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Occupational dosimetry in a PET center due to radionuclide production and medical use

This study investigates the occupational exposure and dosimetry of technicians and nurses in a PET center due to radionuclide production and medical use. The study analyzes the activity produced and used, distribution of 18FDG, procedures performed by technicians and nurses, and the resulting doses received. The findings highlight the correlation between doses received and activity manipulated, and the effectiveness of lead containers and syringe manipulators in reducing personnel dose.

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Occupational dosimetry in a PET center due to radionuclide production and medical use

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  1. Occupational dosimetry in a PET center due to radionuclide production and medical use JM Martí-Climent, I Peñuelas Servicio de Medicina Nuclear. Clínica Universitaria Universidad de Navarra. Pamplona. Spain.

  2. Aim • The occupational exposure due to Positron Emission Tomography (PET) to technicians and nurses is related to their working procedures and workload • activity produced and used • 18FDG activity distributed • PET studies performed • Period: 1996 - 2001

  3. Personnel • Technicians • Dose drawing and preparation • Hot PET laboratory management • Basic cyclotron maintenance • 18FDG Distribution since 1998 • Nurses • Take care of the patient • Inject the dose • Blood pressure monitoring and sampling

  4. Dosimetry • Effective dose • TLD dosimeters: Panasonic UD-802 AR • Deep depth (1000 mg/cm2) • Finger dose • Ring dosimeter: Lithium-7 borate

  5. Results Activity in our PET Center

  6. Results 18FDG used in our Center 85 % of 7032

  7. Mean 414 432 429 420 485 419 MBq Results Mean activity used per PET study

  8. Results 18FDG distributed GBq/package 4.1 10.4 12.0 10.5

  9. Technicians r2 = 0.926 (p<0.002) r2 = 0.997 (p<0.001) Results Collective personnel dosimetry Nurses

  10. Finger dose Results Nurses dosimetry Effective dose

  11. Finger dose Results Technicians dosimetry Effective dose

  12. Dose per activity (mSv/MBq) 0.032 mSv/MBq 0.087 Discussion Nurses normalized collective dose Dose per study (mSv/study) Effective 13.3 mSv/study Finger 35.9

  13. Dose per activity (mSv/MBq) 0.0025 mSv/MBq 0.155 Discussion Technicians normalized collective dose Dose per study (mSv/study) Effective 1.7 mSv/study Finger 123

  14. Discussion Collective dose vs activity managed Nurses Technicians Correlation p<0.002 p<0.01

  15. Discussion Nurses procedures • Lead shield holder with handle for transporting syringe (2.5 cm) • Lead pig for dose injection (5 cm) • Dosimetry depends on • dose injected • periods of time near the patient

  16. Discussion Technicians procedures • Small volume of radiopharmaceutical transferred automatically from module to hot cell • Tracer is drawn up manually into a syringe • Activity is measured

  17. Pneumatic driven system up and down • Remove a sterile filter • Activity measured • With a nipper, vial placed into a 3 cm lead container • Placed into the package Discussion Technicians: FDG package preparation • FDG transferred into a vial placed inside the dose calibrator • Transference stopped

  18. Discussion Dose comparison mSv/study mSv/MBq MBq Efective Finger Efective Finger This study Tech. 1.7 123 0.002 0.155 414 Nur. 13.3 36 0.032 0.087 McCormick, 1993 Qual. 14 Quan. 40 Gonzalez, 1999 Lab 2-14 250 Med 3.9 Chiesa, 1997 WB 5.9 500 2 level 11.5 Benatar, 2000 5.5 0.018 320 Anderson, 2002 7.4 0.019 Zito 8.6 85

  19. Conclusion (I) • For each group a significant correlation exists between doses received and activity manipulated • There is a correlation between effective dose and finger dose • Technicians dosimetry is predominantly due to the activity distributed

  20. Conclusion (II) • Special lead containers and syringe manipulators were designed and proved to be efficient for reducing personnel dose • Basic automation and procedures optimization in the laboratory during the first two years provided safety methods when we started FDG distribution

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