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Evidence for microevolution by natural selection Drug-resistance Mutation 1 st , drug selects for it. Evidence for microevolution by natural selection industrial melanism in peppered moths < 1850 were light > 1850 went dark soot coated trees Kettlewell: dark moths survived on dark
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Evidence for microevolution by natural selection • Drug-resistance • Mutation 1st, • drug selects • for it
Evidence for microevolution by natural selection • industrial melanism in peppered moths • < 1850 were light • > 1850 went dark • soot coated trees • Kettlewell: dark • moths survived on dark • trees, light on light
Evidence for microevolution by natural selection Dark moths survived on dark trees, light on light Now select light moths
Evidence for microevolution by natural selection • HbS: human microevolution • malaria selects • Het have more kids
Evidence for microevolution by natural selection • HbS: human microevolution • Freq. HbS allele correlates with malaria
Other evidence for microevolution in humans? • Skin color • Dark in tropics to block UV • Light in N for vit D
Other evidence for microevolution in humans? • AIDS resistance • Humans homozygous for CCR5 ∆32 are “immune” to HIV • Humans heterozygous • for CCR5 ∆32 are • resistant • Humans are evolving!
Humans are evolving! Mutation? Gene flow Genetic drift Outcrossing
Selection has changed • less "old disease" • less birth defects • less famine • New selection • diseases • drugs • cars • pollution • birth control • Humans in 10,000 AD will have evolved!