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Automated Insulin Preparation System

Automated Insulin Preparation System. Progress Report Group 22: Brant Cauthorn, Jessica Filderman, and Kellie Stoka Client: Dr. Klaesner. Product Need. Prevalence 366 million people worldwide 1 Cost $465 billion a year worldwide 1 50% of people inject insulin wrong 2

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Automated Insulin Preparation System

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  1. Automated Insulin Preparation System Progress Report Group 22: Brant Cauthorn, Jessica Filderman, and Kellie Stoka Client: Dr. Klaesner

  2. Product Need • Prevalence • 366 million people worldwide1 • Cost • $465 billion a year worldwide1 • 50% of people inject insulin wrong2 • Why people do it wrong: • Visual Impairment • Peripheral Neuropathy • Arthritis • Chang, Maria. The Huffington Post, 13 September 2011. • Wartburg, Linda. Diabetes Health, 21 March 2009.

  3. Design Requirements • General: • Small size • Inexpensive • Can be used in a home setting • Limited complexity • Operation: • Safe • Accurate • Not limited by user health conditions • Room Temperature • Minimum functions: • Hold two 10 ml insulin vial(s) • Mix insulin vial(s) • Sterilize vial(s) • Uncap needles • Insert needle into vial(s) • Withdraw a specified amount of insulin

  4. Design Process • Optional Features • Injection Capability? • Temperature Control? • Blood Glucose Monitor? • Storage of Vials? • Data Communication? • Dose Verification? • Required Features • User Interface • Dose Vessel • Mixing • Sterilization • Setting Dose • Power Source

  5. Design Alternatives – Optional Features • Injection Capability? • No • Temperature Control? • No • Blood Glucose Monitor? • No • Storage of Vials? • Yes • Data Communication? • Yes • Dose Verification? • Yes

  6. Design Alternatives – User Interface Manual “Keys” Keypad Voice Recognition External Computer Barcode Scanner

  7. Design Alternatives – User Interface

  8. Design Alternatives - Mixing • Conveyor Belts • Drop Down Slot • Vortex • Vertical Arm Shaker • User Mixing • Tilt Shaker • Horizontal Platform Shaker

  9. Design Alternatives - Mixing

  10. Design Alternatives - Sterilization • Spray top of vial with isopropyl alcohol • Wipe top of vial with isopropyl alcohol pad • Dip top of vial in isopropyl alcohol • Heat top of vial • User sterilizes vial

  11. Design Alternatives - Sterilization

  12. Design Alternatives - Container • What will hold the insulin? • Syringe • Insulin Pen Cartridge • Catheter

  13. Design Alternatives - Container

  14. Design Alternatives - Syringe • Traditional Syringe • Significant user difficulty • Modified Syringe • Moderate user difficulty • New Syringe Design • Minimal user difficulty ???

  15. Design Alternatives - Syringe • New Syringe Design

  16. Design Alternatives - Syringe

  17. Design Alternatives – Setting Dose and Drawing Up Insulin • Stepper Motor • Spacers • Bar • Pressure

  18. Design Alternatives – Setting Dose and Drawing Up Insulin

  19. Design Alternatives – Dose Verification • Weight • Weigh vials before and after drawing insulin • Use density to determine volume change • Light • Shine light through syringe, measure absorption • Raise light vertically until absorption changes (Insulin-air interface)

  20. Design Alternatives – Dose Verification

  21. Chosen Design

  22. Next Steps • Select materials and parts • Determine precise assembly of parts • What happens if machine malfunctions • Choose convenient locations for supply input • Machine waste removal

  23. Schedule

  24. Team Responsibilities • Brant – Website Design and Maintenance, CAD Drawings • Kellie – Material & Manufacturing Requirements, CAD Drawings • Jessica – Risk Analysis, Report Editing

  25. Questions?

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