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The 10 Most Advanced Medical Device Companies [ Business Magazine ]

Insights Success has come up with the issue of u201cThe 10 Most Advanced Medical Device companiesu201d. Here we have tried to focus on the different business portfolios with unique service solutions,<br>

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The 10 Most Advanced Medical Device Companies [ Business Magazine ]

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  1. www.insightssuccess.in I I VOL 3 10 MOST ADVANCED MEDICAL DEVICE COMPANIES THE March 2019 THE ISSUE 1 Company Of the Month Samuel Williams George, CEO GESCO Healthcare Editor’s Choice Cleaning and Disinfecting Services of Medical Devices BioTalk Applications of Biomedical Devices for Controlled Drug Delivery Balasubramaniam M Chief Executive Officer CURA Healthcare Delivering High Performance, High quality solutions in most affordable way

  2. Editor-in-Chief Pooja M. Bansal Managing Editor Devasish Kanojiya Executive Editor Shruti P . Jambhale Art & Design Head Amol Kamble Associate Designer Poonam, Shweta Art & Picture Editor Rahul Kavnekar Co-designer Mayur Koli Business Development Manager Akansha Garewal Sales Executives Tarun Singh, Asif Patel Technical Head Swapnil Patil Technical Specialist Amar, Pratiksha Digital Marketing Manager Prashant SME-SMO Executives Swati, Manoj Circulation Manager Tanaji sales@insightssuccess.com March 2019 Corporate Ofces: Insights Success Media and Technology Pvt. Ltd. Off. No. 513 & 510, 5 Flr., Rainbow Plaza, Shivar Chowk, Pimple Saudagar, Pune, Maharashtra 411017 Phone - India: +91 7410079881/ 82/ 83/ 84/ 85 Email: info@insightssuccess.in For Subscription: www.insightssuccess.in Insights Success Media Tech LLC 555 Metro Place North, Suite 100, Dublin, OH 43017, United States Phone - (614)-602-1754 Email: info@insightssuccess.com For Subscription: www.insightssuccess.com th Cover Price : RS. 150/- https://twitter.com/insightssuccess Follow us on : www.facebook.com/insightssuccess/ Copyright © 2019 Insights Success Media and Technology Pvt. Ltd., All rights reserved. The content and images used in this magazine should not be reproduced or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without prior permission from Insights Success Media and Technology Pvt. Ltd. Reprint rights remain solely with Insights Success. Printed and Published by Insights Success Media and Technology Pvt. Ltd. RNI NUMBER: MAHENG/2018/75953

  3. From the Editor T industry. oday, the medical devices are driven by innovation and technologies, boosting an unparalleled growth and advancement in the healthcare services With the technological advancements and revolutionary changes in the medical devices, manufacturers and healthcare service providers have started offering personalized patient care and access to complete end-to- end medical device products and services. The new-age medical technology has totally transformed the way of interaction between doctors and patients. The gradual shift from traditional methods to the smart medical devices, right from obtaining real-time information, tracking past health records, identifying potential health issues, to suggesting a treatment, the process has completely improved at its best. Emerging medical device technologies are driven by the Internet of Things (IoT) and are equipped with wireless communication technologies such as Bluetooth and internet connectivity to facilitate machine-to-machine communication. And, the interconnectivity between these modern gadgets with cloud-based platforms is the next step towards the future of medical devices that capture, store, and analyze patient data and health information. These processes will enable remote patient monitoring, previous medical prescriptions tracking and patient locations, patient progress monitoring, and providing access to caregivers. Emerging Technologies: Shaping the Future Medical Devices By observing the overall scenario, it can be concluded that the technological trends and opportunities in medical devices are promising to revolutionize the operations of the healthcare providers and the medical device companies. Shruti Jambhale Shruti P . Jambhale

  4. 08 COVER STORY CURA Healthcare Delivering High Performance, High quality solutions in most affordable way 16 ARTICLES COMPANY OF THE MONTH 20 BioTalk Applications of Biomedical Devices for Controlled Drug Delivery 30 GESCO Healthcare Transforming Lives with Innovative Healthcare Solutions Editor’s Choice Cleaning and Disinfecting Services of Medical Devices

  5. 24 C O N T E N T S 22 GC India Dental A Pioneer behind the Art & Science of Creating Healthy & Beautiful Smile Tech-Facts How Technology is Reshaping Medtech? 36 Jainitri Innovations Developing sustainable technology for saving lives at birth 28 MedTech Spotlight Latest Technologies in Diabetes Vinod Medical Systems 32 Pvt. Ltd. Emphasizing on Customer Satisfaction through Quality Products

