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Syphilis is a sexually transmitted disease. A common cause of the genital ulcer.<br>Read more from here: https//www.doctorsmediainfo.com
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Syphilis: test, treatment, symptom https://www.doctorsmediainfo.com/2020/08/syphilis.html
Syphilis is a sexually transmitted disease. It is caused by treponema pallidum.
The infection is characterized by primary, secondary, and tertiary stages. The incubation period is between 9-90 days. Usually, a person presents with a sexual intercourse history of months back and painless ulcer in early syphilis.
Syphilis symptoms: according to time syphilis has 3 stages, • Primary stage • Secondary stage • Tertiary stage
Primary feature: • A painless ulcer at the site of sexual contact. • Local lymph node enlargement which is painless • Often women present with an ulcer in the cervix
Secondary feature: Occurs 6-10 weeks of the primary feature • The patient may present with fever, lymph node enlargement • Rash on the trunk, palm, and soles
• A characteristic ulcer in the oral cavity known as snail track ulcers. Found in 30% patient. • Painless, warty lesions of skin and bones are known as condylomata lata.
Tertiary features: • A granulomatous lesion of the skin and bones are known as gumma • Tabes dorsalis • Argyll robertson pupil (A characteristic pupil found in tertiary syphilis )
Syphilis test Nonspecific tests • VDRL (venereal disease research laboratory ) test • RPR ( rapid plasma reagin) test
• SPECIFIC TESTS • EIA For IgG And IgM • TPHA ( Treponema Pallidum Hemagglutination Test ) • TPPA • FTA-ABS
A most common screening test is the VDRL test. It is non- antigenic and specific. It gives a false positive and false negative test. Most common used specific test is TPHA
Syphilis treatment Penicillin is the drug of choice. Currently, A single dose of 2.4 mega units of intramuscular benzathine penicillin is used in early syphilis (less than 2 years). Where three-dose in a weekly interval is recommended for late syphilis. In pregnancy, penicillin is the drug of choice.
Follow up Resolution of signs occurs after 6 months with proper treatment. VDRL TEST becomes negative within 6 month in primary syphilis.12 -13 months need for secondary syphilis. Specific treponemal antibody tests may remain positive for life long.
Prevention Safe sex practices can prevent syphilis and other sexually transmitted diseases.
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