'Ibrutinib' presentation slideshows

BTK inhibition in mantle cell and diffuse large cell lymphoma: the next steps

BTK inhibition in mantle cell and diffuse large cell lymphoma: the next steps. Kristie A. Blum, MD Associate Professor of Medicine Section Head, OSU Lymphoma Program. Discussion topics. Single agent ibrutinib trials Combination ibrutinib trials Prognostic factors in MCL and DLCL

1.09k views • 74 slides

Targeting the Cell Cycle in Lymphoma Therapy Selina Chen- Kiang Weill Cornell Medical College

Targeting the Cell Cycle in Lymphoma Therapy Selina Chen- Kiang Weill Cornell Medical College. CDK Inhibitors. Non-Selective CDK4/CDK6 inhibitors Targeting multiple CDKs, some are transcription factors Flavopiridol CDK9 Daniciclib CDK7 Selective CDK4/CDK6 inhibitors

461 views • 31 slides

Ibrutinib: Analysis of Pivotal Data

821 views • 30 slides

Imbruvica 140mg | Imbruvica 140mg capsules | Ibrutinib 140mg | Ibrutinib 140mg capsules

Imbruvica stops a protein in B cells called Brutonu2019s tyrosine kinase, or BTK. BTK indicating is required for B cells to multiply and survive.

173 views • 15 slides

Brown JR et al. Proc ASH 2013;Abstract 525.

Ibrutinib in Combination with Bendamustine and Rituximab I s Active and Tolerable in Patients with Relapsed/Refractory CLL/SLL: Final Results of a Phase 1b Study. Brown JR et al. Proc ASH 2013;Abstract 525. Background.

285 views • 11 slides

Treon SP et al. Proc ASH 2013;Abstract 251.

303 views • 10 slides

Imbruvica 70mg | Imbruvica 70mg capsules | Apple Pharmaceuticals

Imbruvica 70mg stops a protein in B cells called Brutonu2019s tyrosine kinase or BTK.Imbruvica 70mg is indicated for the treatment following condition Mantle cell lymphoma (MCL) @Myapplepharma

117 views • 10 slides

Imbruvica 140mg | Imbruvica 140mg capsules | Ibrutinib 140mg | Ibrutinib 140mg capsules | Apple pharmaceuticals

Imbruvica stops a protein in B cells called Brutonu2019s tyrosine kinase, or BTK. BTK indicating is required for B cells to multiply and survive.

99 views • 9 slides

Imbruvica 70mg | Imbruvica 70mg capsules | Apple Pharmaceuticals

Imbruvica 70mg stops a protein in B cells called Brutonu2019s tyrosine kinase or BTK.Imbruvica 70mg is indicated for the treatment following condition Mantle cell lymphoma (MCL) @Myapplepharma

76 views • 7 slides

Ibrutinib : First-in Class Inhibitor of BTK

O. N. H. 2. N. N. N. N. N. O. Ibrutinib : First-in Class Inhibitor of BTK. Forms a specific and irreversible bond with cysteine-481 in BTK Highly potent BTK inhibition at IC 50 = 0.5 nM Orally administered with once daily dosing resulting in 24-hr target inhibition

1k views • 6 slides