2. Transcribe: • CATGACTTAATGCGA • GUACUGAAUUACGCU • Translate: • CAT GAC TTA ATG CGA • GUA CUG AAU UAC GCU • RNA • mRNA- MESSENGER • tRNA – TRANSFER • rRNA – RIBOSOMAL
DNA Mini Lab • Normal hemoglobin vs. Sickled hemoglobin • Normal hemoglobin carries oxygen • Sickled hemoglobin cannot carry oxygen • Why They make different proteins • Job: Transcribe and translate the DNA of the 2 types of hemoglobin • Normal: GGG CTT CTT TTT • Sickled: GGG CAT CTT TTT • Using AAT GCC AGT GGT TCC CAC • what protein would it make? • Contrast replication, transcription and translation: • Contrast RNA and DNA: • What are the 3 parts of a nucleotide?
GENETICS Father of Genetics: Gregor Mendel Gene: segment of DNA that codes for a protein/trait Allele: choices for a trait/gene Ex: gene- eye color gene- height Alleles- brown, blue alleles- tall short Heredity: passing of traits from parents to kids Genetics: study of heredity Traits: characteristics you get from parents Gametes: sex cells MomDad Egg sperm Fertilization- union of sperm and egg Zygote – fertilized egg Dominant Recessive Always seen T Can be hidden and skip generations t Law of Segregation: Get 1 allele for each trait from each parent So you end up with – 2 alleles for each
How do you predict what offspring will look like? • Punnet Square • Tool used to predict genotype and phenotype of offspring • B=black b=tan • Mom - Bb Dad- Bb • Looks black Looks black • Cross parents • Bb x Bb • mom dad • Draw box • Put mom gametes on top. Put Dad gametes on side. • Fill in box with a letter from each parent • Analyze Since you have 2 alleles for each gene, you have 2 letters (Remember baby lab) TT homozygous dominant (Tall) Tt homozygous recessive (short) Tt heterozygous (tall) Big letter ALWAYS wins Genotype Phenotype Combo of alleles Tt Bb Physical trait Tall, short B b B b
Pair up letters in the following combinations • BbTt • 1234 • 1,3 1,4 2,3 2,4 • BT Bt bT bt • Dihybrid Crosses • 2 different traits/parent • B = brown b = white • T = tall t = short • BbTt – brown tall • Bbtt - brown short • bbTT - white tall • BBtt - white short • Rules for dihybrids • Ex: BbTb x Bb TT • Label mom and dad • Mom- BbTt dad BbTT • 2. Take mom and label letters 1-4 • BbTt • 1234 Notice: never 2 of the same letter in a pair • Repeat for Dad • BbTT • 1,3 1,4 2,3 2,4 • BT BT bT bT • 5. Draw Punnet square • How many squares will you have? • BbTt x BbTT • 4 X 4 = 16
Square: 4 across, 4 down Q1: T – tall t – short R – round r – white TtRR x TtRr • Place Mom’s 4 combos on top • Place Dad’s 4 conbos down side • Fill in boxes • Each box will have 4 letters • Using our example how many offspring will be: • BBTT: 2 BBTt: 4 • bbTt: 2 BbTt: 4 • BbTT: 4 • Brown tall: 12 white tall: 4 How many are tall round? 12 What are the genotypes? TTRR TtRR TTRr TtRr ttRR ttRr Remember combos: 1,3 1,4 2,3 2,4
G E N E T I C T E C H N O L O G Y • Uses: • Forensics • DNA obtained from: • If know DNA sequences: • Other uses of Genetic Technology: • Industry • Medicine • Agriculture
Pedigree: a genetic family P E D I G R E E female male How is person 7 kin to person 1? Son InLaw How are 6 and 9 kin? Aunt/nephew How is 1 kin to 13? Great grandson How many males? 6 Females? 7 How many affected people? 5 Males? 3 Females? 2 If trait studied is tt – short: Give the gen/phen for each person 1 Tt tall 8 tt short 2 Tt tall 9 Tt tall 3 Tt tall 10 Tt tall 4 Tt tall 11 tt short 5 tt short 12 Tt tall 6 Tt tall 13 tt short 7 tt short Persons _5,7,8,11,13_ are short affected affected married children carrier Carrier: Tt – carries the t but is not affected by it
Recessive Diseases: • Cystic Fibrosis: • Buildup of mucous in lungs • Pedigree: • Note: only child affected • For a recessive disease to affect a child both parents must be: carriers Practice Pedigrees: Which people are affected? 3, 6 Label each person bb- blue BB or Bb - brown This is a recessive pedigree Because 2 unshaded parents have an affected child Most genetic disorders are caused by: 2 recessive alleles Carrier: carries the allele but are not sick Cc What % Chance will 2 carrier parents have a sick child? 25%
