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December Luncheon Meeting Steve Mandell, Chairman Pepper Hamilton LLP Annual Holiday Luncheon Science Quiz

2. Science in the NewsQuiz Questions. 3. What material obtained from recycling has been found to be superior to, and cheaper than, other materials for waste water filtration? Old tires, chopped and ground to crumbs - Washington Post, Science Notebook.. 4. A Philadelphia company is using the remna

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December Luncheon Meeting Steve Mandell, Chairman Pepper Hamilton LLP Annual Holiday Luncheon Science Quiz

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    1. 1 December Luncheon Meeting Steve Mandell, Chairman Pepper Hamilton LLP Annual Holiday Luncheon & Science Quiz

    2. 2 Science in the News Quiz Questions

    3. 3 What material obtained from recycling has been found to be superior to, and cheaper than, other materials for waste water filtration? Old tires, chopped and ground to crumbs - Washington Post, Science Notebook.

    4. 4 A Philadelphia company is using the remnants of cooking grease, the slimy sticky gunk that collects in restaurant drains, usually hauled away for a price to make what useful material? Alternative fuel—Philadelphia Fry-O-Diesel is focused on making biodiesel fuel – NPR, Morning Edition, 12/06/06.

    5. 5 Business Week suggests five wild geo-engineering fixes for dealing with Global warming. Name three. a. Solar shade around the earth, b. Algae farming, c. Cloud factories, d. Moving oceans, e. Salting the seas - BusinessWeek, 11/27/06.

    6. 6 The rice crop futures market was thrown into turmoil when Bayer CropScience of Research Triangle announced in August that the U.S. rice supply had been contaminated with Bayer’s genetically engineered rice LL601. Rice prices have plummeted, exports have been blocked by other countries objecting to “frankenfood” and 300 farmers are suing Bayer. Who does Bayer blame for the mishap? The farmers and “Act of God” - Washington Post, 11/22/06.

    7. 7 Three organizations joined together to form The J. Craig Venter Institute. Name at least two of the three. TIGR (The Institute for Genomic Research), the J. Craig Venter Institute (JCVI) and the J. Craig Venter Science Foundation (JCVSF). The JCVI was renamed The Center for Advancement of Genomics (TCAG). - Press Release from http://www.venterinstitute.org/

    8. 8 Pfizer invested 1 $ billion and lost a potential 15$ Billion in annual sales with its most promising experimental heart drug, Torcetrapib, when it was found to be ineffective. What was it supposed to do? Increase HDL, the good cholesterol - New York Times, 12/5/06.

    9. 9 Why did Torcetrapib fail? Because it caused heart failure - New York Times, 12/5/06.

    10. 10 In a time of all time high cost biotech deals, what new business approach is being taken by biotech’s to license their technologies to large pharmaceutical companies? Using auctions with multiple bidding partners—driving the price of deals up.

    11. 11 New DNA analyzers have been developed which will let scientists study the DNA of what extinct group of human forebears? Neanderthal - Washington Post, 11/16/06.

    12. 12 Neanderthals existed in Asia 45,000 years ago and ended in extinction from Europe 15,000 years later. Evolutionary geneticists will be able to analyze Neanderthal DNA from small fragments of bone, to determine what makes humans unique and different from these “closest to human cousins”. What will scientists compare between Neanderthals and “modern humans”? a. Facility with language i.e. increased brain size and/or appearance. b. Any evidence of interbreeding - Newsweek, 12/11/06

    13. 13 Why is there is a ban on some toy sales in San Francisco? The plastic used contains toxins - San Francisco Chronicle, 11/19/06.

    14. 14 What disease has been recently reported to increase the spread of the HIV (AIDS) virus by boosting the viral load? Malaria has helped infect hundreds of thousands, even millions in sub-Saharan Africa - Washington Post, 2006.

    15. 15 For what two diseases did the local company, Advancis Pharmaceutical, succeed with a treatment in phase three clinical trials? Strep throat and tonsillitis - Washington Business journal, 12/15/06.

    16. 16 How far might some disabled parents go to ensure that their children are genetically similar to them? Using amniocentesis to intentionally choose malfunctioning genes to produce disabilities like deafness or dwarfism - New York Times, 12/5/06.