  6. THE10 MOST ADVANCED MEDICAL DEVICE COMPANIES The Changing Face of Medical Device Industry edical device industry is one of the crucial and fastest growing industries and the strongest arm of the life M facilities. Today, many companies have made noteworthy technological advancements and grown exponentially. Despite the challenges like heavy regulation and financial pressures on the industry, the market is increasing day-by- day. sciences industry. Medical device companies producing wide range of products such as diagnostics, surgical instruments, and cardiac devices which are used extensively in hospitals and other healthcare This month, Insights Success has come up with the issue of “The 10 Most Advanced Medical Device companies”. Here we have tried to focus on the different business portfolios with unique service solutions, and CURA Healthcare has grabbed our attention most to become the Cover story of this magazine. CURA Healthcare is manufacturer and supplier of world class Imaging Diagnostics and Critical care products. We have also focused on different companies those have come up with unique solutions and GESCO Healthcare stood as Company of the Month. It is a leading Medical device company which endeavors to alleviate pain for patients across the globe, strives to serve quality surgical instruments and implants. Apart from this, we have chosen Arthron which develop, produce and market orthopedic products of paramount precision with state of the art machinery. GC India Dental produces more than 600 different dental products worldwide and thus covers the entire area of consumable materials, devices and equipment for the dental practice and the dental laboratory. Harsoria Healthcare Pvt. Ltd is serving world markets through innovative and revolutionary product designs, with the overall objective of providing full value to its global customers. Jainitri Innovations develops sustainable technology to improve maternal and child healthcare. Medsource Ozone Biomedicals Pvt. Ltd. provides a comprehensive range of diagnostic solutions with excellent quality to price ratio. Monitra Healthcare Private Limited is a Hyderabad based med-tech company developing solutions that capture cardiac events anytime anywhere. TejcoVision is an innovator and supplier of high quality, correctly-styled specialty medical products, and disposable instruments for dermatology & Hair restoration. Vinod Medical Systems Pvt. Ltd. is dealing in high quality Healthcare Imaging, Accessories & Equipments and Photographic products. This magazine also includes leaders’ thoughts as well. Vipul Jain is the CEO at Mirage Group, Advancells, discusses on the topic “How Technology is Reshaping Medtech?” and Dr. V. Mohan, the Chairman and Chief of Diabetology at Dr. Mohan’s Diabetes Specialities Centre highlights his views on the “Latest Technologies in Diabetes”. The editor’s thoughts are also part of this magazine where they have researched on topics like Applications of Biomedical Devices for Controlled Drug Delivery and Cleaning and Disinfecting Services of Medical Devices. So, flip the pages of our magazine and explore interesting insights into the world of business!

  7. CURA CURA Balasubramaniam M Chief Executive Officer

  8. THE10 MOST ADVANCED MEDICAL DEVICE COMPANIES Cover Story WE WILL CATER TO ‘‘ THE GROWING NEEDS OF OUR CUSTOMERS ‘‘ WITH A BREADTH OF HIGH TECHNOLOGY, HIGH PERFORMANCE & COST-EFFECTIVE SOLUTIONS Healthcare Healthcare Delivering High Performance, High quality solutions in most affordable way

  9. T cardiovascular conditions is increasing. The increasing geriatric population along with the sedentary lifestyle is further facilitating the incidence of these chronic diseases. With the rising number of cases, the demand for diagnostic imaging systems is expected to grow as these systems help in early detection of the diseases. resources,” says Balasubramaniam. The biggest strength of CURA as claimed by the company are their employees. “They are the most passionate bunch of people who truly believe that they are part of a chain of “saving lives”,” asserts Balasubramaniam. This relentless pursuit of excellence by the team is aiding them in facing everyday challenges with smile and positivity. “One of key-value we drive in our team is to “Aspire for excellence” and bring your best to achieve these ongoing challenges and meet the rising customer expectations,” adds Balasubramaniam. he prevalence of chronic diseases pertaining to respiratory, brain, and Moreover, the company has also been awarded multiple Quality council awards and Innovation awards and Export promotion awards from Govt. of India. CURA is ISO 13485 certified company and its key products are CE certified by TUV, Germany. Leading with Excellence Balasubramaniam M,the Chief Executive Officer of CURA Healthcare from 2014 and been the driving force in turning around CURA Healthcare into one of the fastest growing Indian Imaging company. CURA Healthcare has grown by over 6 times in the last 3 years. Cognizant of this fact, CURA Healthcare delivers affordable, reliable and confident end-to-end solutions for diagnostic imaging, cardiac and critical care segments through a wide range of product portfolio. Started in 2001, CURA has grown up on value chain to hold a strong presence in India and select markets of Asia and Africa. As an established brand in Diagnostic Imaging, CURA has the most comprehensive suite of Imaging products ranging from X-ray to MRI to mammography to Ultrasound, Imaging Accessories. Innovative Products and Services CURA recently launched an innovative product, which they truly believe will be the beginning and hopefully an integral part of diagnosis to one of the most deadly diseases for women, the Breast cancer. While early screening can prevent and save lives, the currently available method of breast screening are intimidating women with pain, fear of radiation and its side effects, and not to mention the embarrassment of exposure. Before taking the leadership role in CURA Healthcare, Bala was the Regional Director in GE Healthcare based at Singapore and was responsible for the P&L of ASEAN region. He also led the Global transformation initiative for the Asia Pacific region of GE Healthcare. Before moving to Singapore, Bala was the Vice President, South Asia in Wipro GE Healthcare. He has also lead several senior leadership roles in his long career with GE Healthcare and has expertise in managing P&L’s in emerging markets of APAC With a state-of-the-art indigenous manufacturing facility in both Chennai & Chandigarh, and an R&D facility in Chennai, are the two major platforms that are driving CURA’s plans to become one of the top medical equipment player with emerging market relevance. Over the past few years, CURA has grown by 6 times in scale and improved in its value chain from the best-in-class after-sales service provider to a manufacturer and an innovator. CURA has an employee strength of over 400 and has installed over 10,000 diagnostic imaging and critical care units across India along with its after-sales service support of 97.5% uptime, which is at par with global standards. CURA took up this challenge 4 years back and identified the best technology to address this unmet clinical need with a solution, which women would find friendly with no pain, no touch, and no radiation along with dramatically improved accuracy. They launched this innovative productIllumina 360 Digital Robotic Breast Thermography System – 1st of its kind in the world; later awarded for best innovation in Healthcare this year by Department of Science & Technology, Government of India. While many factors influence culture, the single most important one is what leaders do and say on a daily basis. “A crucial step to maintaining a winning culture is to build a cohesive leadership team aligned around a common vision and expected behaviors with the determination and willingness to make culture a top priority throughout the growth journey without compromising on value & compliance,” says Balasubramaniam. Rising above Challenges Started in 2001, CURA has now grown to more than 400 employees, with a management team that represents some of the most experienced professionals in the healthcare industry. “As any company of our size in the MSME sector undergoes a lot of challenges in multiple areas and as a team we have to overcome these challenges with limited Illumina 360 was granted a US patent for its women-friendly design, which can make the invisible early breast tissue changes visible. Illumina 360 is designed and developed in India. CURA was also highlighted at the Arab Health 2018 by Khaleej Times as “ Top 6 innovations to watch out” globally. They believe that Illumina 360 Breast Thermography system can CURA has received multiple accolades in the area of Diagnostic Imagining. It has received the prestigious Product Innovation Award from Frost & Sullivan for their Digital Radiography equipment and Service Excellence Award from Brands Academy.

