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Dr. Hasmaliza Mohamad Radin Shafinaz Jamil Materials Engineering

School of Material & Mineral Resources Engineering. Dr. Hasmaliza Mohamad Radin Shafinaz Jamil Materials Engineering. The Synthesis of Porous Alumina Trough Sol-gel Combustion for Biomedical Application. Enhance the osteoblast adhesion. Background:

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Dr. Hasmaliza Mohamad Radin Shafinaz Jamil Materials Engineering

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  1. School of Material & Mineral Resources Engineering Dr. Hasmaliza Mohamad Radin Shafinaz Jamil Materials Engineering

  2. The Synthesis of Porous Alumina Trough Sol-gel Combustion for Biomedical Application Enhance the osteoblast adhesion

  3. Background: • Major causes of implant loosening: incomplete osseointergration (Khang, 2008). • To overcome: modifying the implant/bone interface (Baxter, 2000). • Nanoporous alumina with the pore sizes range between 30 – 80 nm has been develop by two-step anodization (Karlsson, 2003). • The nanoporous alumina did improve the osteoblast adhesion. • Present study: • Nanoporous alumina with 30 – 80 nm will be produce trough sol – gel combustion. • Objective: • To use porous alumina produced trough sol-gel combustion to enhance the interface of bone cell and implant device (bone cell adhesion)

  4. Alumina Properties • High strength and modulus. • High wear resistance • Chemical inertness

  5. ingrowths tissue trough the pores Increase interfacial area Establishment of interface Increase movement resistance Function of nanoporous alumina • With nanoporous structure the adsorption of the proteins and minerals will give a better result for the adhesion.

  6. Figure: Alumina will be place between bone – implant device

  7. Combustion • Advantages: • time and energy savings. • Can produce homogeneous, high-purity and high crystalline oxide ceramic powders • Capable to produce a pure phase with ultrafine powder at a low calcinations temperature • Environmentally clean processing • Easy technique to produce porous structure.

  8. Porous alumina produce via combustion with magnification of 10K X

  9. Raw materials Solution of mixture combustion Foamy product calcine α - alumina Flow Process:

  10. Type of fuel Fuel–to–oxidizer ratio Ignition temperature Pore size Pore distribution Pore shape Parameters & Properties variation Parameters Properties Effect

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