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interleukin 15

Interleukin 15 (IL-15) is a cytokine with structural similarity to IL-2. Like IL-2, IL-15 binds to and signals through the IL-2/IL-15 beta chain (CD122) and the common gamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces cell proliferation of natural killer cells; cells of the innate immune system whose principal role is to kill virally infected cells.

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interleukin 15

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  1. IL15 interleukin 15 BackgroundInterleukin 15 (IL-15) is a cytokine with structural similarity to IL-2. Like IL-2, IL-15 binds to and signals through the IL-2/IL-15 beta chain (CD122) and the common gamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces cell proliferation of natural killer cells; cells of the innate immune system whose principal role is to kill virally infected cells. SynonymsIL15; MGC9721; Interleukin-15 precursor; OTTHUMP00000164617; interleukin 15; IL-15 Recombinant Proteins Cell & Tissue Lysates GMP Proteins Protein Reference Standard Cat.# Product name Source (Host) Species IL15-01R Recombinant Rhesus Monkey IL15 Protein, His-taggedYeast Rhesus Monkey His +Inquiry IL15-272H Recombinant Human IL15 protein, Fc/Avi-tagged, Biotinylated HEK293 Cells Human Fc/Avi +Inquiry IL15-321H Recombinant Human IL15 Protein (Asn 49 - Ser 162) Human +Inquiry IL15-382H Recombinant Human IL15 Protein (Asn49-Ser162) E. coli Human +Inquiry IL15-004H Recombinant Human IL15 Protein, His-tagged E. coli Human His +Inquiry IL15-483H Recombinant Human Interleukin 15E. coli Human N/A+Inquiry Il15-484M Recombinant Mouse Interleukin 15 E. coli Mouse N/A+Inquiry Il15-001H Recombinant Human Il15, HIgG1 Fc-tagged, mutant Human Fc +Inquiry Il15-002H Recombinant Human Il15, MIgG2a Fc-tagged CHO +Inquiry IL15-006H Recombinant Human IL15, HIgG1 Fc-tagged +Inquiry IL15-125H Recombinant Human IL15 protein E. coli Human IL15-25H Recombinant Human IL15 E. coli Human IL15-270H Recombinant Human IL15, StrepII-tagged HEK293 Strep II +Inquiry IL15-271H Recombinant Human IL15 protein HEK293 +Inquiry IL15-28238TH Recombinant Human IL15, His-tagged E. coli Human His +Inquiry IL15-306H Recombinant Human IL15, His-tagged E. coli Human His +Inquiry TagPrice E.coli CHO Human Fc CHO Human Fc +Inquiry +Inquiry Human Human

  2. IL15-330H Recombinant Human IL15, Fc-tagged CHO +Inquiry IL15-45H Recombinant Human IL15 protein, His-tagged E. coli Human His +Inquiry IL15-8119M Recombinant Mouse IL15 Protein His +Inquiry IL15-3028RRecombinant Rat IL15 Protein Mammalian Cells +Inquiry IL15-2232RRecombinant Rhesus monkey IL15 Protein, His-tagged Mammalian Cells Rhesus Macaque IL15-20C Recombinant Chicken IL-15 IL15-6140CRecombinant Chicken IL15 Mammalian Cells +Inquiry IL15-863R Recombinant Rabbit IL15 protein, His-tagged His +Inquiry IL15-3624ZRecombinant Zebrafish IL15 His +Inquiry IL15-1099FRecombinant Feline IL15 IL15-263S Recombinant Swine IL15 IL15-80G Recombinant Guinea Pig IL-15 Yeast IL15-859C Recombinant Cattle IL15 protein, His-tagged His +Inquiry Il15-860G Recombinant Guinea pig Il15 protein, His & S-tagged Guinea pig His/S +Inquiry IL15-861S Recombinant Sheep IL15 protein, His-tagged His +Inquiry IL15-532H Recombinant Human Interleukin 15, His-tagged Human His +Inquiry Il15-423M Recombinant Mouse Interleukin 15, His-taggedE. coli Mouse His +Inquiry Il15-533M Recombinant Mouse Interleukin 15, His-taggedE. coli Mouse His +Inquiry Il15-739M Recombinant Mouse Interleukin 15, His-taggedE. coli Mouse His +Inquiry IL15-24H Recombinant Human Interleukin-15E. coli Human N/A+Inquiry Il15-69M Recombinant Mouse Interleukin 15 E. coli Mouse N/A+Inquiry Il15-231R Recombinant Rat Interleukin 15 +Inquiry Il15-88R Recombinant Rat Interleukin 15 IL15-235B Recombinant Bovine Interleukin 15 Yeast IL15-253E Recombinant Equine Interleukin 15Yeast IL15-80P Recombinant Porcine Interleukin-15 Involved Pathway IL15 involved in several pathways and played different roles in them. We Human Fc Mammalian Cells Mouse RatHis His +Inquiry Yeast Chicken +Inquiry His Chicken E. coli Rabbit Mammalian Cells Zebrafish E. coli Feline Yeast +Inquiry Pig N/A+Inquiry Guinea Pig +Inquiry E. coli Cattle E. coli E. coli Sheep E. coli Sf 21 Insect cells RatN/A E. coli RatN/A+Inquiry Bovine N/A+Inquiry Equine N/A+Inquiry E. coli Pig N/A+Inquiry

