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SIRIUS Trial: Diameter Restenosis

SIRIUS Trial: Diameter Restenosis. P<0.001. P=0.001. % Proximal Segment. % In Segment. % Distal Segment. % In stent. P=NS. P=0.14. Coated. Bare. Coated. Bare. Coated. Bare. Coated. Bare. Peristent Restenosis (PSR): 5 mm proximal and distal to the stent

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SIRIUS Trial: Diameter Restenosis

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  1. SIRIUS Trial: Diameter Restenosis P<0.001 P=0.001 % Proximal Segment % In Segment % Distal Segment % In stent P=NS P=0.14 Coated Bare Coated Bare Coated Bare Coated Bare Peristent Restenosis (PSR): 5 mm proximal and distal to the stent In stent Restenosis (ISR): within the margins of the stent In Segment: Sum of PSR and ISR Euro PCR 2002

  2. SIRIUS Trial: Late Loss (mm) P=0.001 P=0.009 P=0.14 P<0.001 In Segment Distal Segment Proximal Segment In stent Coated Bare Coated Bare Coated Bare Coated Bare Peristent Restenosis (PSR): 5 mm proximal and distal to the stent In stent Restenosis (ISR): within the margins of the stent In Segment: Sum of PSR and ISR Euro PCR 2002

  3. SIRIUS Trial: Minimum Lumen Diameter at Follow-Up (mm) P<0.001 P<0.001 P<0.001 In stent MLD (mm) In stent MLD (mm) In stent MLD (mm) Coated Bare Coated Bare Coated Bare Small Vessels: Median 2.30 Medium Vessels: Median 2.79 Large Vessels: Median 3.00 Euro PCR 2002

  4. SIRIUS Trial: In Stent Restenosis at Follow-Up (%) P<0.001 P<0.001 P=0.002 In stent Restenosis (%) In stent Restenosis (%) In stent Restenosis (%) Coated Bare Coated Bare Coated Bare Small Vessels: Median 2.30 Medium Vessels: Median 2.79 Large Vessels: Median 3.00 Euro PCR 2002

  5. SIRIUS Trial: In Segment Restenosis at Follow-Up (%) P=0.002 P<0.027 P<0.001 In segment Restenosis (%) In segment Restenosis (%) In segment Restenosis (%) Coated Bare Coated Bare Coated Bare Small Vessels: Median 2.30 Medium Vessels: Median 2.79 Large Vessels: Median 3.00 Euro PCR 2002

  6. SIRIUS Trial: Lesion Length and IVUS Findings Plaque Volume NIH IVUS Volume Restenotic Lesion Length (mm) Coated Bare Coated Bare Coated Bare Euro PCR 2002

  7. SIRIUS: Loss Index (Late Loss / Acute Gain) In Segment In Stent Loss Index Euro PCR 2002

  8. SIRIUS: TLR and TVF Target Lesion Revasc (TLR) Target Vessel Failure (TVF) P<0.001 P<0.001 Incidence (%) Euro PCR 2002

  9. SIRIUS: Clinical Events Incidence (%) Coated Bare Coated Bare Coated Bare Coated Bare Coated Bare Coated Bare Stent Thrombosis < 24 hrs Non Q wave MI Stent Thrombosis Day 1 - 30 Q wave MI Death MACE Euro PCR 2002

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