  10. ‘‘ CURA has chosen both the Technology Transfer and the Distribution route to become a reliable and cost-effective player through strategic partnerships ‘‘

  11. execute well, you have wasted the resources,” advice Balasubramaniam. revolutionize the way breast health is being screened today in India and all other emerging markets of the world. CURA has plans to launch many more revolutionary technologies in imaging diagnostics and critical care segments. CURA is also betting on investing in core technology in Imaging. Balasubramaniam believes that while execution is the most critical success factor, most leaders take it as subservient to strategy and they feel it is best delegated to next level of organization. Simple steps and building blocks of execution for the leader is to stay closer to reality, focus on top few priorities and deliver, Insist on outcomes and not an activity, time is an important dimension, communicate and communicate, get the right people for the job, coach & reward, manage stakeholder expectations. Build trust and it is all about execution to be the winner. Inspirational Values CURA is an institution-driven and professionally managed company that places a high focus on driving strong customer relationships by delivering lower cost of ownership and maximizing the lifetime value. They cater to the growing needs of their customers with a breadth of high technology, high performance & cost effective solutions of “Affordable Luxury” delivered through their own design and development at their state- of-the-art manufacturing facilities and by collaborating with global medical technology corporations and leading research institutes. Putting the Right Foot Forward CURA is expected to grow at 40% annually and they have plans to be an INR 500 Cr company in 3 years. In such a high growth environment, managing the culture is absolutely critical for sustained growth and employee engagement. Balasubramaniam emphasizes the following from his leadership team. One of the key factors of leadership is to demonstrate “Walk the Talk” and “Transparent Communication”. THE BIGGEST STRENGTH OF CURA IS OUR EMPLOYEES, THEY ARE THE MOST PASSIONATE BUNCH OF PEOPLE WHO TRULY BELIEVE THAT THEY ARE PART OF SAVING LIVES At CURA, they strongly believe that India will follow the same path as China wherein many local manufacturers of medical equipment have emerged over the past decade and has built business of large scale & global presence. With the Indian government focusing to boost manufacturing sector in India and with CURA’s strong management team who have worked in large MNCs and executed in global markets, and with a strong distribution and best in class service infrastructure, CURA is well positioned to capitalize this lifetime opportunity. At CURA they believe that communication is an important aspect as it’s extremely critical that all employees have a holistic view of the business in its current state and future vision. As they have grown through acquisitions and new teams coming on board, it became necessary to implement more formal communications vehicles to reach all of their employees who are located in over 23 locations in India & abroad. Expert’s Advice to Budding Entrepreneurs “One of biggest advice I got when I was managing a large business and also when we started the entrepreneurship journey, is to focus on Execution. Many times, we get carried away by great ideas. While Great ideas are important, success happens only on execution and 70% of execution failure is due to poor delegation by leadership. No matter how good is your idea, if you don’t Furthermore, they have initiated bi-monthly company-wide teleconferences “Let’s Talk” sessions to keep employees tapped into the company’s pulse and informed about the bigger vision. These engagement opportunities provide a good outlet for celebrating success, share best practices across the company, as well as an excellent platform for getting employee feedback & suggestions.

