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Albany Medical Center

Albany Medical Center. Pharmaceutical waste management: A 2 year pilot project Funded by the US EPA grant X9-97256506-0 In collaboration with HANYS (Healthcare Association of New York State) and the New York State Department of Environmental Conservation. Russell F. Mankes, PhD

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Albany Medical Center

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  1. Albany Medical Center Pharmaceutical waste management: A 2 year pilot project Funded by the US EPA grant X9-97256506-0 In collaboration with HANYS (Healthcare Association of New York State) and the New York State Department of Environmental Conservation Russell F. Mankes, PhD Associate Professor, Center for Neuropharmacology and Neuroscience and Center for Immunology and Microbial Disease

  2. MetricsAMC-SCC Formulary characterization

  3. Waste Accumulation • Containers? • Size ? • Number ? • Location ? • Type ? • Liners ? • Liquids ? • Labeling& closures ? • Mounting? 4 gallon compatible Waste container 2 gallon incompatible Waste container

  4. Waste Segregation • Time consuming & Labor intensive – 2 staff members x 15 minutes / container. • High level of training required to identify drugs. • High level of security & regulatory approval for staff by New York State required as controlled substances are commonly found in the pharmaceutical waste bins (despite the label no controlled substances). • Sharps maldisposals into pharmaceutical waste make waste sorting hazardous and PPE is required

  5. Education

  6. Model Education Plan (cont’d) • Outcome: Managers and Directors hold staff accountable for incorporating change into practice. • Metrics: • Post test – 80% minimum passing. Completion rates for each job title, 99% target rate. New hires must receive training at hire. • Random trainee follow-ups. Correct response rates below 80% trigger retraining.

  7. Preliminary Results • 5/9/08 – 9/10/08 (118 days) • 40 containers from 8 OR’s Post-Op; Pre-Op, MRI, Patient care floor and a Surgical practice site • 0.04 lbs/container/day • Total weight 188.2 pounds • 4.6 pounds RCRA • 168.2 pounds Non-RCRA • Propofol most common (28%) non-RCRA medication • 250 sharps • 147 Antibiotics (3.9 pounds) • 75 Controlled substances (1.0 pound) • Costs per pound (RCRA contractor): • RCRA pharmaceutical waste $156 - $3.52; • RCRA chemotherapeutic waste $6.07; • Non-RCRA pharmaceutical waste for incineration only $4.37 – $2.23. • Stericycle = $0.36/lb (Incinerate only). • 20 hr for labor in waste sorting (2 persons [1 PhD, 1 BS] * 0.25 hr per container)

  8. Preliminary Results (cont’d)

  9. propofol lidocaine succinylcholine bupivacaine ephedrine Sensorcaine-80%cumulative percent lidocaine-epinephrine epinephrine-NYS RCRA marcaine proparcaine atracurium polocaine atropine vancomycin-Ab mepivicaine/marcaine/hydase lidocaine jelly Dye-RCRA edetate heparin gonak glycopyrrolate betadine Ondansetron – Eco Hazard labetalol bacitracin-Ab dexamethasone fentanyl-CS midazolam-CS neostigmine xylocaine/marcaine ancef-Ab cefazolin-Ab neomycin ointment-Ab gentamicin-Ab phenylephrine brimonidine solumedrol ketorolac lincomycin-Ab tetracaine ceftazidime-Ab cyclopentolate diphenhydramine Preliminary Results (cont’d)Typical drugs collected:

  10. Preliminary results (cont’d) Process Improvement – Propofol (Diprivan®) Propofol is an injectable anesthetic agent used for outpatient or inpatient surgical procedures or to provide conscious sedation. It is a suspension in liquid supplied in 20, 50 or 100 mL vials. It is considered a 9 of 9 for persistence, bioaccumulation and toxicity (Environmentally classified pharmaceuticals, http://ww.janusinfo.se). During waste segregation, propofol was found to comprise 29% of the total waste generated from the operating rooms as for each case required a new vial of propofol to be opened and all propofol from the preceding case to be discarded. Solution: 50 and 100 mL vials of propofol were removed from AMC Pharmacy inventory. Propofol would only be available in the smallest size manufactured to reduce wastage.

  11. Problem Areas • Security & Controlled substance disposal, e.g., Chloral Hydrate & Paraldehyde RCRA & DEA Regulated, “wasting” of narcotics into toilet, sink. • Pain Management, HIV Medicine have a medical need to verify patient disposal of excess pain medications • Diagnostic Radiology – Barium Waste • Mixed Wastes (vaccines)

  12. Contact Information • Russell F. Mankes, PhD, Assoc Prof, MC-96, Albany Medical Center, 43 New Scotland Ave, Albany, NY 12208 • Telephone: 518-262-5490 • To request PDF documents of presentation or supplementary information, e-mail request to MankesR@Mail.AMC.EDU

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