1 / 12

Characterization of Higher Order Ocular Aberrations (HOA) In ‘Normal’ Versus Myopic Eyes To Study The Effect Of Myopia O

Characterization of Higher Order Ocular Aberrations (HOA) In ‘Normal’ Versus Myopic Eyes To Study The Effect Of Myopia On Higher Order Aberrations. Amit Gupta MS Manish Chaudhary MS Advanced Eye Centre, Postgraduate Institute of Medical Education & Research, Chandigarh India

zuwena
Download Presentation

Characterization of Higher Order Ocular Aberrations (HOA) In ‘Normal’ Versus Myopic Eyes To Study The Effect Of Myopia O

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Characterization of Higher Order Ocular Aberrations (HOA) In ‘Normal’ Versus Myopic Eyes To Study The Effect Of Myopia On Higher Order Aberrations • Amit Gupta MS • Manish Chaudhary MS • Advanced Eye Centre, • Postgraduate Institute of Medical Education & Research, • Chandigarh • India • (Email : amitguptaeye@gmail.com) The authors have no financial interest in the subject matter of this poster

  2. Role of Wavefront error assessment: • Quantitative assessment of the optical properties of the eye • To evaluate therapy (eg: refractive surgery) designed to improve the optical properties of the eye • Provides the necessary information to design optical prescriptions for the eye to minimize all refractive errors. Ethnicity and refractive errors significantly affect the wavefront aberrations. Carkeet A et al Luo H, Tong L, Saw S, Tan D. Refractive error and monochromatic aberrations in Singaporean children. Vision Reseach 2002;42:1809-1824. This study aimed to establish normative data on HOA in Indian population as well as to study the effect of refractive error on HOA.

  3. Purpose Patients and Methods To Characterize Higher Order Ocular Aberrations (HOA) In ‘Normal’ Versus Myopic Eyes In Order To Study The Effect Of Myopia On HOA in the Indian Population Study Design: An observational cross sectional prospective study Study Population • Group I : 500 emmetropic eyes (refractive error 0+0.25 D) • Group II : 500 myopic eyes (refractive error > -0.25 to < -6.0 diopters)

  4. Methods Inclusion criteria • Age 18-40 years. • Best corrected visual acuity (BCVA)of 6/9 or better. • Normal ocular examination, emmetropia or Myopia < 6 D. Patient Workup: • Best Corrected Visual Acuity, • Slit Lamp Biomicroscopy, • Refraction, • Schirmer’s test, • Aberrometry: :Optical Path Difference (OPD) Scanning done after dilating with 0.8% tropicamide and 5% phenylephrine using ARK-10000 OPD scan (NIDEK Technologies, Japan) Exclusion criteria • Corneal degenerations and dystrophies • Corneal scarring after infective diseases • Dry eye patients • Any Other ocular pathology

  5. Aberrometric Data Interpretation and Analysis Step 1: OPD Scan Analysis Step 2: Zernike polynomials were transformed into • Root mean square (RMS) of higher order aberration (HOA) from the 3rd to 6th orders • RMS of the spherical aberration (SA) (square root of the sum of the squared coefficients of Z4 0 and Z60), • RMS of coma (square root of the sum of the squared coefficients of Z3-1, Z31, Z5-1,and Z51), • RMS of trefoil (square root of the sum of the squared coefficients of Z3-3, Z33, Z5-3,and Z53 Thibos et al. Standards for reporting the optical aberrations of eyes. J Refract Surg 2002; 18:S652–S660 Step 3: Statistical Analysis • ‘t-test’ (for normal Distribution) & for skewed data Mann- Whitney test. • Relationship between different variables using Spearman and Pearson correlation coefficient Aberrometric Analysis by OPD Scan

  6. Results Patients characteristics in emmetropic and myopic group Both the groups were age matched

  7. Ocular Aberrations in Emmetropic versus Myopic Eyes All the ocular aberration were significantly higher in myopic group

  8. Comparative data of wavefront aberrations ( Emmetropic versus myopic eyes ) All the ocular aberration were statistically higher in myopic group

  9. Correlation of HOAs with Degree of Myopia Correlation of ocular aberrations with magnitude of Myopia Contribution of each order to the overall Higher Order aberrations in emmetropic and myopic eyes Amount of HOAs are well correlate to amount of refractive error as the amount of refractive error increase the amount of HOAs increases

  10. Scatter diagram Showing the Correlation of HOAs with degree of Myopia HOAs are correlated with amount of refractive error as the amount of myopia increase the value of HOAs increases

  11. Comparison of our aberrometric data with reported data

  12. Summary And Conclusions This is the first study comparing wavefront aberrations in the emmetropic versus myopic eyes in Indian population. The emmetropic and myopic groups showed significant differences for higher order aberration for 3rd, 4th, 5th and 6th-order aberrations. All the differences were highly significant (p<0.001) Ocular wavefront aberrations varied greatly from subject to subject. There was no correlation with age as well sex of individuals in both groups. Amount of refractive error significantly affects the amount of aberration. As refractory error increases, the amount of aberration as well as HOAs also increases but this correlation is not a linear relation The right and left eye of subjects showed no significant difference in amount of HOAs and well correlated to each other.

More Related