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  13. Company of the Month W clinical trials, outsourcing, telemedicine, medical tourism, health insurance and medical equipment. The beginning of the year 2018 has witnessed a lot of trends emerging in the healthcare industry. Technology has been a major player in contributing to the upliftment of this industry. GESCO Healthcare: Innovative Healthcare Solutions ith the rise inrevenue and employment, healthcare has become one of India’s largest sectors comprising hospitals, medical devices, Many corporates as well as the startups are being at the forefront of innovation by combining technologies like AI and machine learning with traditional practices in the healthcare. Acknowledging the current market position, they are climbing the stairways of digitization and transparency, thereby providing innovative solutions in order to revolutionize thehealthcare ecosystem. It is witnessing rapid changes with the strengthening coverage, services and increasing expenditure by public as well as the private players. Transforming Lives with Currently, the company has over 350 employees and its marketing offices in 15 cities all over India and an exhaustive dealer network in the country. It also has a global presence in over 30 countries. Accuracy, Precision and Perfection are the words which make the foundation of the healthcare industry. These are the words on which our lives depend on. It is one such sector where only a minute mistake can cost hundreds of human lives. Whether doing the diagnosis of a disease, a critical surgery, prescription of medicines, usage of pharmaceutical devices, medical tools or operating other complex systems, there has to be accuracy, a conscious, careful and responsible mind which cannot afford to make any mistake. One such company which is transforming the lives of human beings every day with its innovative, yet accurate, precise and perfect healthcare solutions to alleviate pain among the patients globally is GESCO Healthcare, a trailblazer of quality implants and surgical instruments. Instilling Core Values for Improved Efficiency To enhance the performance of the company and increase the efficiency of its services, GESCO Healthcare fosters certain core values among its specialists in the entire team and they are: Innovation through Collaboration The company constantly tries to outdo itself in creating healthcare products that help people live active lives. It leverages the collective genius minds of the medical community to develop innovative solutions for quality healthcare possible every day. Delivering Quality The company claims to have an obsession with quality and that is what makes the GESCO Healthcare stand tall and win countless international accreditations. This dedication towards quality does not get restricted to its products, but goes beyond that - ingrained in all their ethos, infrastructure and teams. Nurturing Relationships “We believe we are better together,” claims GESCO Healthcare and that is why the company deeply invests in its relationships with the medical community, its employees and partners, so as to proper their journey towards re-imagining and re-defining healthcare. · · With a mission to become one of the Top Healthcare Brands globally, GESCO Healthcare, more than half a decade old company, is making enormous efforts to alleviate pain for patients across the globe. The company primarily focuses on the Manufacturing of high-quality Neuro, Orthopedic and Spinal implants along with a wide array of high standard surgical instruments. For its extraordinary services the company has won numerous accreditations including the ones from Indian FDA, ISO 13485, 9001, CE marking, US FDA, and WHO-GMP among many others. · 16 March 2019

  14. SamuelWilliamsGeorge CEO “We always consider our customer database as precious, and we continuously strive hard to satisfy their needs” 17 March 2019

  15. Indian industry of surgical instruments was in its primitive stage, hence, most of the instruments used then were imported, making it was unaffordable. Seeing the potential of the market and demand of the surgical instruments at a reasonable price, Mr Theodore George entered into the scenario and founded GESCO Healthcare in the year 1962. more value to its stakeholders, the company has added new divisions in the niche market including Natural Remedies and Pharma. GESCO also takes initiatives to provide workshops and training programs to surgeons and paramedical teams. Implanting Trust Trust being the foundation of any relationship, the company dedicatedly instills that among each of its employees and every relationship that is anchored with honesty and integrity for delivering effective medical solutions that persistently raise the bar of ethical healthcare. · Fast-tracking with Time Healthcare sector will always have opportunities coming by and GESCO Healthcare is planning to hold its ethics and deliver the same quality in the near future. The organization aims to reach newer heights of success and establish itself as a one-of-its-kind brand. It is embracing the cutting-edge technology and focusing to quench every single healthcare need with its motto never follow always lead pushing the boundaries to challenge the limits. Later in the year 1980, the eldest son of Mr Theodore George, Mr Samuel Williams George, the current CEO at GESCO Healthcare, joined hands with his father as a young engineer to take the company to the level-next. Observing the gap in the market and demand for standard quality Spinal Implants at affordable prices in the early ‘90s, Samuel used the company’s rich experience in Research and Development, cutting-edge machinery, inherent focus on quality and innovation to enter the industry in a new form and create a mark within the minds of medical practitioners. About the Extraordinary Solutions Offered by the Company With its vision, enormous effort, and extraordinary offerings in an unbelievable price, GESCO Healthcare has become one of the most advanced medical device manufacturing facility in the country. Even after manufacturing the products, the company ensures rigorous quality checks at several stages and sterilizes with the help of an exhaustive microbiology laboratory. The company has several patented products and collaborates with numerous major companies of the world in the sector of Neurosurgical and Orthopedic specialties. Some of its products like GAAS and Halifax Nail are highly acclaimed and used all over the world. Footsteps towards Future The company is striving to emerge as a leader in the medical world by innovative enhancement of products, constant evolution of processes and providing value added services. Like any other successful company, GESCO Healthcare too constantly updates itself about the latest happenings in the industry. To take this process a step further, the company provides Continuous Medical Education (CME) about its existing and new products in a regular frequency enabling them to update their existing customer base and build new clientele. To conclude with the USP of the company, Mr Samuel says, “We always keep the value of our customers. Each customer is unique to us and we make strong bonds with each of them. Hence we manufacture unique products for specific customers.” A Strong Team makes a Strong Company and Eventually the Success Point In whichever field it is, a growing team with the continuous hunger for learning and understanding the market trends and the ability to contribute to a team is the most crucial thing for a company’s success. This is what defines GESCO Healthcare and helps them to deliver the highest value to its customers. It has a strong involvement in the field of research in medical science to develop new techniques in diagnosis, treatment and surgical procedures. Innovation being one of the major objectives, the research and development team works constantly on designing new products. With a vision towards diversifying sections, adding The company makes every effort to deliver the best quality products and to achieve that the company compromises nothing. To produce the highest standard of medical equipment in the world, the company invests huge amount resources in highly advanced capital machineries from Switzerland, Germany, Japan and the USA. About the Inception of this Spectacular Company Like all other industry, even healthcare sector suffered a lot after the Indian independence. It was then when the 18 March 2019

