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Meningococcal Septicaemia

Meningococcal Septicaemia. Dr Nadeem Akhtar 2010. Infectious Agent. Gram-negative diplococci Carried in nasopharynx but not all strains pathogenic Causes meningoccocal Meningitis. Incidence. * Rate per 100, 000 population. Spread. Acquired by direct contact

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Meningococcal Septicaemia

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  1. Meningococcal Septicaemia Dr Nadeem Akhtar 2010

  2. Infectious Agent • Gram-negative diplococci • Carried in nasopharynx but not all strains pathogenic • Causes meningoccocal Meningitis

  3. Incidence * Rate per 100, 000 population

  4. Spread • Acquired by direct contact • Inhalation of infectious droplets. • Crowding and fatigue predispose people to this disease. • The incubation period is 1 to 7 days.

  5. Pathogenesis

  6. Purpuric Rash

  7. Complications • Raised intracranial pressure • Seizures • Shock • DIC

  8. Treatment • Acute – immediate IV/IM antibiotics • Specific antibiotics based on sensitivity of organism • Ceftriaxone • Supportive treatment • Fluids • Nutrition • Anti-epileptic • Rifampicingiven to those exposed

  9. Immunisation • Serogroups A, B, C, W and Y • Vaccine available as part of quadrivalent vaccine (ACWY vax) • Serogroup B • mainly affects children under 4 (peak 6-12 months), now accounts for more than 80% of cases of meningococcal meningitis • NO VACCINE

  10. Immunisation Schedule

  11. Summary

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