    17. 17 A substance, derived from a member of the ginger family, aframomum melegueta, and found on the West Coast of Africa, is being investigated as a powerful type of anti inflammatory drug. It would work like Celebrex or Vioxx , but with, hopefully, none of their negative side effects. Observations on the behavior of which species have led to this discovery? Gorilla - The Washington Post, 2006.

    18. 18 16. The D.C. Council has approved $11.5 Million for the design phase of a $200,000. million facility to house the medical examiners office. By 2010, DC will have a lab with an ability that most states already have. What other functions will the lab provide? A DNA forensics lab and a public health, bio-safety level three, lab to test the danger of biological and chemical substances - Washington Business Journal, September 8-14, 2006.

    19. 19 A local doctor, Patrick Melder, whose practice is at Bethesda’s Suburban hospital, devised a new, hand held camera that will transform the way what type of medical test is done? Endoscopies - Dr. Melder’s 9-month old company Envisionier Medical Technologies has raised almost $1 million and has been admitted into the Maryland Technology Development Center incubator in Rockville - Washington Business Journal, September 22-28, 2006.

    20. 20 18. What is the idea behind the formation of CoGenesys Inc. started by Craig Rosen, formerly of Human Genome Sciences, Inc.? The company will become a drug development engine for big pharma, by testing new products long enough to convince big pharma to buy them to fill their pipeline. They are not interested in taking their products through the most expensive testing or in selling drugs to patients - Washington Post, 7/31/06.

    21. 21 19. A Gaithersburg company, GeneDx, was started by its co-founders in 2000 for about $28,000, a discarded desktop computer and two desk chairs. Who recently purchased the company, which develops genetic diagnostics and tests for rare disorders primarily in children, for 17 million in stock and cash? A New Jersey company, Bio Reference Laboratories purchased the company and will leave it in place to develop adult disorder testing - Washington Business Journal, September 8-14, 2006.

    22. 22 What country is pumping $3.5 billion into making its biotech and nanotech sectors among the best in the world? Montgomery County is working hard, more than with any other country, to cultivate and bring new biotechs from this country to Maryland. South Korea - Washington Business Journal, October 27 – November 2, 2006.

    23. 23 What disease is the biggest killer of the world’s children, killing 2 million a year, more than aids, malaria and measles combined? Pneumonia - New York Times, 12/5/06.

    24. 24 22. What is the most common medical mistake, according to the Health Literacy Advisory Board at the American College of Physicians Foundation, causing 530,000 adverse drug events each year, some leading to hospitalization and even death? Medication Error including poorly communicated directions on pill bottle labels. The most common problems associated with medicine error are: the need for more explicit directions, confusing icons on medicine bottles, archaic language used to describe how to consume medicines, lack of patient care in reading labels, and lack of questions for the Dr. and pharmacist about the confusing directions - NPR, “Your Health”, 12/7/06.

    25. 25 23. In early December, in a controversial decision, the FDA affirmed the safety of what new generation product? Drug eluting artery stents, used widely to keep clogged heart arteries open, may increase the risk of potentially dangerous blood clots. However, if used properly, no evidence exists that they boost the likelihood of having a heart attack or dying - Washington Post, 12/8/06.

    26. 26 24. What revolutionary technology allows us to peer into the future, is transforming medicine and the way we think about health? Genetic testing will allow us to understand, diagnose, treat, and predict risk for many diseases in the near future if they are not already available - Newsweek, 10/11/06, p. 53.

    27. 27 25. What is the exact title of the April 17th 6th Annual BIO IT Coalition conference? “The State of Healthcare & Medical Technology in 2020”

    28. 28 “Life Science (Medical) Word Qiuz”

    29. 29 Erlichiosis A tick borne infection caused by the bacterial genus Erlicia. It exhibits flu like symptoms including headache, muscle aches, chills, nausea, and vomiting.

    30. 30 Bissinosis Brown lung disease caused by inhaling dust and fibers from hemp, flax, and cotton processing.  It exhibits asthma like symptoms and could chronic bronchitis and emphysema.

    31. 31 Malleolus One of the prominent bony humps of the ankle.

    32. 32 Strongyloidiasis An infestation caused by the parasite Strongyloides stercoralis occurring In tropical regions.  It exhibits an itchy rash on the feet, stomach pain, nausea, diarrhea, weight loss, dry cough, and a loss of the sense of well-being. 

    33. 33 Tenosynovitis A rheumatoid inflammation of a tendon that includes the synovium (joint lining).  It occurs in areas of small numerous joints such as the hands or feet,

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