  16. APPLICATIONSOF BIOMEDICAL DEVICES FOR CONTROLLED DRUG DELIVERY DRUG DELIVERY iomedical microdevices are fabricated on the order B microchannels to microtranslucers and microelectromechanical systems (MEMS). Biomedical microdevices offers key advantages for applications in health i.e. they are extremely small in sizes; provides invasive procedures; have lower power consumption; high reproducibility and the low costs per device. In addition, they also offer better compatibility and multiple functionalities with integrating electronics. This technology has proliferated the development of variety of microdevices such as micro components of pacemakers, micromedical devices, diagnostic devices, and drug delivery systems. This advent of technology has provided significant improvement over numerous chronic and no chronic illnesses. It has also transformed the way drugs are administered into the patients’ body. These microdevices are based on structural micro parts such as microchannels that stores drugs. In conjunction, MEMS devices incorporated with microacutuators, microsensors, and microtransducers improve the device capabilities. Drug delivery through MEMS provides improved diagnosis, monitoring, and treatment of illness. It also has the ability to control the rate of drug released to the target area. Programmed with continuous delivery alongside the ability to release drug locally increases the treatment efficacy reducing systematic concentration levels and toxicity. Passive microdevices used for drug delivery do not rely on actuation mechanism. These devices are reservoir based and rely on mass transfer across permeable membrane to deliver drugs. The release rate of the drug can be controlled by: of one to hundred µm. These devices are fabricated with critical features and range in complexity from • Effective permeability of membranes by fine-tuning material and structural dimensions • Osmotic pressure • Rate of degradation of polymer contained in the reservoir • Diffusivity properties of the drug One major thing to note here is that the delivery of the drug cannot be modified after implementation. Other passive release devices are based on internal body conditions like the pH or the temperature. Passive Nanochannel-based Drug Delivery Devices These devices were created to improve patient adherence towards chemotherapeutics and quality of life, eliminating the need for repeated administration and regular visits to the clinic. These control the release of the drug by physical- electrostatic confinement and are consist of 30 µm wide microchannels that connects the reservoir. Clinical application- Diabetes, Melanoma, Prostate cancer Active devices use different mechanisms to release drugs in the body and provide increased level of control. These devices can be customised to treat a wide range of diseases requiring specific drug delivery profiles. When compared, MEMS can be activated and can be stopped at any time after implantation. Common miniature power electronics are required by these active devices, which typically increases the overall form factor. Classification Drug delivery system can be classified into two types; passive and active. 20 March 2019

  17. BioTalk Electrothermally Actuated MEMS Drug Delivery Microchip This type of device delivers drugs in a pulsatile manner and because of such, several works on active drug delivery devices based on MEMS have made substantial progress towards treating ailments. Clinical application- Cancer Some other devices are Micropump MEMS-based drug delivery system; Transfermall MEMS; Microneedle Patch Array Delivery System; Electrothermal MEMS drug delivery Device; Microfuluidic Hydraulic MEMS-based devices. Clinical application - Osteoporosis The next generation of delivery models are present in today’s inter-connected world. The current development of such delivery systems is at early stage and even some technologies are still in conception phase. From clinical standpoint, if such clinical needs do exist and is identified, many such applications will demand large payload that cannot be accommodated within the microdevices. Passive and active devices can be a part of invasive procedures and have the ability to enhance the efficacy while reducing the toxicity of the drug. These devices offer a wide range of application with tailored local release and high adherence prerequisites. They also represent a novel technology but also face different regulatory challenges. They also represent the next generation of platforms for more accurate and efficient drug delivery. Such novel platforms promise the patients to increase adherence and overall better treatment outcomes. Rapid-delivery Microchip for Acute Clinical Conditions This device consists of a membrane, actuation, and reservoir layer. Membrane layer consists of biocompatible silicon nitrate and the actuation layer of three micro resistors. On passage of current through resistors, heat is generated and increases the inside pressure of the reservoir. This lead to the rupture of silicon nitrate membrane, followed by the release of the drug. Clinical application- Hemorrhagic Shock Magnetically Control MEMS Delivery A magnetic MEMS drug delivery device was developed for the controlled release of chemotherapeutic agent. In this device, pressure in the reservoir is built, enabling the drug to diffuse out. 21 March 2019

