Can Fatty Liver Disease Be Treated - ACRI India

1. Fatty liver is a disease that involves the buildup of excessive fat in the liver, which leads to not only obesity, but many other health problems too. The liver is the largest internal organ, which is responsible for a wide range of functions, like filtering the blood, and processing all that we eat and drink. Fatty liver is the ailment that is considered to be a problem when the proportion of liver cells that contain fat goes beyond 5%. The main reason for fatty liver disease is heavy drinking of alcohol. However, for those who don’t drink alcohol and are yet a victim of fatty liver, the reasons could include heavy body weight, high sugar diet, diabetes, low physical activity, and high triglycerides. Basically, the ailment develops when the body creates too much fat and can't metabolize it efficiently enough, which results in the excess fat being stored in the liver cells. Fatty liver results in liver inflammation, fatigue, abdominal discomfort, poor appetite, weight loss, and weakness. However, if the condition worsens, it may lead to severe problems like liver failure, abnormal bleeding, and jaundice in the skin and eyes. While there has been no particular solution to the fatty liver disease yet, except changes in the diet and lifestyle being advised by doctors, Israeli researchers have now discovered 27 new molecules that may lead to a potential treatment for the ailment. These findings have been led by Professor Amiram Goldblum at the Hebrew University of Jerusalem. The research has been possible by a new algorithm, which chose 27 molecules with the strongest therapeutic potential

2. from a database of 1.56 million molecules! These 27 molecules are now undergoing pharmaceutical evaluations to treat the incurable fatty liver disease, activating a special protein called PPAR-delta. This protein has the potential to increase physical stamina and reduce waistlines by getting muscle cells to burn more fat. These future evaluations are also going to hopefully include testing treatments for improved wound healing, and to prevent kidney toxicity in diabetics. These 27 molecules that have been found by Goldblum have become a big talk today. Hebrew University’s Biotech company, Integra Holdings, has determined that 21 out of the 27 molecules have the potential to reach pharmaceutical success. Furthermore, Israel's Heller Institute of Medical Research is also testing PPAR-delta's physical endurance properties on mice. We will now have to wait and watch what comes out of these experiments. However, Goldblum predicts that in a few years’ time, we will hopefully see several of these molecules in the pipeline for clinical studies on humans. You can also make your country proud by getting involved with such clinical research studies to find new treatments and medical devices for all kinds of old and new ailments. For this, you will have to take up a course from Avigna Clinical Research Institute, one of the best clinical research institutes in Bangalore, where you will be educated about every aspect of clinical research by learned professionals. You will earn a legitimate certification that can not only help you build up a great clinical research career ahead, but will also help you gain the satisfaction of serving the people of your country with the best healthcare treatments.