  3. selected most pathways IL15 participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, TNF signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site. Pathway NamePathway Related Protein Cytokine-cytokine receptor interactionIL12A; IL5RA; IFNAR1; IL7R; CCR8; CD70; IRX1; CRFB2; TNFSF8; CXCL6 Jak-STAT signaling pathwayIL4R; HRASB; IFNA5; GRB2A; PIK3CG; SOCS1A; CCND2; IL11RA; EP300; IL29 TNF signaling pathwayLIF; FAS; NFKBIA; MAP3K5; MAGI2; MAP3K7IP3; RPS6KA4; SELE; CASP7; Ccl12 Intestinal iITGB7; HLA-DRB4; IL6; IL5; HLA-DRA; IL4; TGFB1A; MHC2DAB; ITGA4; CCL27B ne network for IgA productionIL5; HLA-DQA1; HLA-DRB5; CXCR4B; IL-15RA; ITGB7; BMA1; ICOSLG; HLA-DMA; MHC2DAB HTLV-I infectionANAPC1; IL6; CDC23; RB1; RANBP1; ITGAL; CREM; NFATC3; KAT2A; NFATC1 Herpes simplex infectionH2-AB1; EIF2AK1; MHC2DCB; Fasl; OAS2; TAF10; HCFC1A; TAF6; SP100; TAF3 Rheumatoid arthritisIl23a; Il12b; HLA-DRB3; H2-AB1; HLA-DQA1; CD28; ATP6V1E1; HLA-DOA; TLR4; ATP6V0A2; H2-AA Protein Function IL15 has several biochemical functions, for example, cytokine activity, cytokine receptor binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL15 itself. We selected most functions IL15 had, and list some proteins which have the same functions with IL15. You can find most of the proteins on our site. FunctionRelated Protein Function cytokine activityRelated Protein MSTNB; IL34; IL24; IFNK; BMP7A; IL26; IL12BA; LEFTY1; IFNA17; IL1B Function cytokine receptor bindingRelated Protein IFNA5; IL17A/F1; IFNPHI4; IFNPHI2; IL17B; IL17A/F2; IFNPHI1; IL17A; IFNA14; IFNW1 Function protein bindingRelated Protein EIF4G2; DDB1; MICU1; UQCRH; ICAM3; SPOP; MRPL53; FAM124A; KLRB1B; ERBB4 Interacting Protein IL15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL15 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL15. IL2RB; IL15RA; STAT5B; TRAF3; ZNRD1 IL15 Related Articles Krabben, A; Huizinga, TWJ; et al. Biomarkers for Radiographic Progression in

  4. Rheumatoid Arthritis. CURRENT PHARMACEUTICAL DESIGN 21:147-169(2015). Britze, A; Palmfeldt, J; et al. 44-plex cytokine profile of cholesteatoma. ACTA OTO-LARYNGOLOGICA 134:41-50(2014).

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