  18. THE10 MOST ADVANCED MEDICAL DEVICE COMPANIES GC A Pioneer behind the Art & Science of Creating Healthy & Beautiful Smile India Dental: N ew technology and innovations are making the human life much easier than before. In today’s fast-paced evolving world, particularly the medical & healthcare industries are continually compelled to develop new and creative ways for human welfare. There can be no medical progress without technological development, and there is no “Healthy Future” without innovations. material. However, it was precisely these difficulties that led to unforeseen changes of direction and turning points that would later be crucial for the long-term success of the company. Now, what started 95 years ago as a small laboratory in Tokyo, Japan, has become a global company that is committed to contributing the people’s oral health around the world in 100 countries. The philosophy of highly valued corporate quality (including products and services), catalyzed by the consistent customer-oriented efforts and the legacy have been brought to India by another Visionary Leader Dr. Sriram Mudambi , Managing Director Dental. He is an amalgamation of sorts who is familiar with five Indian languages. Dr. Sriram was born in Delhi and raised in Hyderabad, graduated in Dentistry from Bangalore. After completing post graduation in Restorative Dentistry from the National University of Singapore, Dr. Sriram was offered to start the Indian Operations for GC, convinced by his several material science research with GC restoratives. Fulfilling all the approaches, GC is standing tall for almost a century with the mission statement: “to improve the dental health of patients around the world with high-quality dental products”. GC is going to celebrate its 100th anniversary in 2021.This mission has not been changed over these years. They constantly upgrade themselves to reach the patients with innovative, high-quality and minimal-intervention products. GC India of GC India, the Asian Subsidiary of GC Corp has internalized GC’s belief & philosophy and is committed to the development of significant innovative technologies, ideas, and concepts in the healthcare sector. GC produces more than 600 different dental products worldwide and thus covers the entire area of consumable materials, devices and equipment for the dental practice and the dental laboratory. Over the years, he has been interested in management and graduated from the prestigious Indian School of Business with the PGPMAX program. An avid audiophile, musician and a lyricist Dr. Sriram with his strategic thinking, business outlook and thorough subject knowledge has brought a rapid growth of GC in India. Visionary Leaders Ensuring the Company’s Growth GC was found in Tokyo during the hard time of great depression in 1921 by a young chemist Kiyoshi NAKAO with his two friends ENJO and Tokuemon MIZUNO. The three founders had to deal with several disappointments and bitter setbacks while trying to bring innovation in the dental Offering Best products to Transform Oral Healthcare Industry GC is known for gifting new concepts, technologies and 22 March 2019

  19. “Our team can deliver consistent quality across entire sales cycle from product to customer experience” Dr. Sriram Mudambi Managing Director platforms to the world. From the then “crystalline Cement” to glass ionomer restoratives materials all have the uniqueness of their own. Some of the widely acclaimed products of GC to Dental Industry are : ● Fuji II LC which is the India’s highest selling light-cured glass ionomer cement. ● All-round restorative with outstanding invisible aesthetics G aenial range. ● New Fibre reinforced materials EverX. ● New generation nano hybrid technology of Sculpt series ● Evolution in glass ionomer restorative is glass hybrid Ionomer Equia Going with the trend, GC has a specific focus on launching innovative products and establishing operational efficiencies to achieve customer delight. Patients value the pleasant environment, excellent service, and modern equipment just as highly as the expertise of their dentist. GC is providing a wide range of quality products; it makes the life of a dental practitioner quite easy. The company is a one-stop solution for a dental practitioner focused towards achieving excellence in clinical dentistry. The Journey towards Flourishing Future Dr. Sriram says “Looking ahead to our 100th anniversary in 2021, GC is making continued efforts under vision 2021 to become the number one dental company in the world through further contributing to a healthy, long-living society. We need to be proactive and make sustainable changes and innovations. Moreover, we need to increase our organizational strength and resilience to cope with change. There are several trends going on today but all of them have one clear link: minimally invasive dentistry. The ultra- conservative approach is gaining more relevance as technology provides us with better materials that allow minimum thickness while keeping the same physical properties with unrivalled aesthetics. GC is in the forefront with the digital product portfolio like Aadva IOS, Cerasmart, Proceed ceramic, Optiglaze & Lustre Paste and G-CEM LinkForce- the universal luting solution. Dr. Sriram firmly believes that these efforts are necessary for GC to flexibly cope with future changes in the external business environment, to become the world’s number one dental company and to enjoy prosperity in the coming years. Setting New Milestones in Healthcare Sector There are several trends going on today but all of them have one clear link: minimally invasive dentistry. The ultra- conservative approach is gaining more relevance as technology provides us with better materials that allow minimum thickness while keeping the same physical properties with unrivalled aesthetics. 23 March 2019

