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Retroviruses and Novel Drugs Chicago, USA June 08-09, 2015 David Sando MDH

Temporal Trends in Clinical Characteristics and Outcome of Patient ’ s enrolled in ART program, 2004-2011 in Dar es Salaam, Tanzania. Retroviruses and Novel Drugs Chicago, USA June 08-09, 2015 David Sando MDH. Outline. Overview of country HIV/AIDS epidemic

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Retroviruses and Novel Drugs Chicago, USA June 08-09, 2015 David Sando MDH

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  1. Temporal Trends in Clinical Characteristics and Outcome of Patient’s enrolled in ART program, 2004-2011 in Dar es Salaam, Tanzania. Retroviruses and Novel Drugs Chicago, USA June 08-09, 2015 David Sando MDH Retrovirus conf, Chicago, June 09, 2015

  2. Outline • Overview of country HIV/AIDS epidemic • Key national programs to fight the epidemic • MDH overview • Methods • Results • Summary • Acknowledgements Retrovirus conf, Chicago, June 09, 2015

  3. Retrovirus conf, Chicago, June 09, 2015

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  5. Retrovirus conf, Chicago, June 09, 2015

  6. HIV Counseling and Testing Retrovirus conf, Chicago, June 09, 2015

  7. Condom use and HIV Retrovirus conf, Chicago, June 09, 2015

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  9. MDH HIV clinic in DSM

  10. Key supported program areas • HIV care and treatment • PMTCT and HIV early infant diagnosis • Infrastructure improvement • Capacity building/trainings/ mentorships • ARVs and health commodities management • Strengthening laboratory services • Quality Improvement initiatives • Data Mng for M&E and Strategic Information • Community linkage and tracking • Nutritional support • Promotion of HIV prevention and PWP • Public Health Evaluations and Evidence-Based Programming

  11. Scaling up of Care and treatment services

  12. Methods • Study period: October 2004 – September 2011 • Socio-demographics, clinical and immunological data at enrollment were collected • Their outcome data, such as still active on ART, LTF and dead were also collected on routine basis. • Year of enrollment was treated as independent variable • Binomial logistic regression model was used for trend tests. • P-values under 0.05 were considered significant. Retrovirus conf, Chicago, June 09, 2015

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  19. Summary • Overall, there has been increase in enrollment of HIV patients over time • Despite an early observed worsening of clinical features, recent years new patients presents in less advanced stage of disease • LTF has been persistent high over the years since start of the program • There has been decrease in overall 12-month mortality rate Retrovirus conf, Chicago, June 09, 2015

  20. Acknowledgements • The gov’t of Tanzania through Ministry of Health and Social welfare • The Dar es Salaam regional secretariat and its municipal councils health management teams • Management and Development for Health staff • This study has been supported by the US President’s Emergency Plan for AIDS Relief (PEPFAR) through Centers for Disease Control and Prevention under the terms of SHAPE Project Award # GH11‐112703CONT13

  21. THANK YOU FOR LISTENING Retrovirus conf, Chicago, June 09, 2015

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