H U M A N T R A I T S • Most genetic disorders are caused by 2 recessive alleles • Cystic Fibrosis: • A buildup of mucous in lungs • Affects mostly children • Tay-Sachs • -affects the brain • -Cannot break down lipid/fat • -Mostly affects children • PKU • -found in protein • -cannot digest protein • - Controlled by diet • Dominant Traits: • Hitchhiker thumb • Unattached ear lobes • Thick lips • Huntington’s Disease: • Causes brain degeneration • Affects people 35 to 45 • Why do people with Huntington’s have children not know they are sick • If you carry the gene for Huntington’s you are affected by it • H = has it h = does not
If a child with free hanging earlobes has a mother with attached earlobes, could a man with attached earlobes be the father? No • Why? No big F’s to give • F = free f = attached • 6. • 1. Which is Huntington’s? A • Which is cystic fibrosis? B • How do you know? • How is Huntington’s different? Older age, dominant • Define the following: • What body part is affected by CF? lungs male female # affected: 6 How are 9 and 6 kin? aunt Gen/phen of person: 2 ff att 7 Ff 3 Ff 9 Ff 4 ff att 11 Ff 13 ff att married carrier
Blood Type- codominance and multiple alleles Multiple alleles more than 2 choices TypeGenotype A IA IA IA Ii B IBIB IBi AB IAIB O ii Who did the blood bank Charles Drew blood transfers If a son has blood type O could a msn with blood type B be Dad if the Mom has A? What % chance do an A (Ia,i) woman and a B (Ibi) man have of having an O child?
Humans have 46 Into 23 pairs Karyotype chart of paired chromosomes C H R O M O S O M E S Chromosomal Diseases: Down’s Syndrome 3 on 21st pair -mental and physical retardation D-S male 23 23rd pair - sex chromosomes XX - female XY - male The chart shows a normal female Monosomy 23 female copy
Sex-linked diseases Female – XX Male - XY Travel on the X Red/Green colorblindness Hemophilia: bleeder. Cannot clot blood Pedigree: Notice: mom is carrier. Passes it to sons More males affected Why? FemaleMale XxX XxY Can a carrier female and an affected male have an affected daughter? Can a normal female and an affected male have an affected daughter? 0 Son? 0 Where does a son get his bad X? mom Who does dad give his bad X to? daughter Good X takes over Only 1 X and it’s affected
O R I G I N O F L I F E • Primitive Earth • Deadly Gases • Oparin Hypothesis • 3.9 billion years ago • This caused • 2 things happened: • 1. • 2. • Lightning and carbon in ocean formed: • These combined to form _________ • Protocell (organic) _________ (simple) ___________ (complex) Primitive Earth: NO LIFE How did life begin?
Evidence for Evolution • Fossils- oldest _________ • fossil record • Biochemistry – • Embryology – • Anatomical Structures • similar vestigial • Urey and Miller • Can Oparin be for real? Urey and Miller tested him. How? • Result they found … • Urey and Miller support Oparin • Hypothesis • Where: in the __________
ECOLOGY Ecology: the study of organisms and their environment Who? ecologist Biotic factors abiotic factors 1. Organism - 1 living thing Ex. 1 giraffe 2. group - 2+ of same species Ex.giraffes 3. community - 2+ different species Ex. Zebras and giraffes 4. ecosystem - Living and nonliving Ex. Zebra, giraffe, tree, and sun 5. biosphere - Can support life Ex. Sphere = circle Bio = life EARTH! Living Plants, animals, predators Nonliving Sun, dirt, temp 5 levels of ecology: 5 • organism • population • community • ecosystem • biosphere
Interactions: • Competition- fighting over resources • Habitat Niche . • Where it lives • Ex. In a tree • Reduces competition: by having organisms w/ diff niches/needs • Predator/Prey • Predator: eats • Prey: gets eaten • Cyclic • Prey up, predator up, then prey gets eaten, levels down, predator down from lack of food, then back to beginning as prey makes comeback • Density dependent depends on size of population • Symbiosis living together, nothing dies • Mutualism: 2 (both) benefit • • Ex. Fish in coral • Commensalism : 1 benefit, 1 unaffected • :l • Parasitism: 1 benefit, 1 harmed • • Ex. Leeches on a host What it does- job Ex. Collect acorns