  20. How TECHNOLOGY Is Reshaping Medtech? T imes are changing and with each new innovation, several industries are undergoing fundamental changes. The health sector is one of the rapidly transforming industries of them all. In fact, if reports are to be believed, as the pace of change accelerates; medical technology companies can certainly expect a boost in the coming months and years! without opening organs in this manner they can perform more accurate operations. 2. Special Delivery There have been enormous steps made in pharmaceutical enterprises in a previous couple of years alone. The following period of pharma improvement will help expand productivity. With steady R&D activities leveled at the base, the not so distant future will see better methods concerning the transfer of therapeutic items. Research is as of now being led into making things where atoms can focus on the exact area of worry inside the human body. 3. New Infections But, what this change could bring can only be anticipated! It could be a hybrid of genetics and stem cells (biotechnology) with micro-bots (nanotechnology) and even cloud-based innovation! Whatever it may be, the medical technology market is currently viewed as a promising industry which not only will evolve with new trends but will also ensure a better quality of life. Let us go through the expected trends in MedTech that specialists should be prepared for: With the technological advancement, the risks of obscure sicknesses and chronic conditions also develop. New kinds of infection may show up because of the over the top utilization of virtual reality arrangements in gaming and different enterprises including medical technologies. Illustrations incorporate virtual post-traumatic stress disorder (v-PTSD) which may be a side effect for gamers who take part in expansive virtual fights wearing VR glasses, (for example, Call of Duty or Battlefield) and experience comparative indications as those soldiers who battled in genuine wars. Virtual reality as an augmentation of online movement and especially that of gaming may likewise cause serious addiction. 4. Real-time Diagnostics The wise careful blade was produced by Zoltan Takats of 1. Augmented Reality (AR) The computerized contact lens powered by Google plans to change the course of diabetes administration by estimating blood glucose levels from the patients’ tears. While the model is experiencing enthusiastic testing, controls must get ready to rapidly enable this disruptive innovation to enter the market and advantage patients. Microsoft Hololens can likewise change therapeutic instruction and how we look at the world by anticipating computerized data onto what we are seeing. A facility in Germany began trying different things with an application utilizing augmented reality on iPads in the OR. Amid activities, specialists can see through anatomical structures, for example, veins in the liver 24 March 2019

  21. Tech-Facts Imperial College London and works by utilizing an old innovation where an electrical current warms tissue to make entry points with insignificant blood damage. With the blade, the vaporized smoke is examined by a mass spectrometer to distinguish the synthetic substances in the biological example. This implies it can recognize whether the tissue is threatening or not. Specialists will love this careful Jedi blade which can essentially diminish the time duration of operations. Vipul Jain CEO 5. New Sight Numerous endeavors have been made to re-establish eyesight in individuals with harmed retinas, utilizing light-sensitive chips embedded into the back of the eye, or exceptional glasses which transmit electrical driving forces direct to the visual cortex of the mind. In any case, as option, researchers are currently reestablishing sight in individuals with macular degeneration, by planting stem cells in their retinas, which naturally separates to become one specialized retinal cell and connect with the optic nerve to provide vision. About The Author Vipul Jain is the CEO at Mirage Group, Advancells. He is a serial entrepreneur who specializes in spotting business opportunities while they are still in nuance stage. He did his MBA from Rochester Institute of Technology, Rochester, New York, Vipul started his career by establishing a fabrics import business as an extension of the family business of Garment exports in 1999. In 2013, Vipul established Advancells, which is a research based company focusing on providing cutting edge Stem Cell Therapies for patients with life threatening diseases also catering to lifestyle diseases and anti-aging technology. 25 March 2019

  22. THE10 MOST ADVANCED MEDICAL DEVICE COMPANIES Jainitri Innovations: T intrapartum-related neonatal deaths, and around 42% of the 535,900 maternal death occur worldwide. In India 80% of the deliveries are not done by doctors but nurses. During the intra-partum period, monitoring the foetal heart rate and uterine contractions is very important to know the health status of the foetus. Developing Sustainable Technology For Saving Lives At Birth another product called DAKSH which is an intelligent intra-partum monitoring mobile application. The gynecologist/expert doctor can view the data remotely on their mobile application and can also connect with the maternity ward in real time. he state of maternal and child care in low and middle income countries is very bad. Every year about 1.02 million intrapartum stillbirths, 904 000 About the Visionary Biochemical Engineer Arun Agarwal the Founder and CEO of Jainitri Innovations Pvt. Ltd was born and brought up in a small town in India.All throughout his childhood he witnessed his neighbours and family members falling prey to many fatal diseases. While pursuing his undergraduate course he realised that it was only technology that could save them all from these deadly diseases. With this motive to innovate new heath care machines he took up biochemical engineering for his post graduation. After completing his PG he roamed around in a lot of Indian villages to explore the various health issues. Out of all, maternal and child health problems seemed to be very huge, to tackle all these he came up with the idea of JANITRI. Jainitri Innovations has a vision to see a world where no mother or newborn die during pregnancy/delivery/post- delivery. For achieving this they cater some innovative simple and easy to use products that prevent the mortality/morbidity. KEYAR, an affordable version of CTG A device is used to continuously monitor the FHR & uterine contraction, it is called cardiotocography machine (CTG). Doctors analyse the CTG graph that comes on print to recognize the fetal distress. Based on the graph, the doctor takes further decisions to prevent any mortality or morbidity. There are a few challenges that we face with the CTG machine. Firstly, the cost of the machine is too high(2,00,000 INR), secondly, it is non-portable (4 KG), and lastly it requires a skilled health worker to operate the device and to interpret the graphs formed by the machine. To deal with the above mentioned issues, Jainitri Innovations has come up with a new product named KEYAR. Need for Improved Technology in Health Care Sphere To keep everyone healthy, there is a need to establish good healthcare centres that use high tech machines to detect various diseases. These machines in the health care industry require being non-invasive, portable, and easy to use for better monitoring or diagnosis. Home based healthcare monitoring and services are a good option and customers have started adopting the new technology. The artificial intelligence and machine learning has given a new shape to the health industry for early prediction. Technology is going to play the major role in this industry. This technology brought by Janitri Innovations is only going to help the healthcare workers but it can’t replace them. KEYAR is a reasonably priced and easy to use version of the CTG machine. It is a wearable and portable labor monitoring device for continuous monitoring of fetal heart rate and uterine contraction during intra-partum period for low resources healthcare settings. The easy format of this machiche enables a low skilled health worker to interpret the results. The KEYAR continuously transmits the data to Taking a Step Ahead Janitri Innovations Pvt. Ltd follows the process of “do 28 March 2019

  23. “More than 80% of the maternal and newborn mortality/morbidity can be prevented by providing the right innovation at the right place on right time” Arun Agarwal CEO and Founder early, fail early” and they innovate on a daily basis and then try and test the product or feature in the hospital (urban and rural) in real time to get the feedback of the relevant stake holders (nurses, doctors, patient). Based on the feedback, they take quick decision on modification or inclusion or removal of any technology component. They also keep an eye on their competitors across the globe and the market requirement. If you wish to make a change, a good team is always the first requirement. Getting the right people in their team is the biggest challenge this company faces. Right now at Janitri they have a highly skilled and talented team of candidates who are passionate about their expert area and social sector. This helps the overall team to grow together with the vision of the company. Subsequently, the client gets the benefit from their product and services that are designed and developed by the zealous and enthused team. Team - The Major Asset of the Company The main success of the company will be when their product saves many lives and decreases the death rate. This company has come a long way starting from problem identification, need validation, product development and pilot. Their partners VILLGRO, BIRAC, Government of Karnataka, Government of Rajasthan, Gates Foundation, WISH Foundation, SELCO Foundation, Karuna Trust, Grand Challenges Canada, St. Johns medical college hospital and Rangadore memorial hospital have helped them through it all. Maintaining long term relations with clients is their main agenda. They make sure to provide the quality product, on ground training, refresher training and quality maintenance to whosoever wishes to work with them. 29 March 2019

  24. CLEANING & DISINFECTING DISINFECTING Services of he process of cleaning and disinfecting the medical devices can be carried out by decontamination. This process is used so that these devices can be reused or can be tested by the engineers. The recently used devices must be decontaminated before they can be handled by anyone in order to ensure the safety of the staff. To complete such tasks, firms must have the necessary certification for the decontamination process and must follow the guidelines to reduce the risks alongside the exposure of bio-hazardous materials like blood, body, and tissue to the workers. If the corporation cannot conduct these tasks themselves then they must outsource this activity to the third-party vendors. The main three levels of decontamination are cleaning, disinfecting, and sterilization. Medical Devices T Sterilization The application of high levels of heat to kill the highest level of microorganism along with getting rid of transmissible agents is called sterilization. In this, transmissible agents like spores and bacteria are eradicated. Sterilization methods mostly depend on the device’s ability to withstand the heat and extent of sterilization requirement. For example, devices with tubular openings require low steam level and other devices require high steam level. Some of the common sterilization methods are; Ethylene Oxide (ETO) It is one of the most popular methods of sterilization. It involves the exposure of medical devices with ethylene oxide gas. This gas is an alkaline agent, infiltrate the packed medical device and kills microorganisms, thus achieving sterilization. The process of ETO is toxic and flammable at low temperature and is used on products that cannot withstand the high-temperature process. This process is applied to • Plastic packaging disclosed with irradiation • Devices with electronic components • Materials that get damage at high temperatures • Custom kits • Materials not compatible with gamma or steam sterilization. Cleaning It is the first and most important step in the decontamination process. It involves the removal of both visible and non-visible substances from the medical device with water and detergent. Decontamination This is the next step in the process and is used to kill the non-spore forming bacteria on medical devices. Some of the most commonly used disinfectants in the decontamination process are; • Sodium Hypochlorite • Liquinox • Cidex (Glutaraldehyde) • Isopropyl Alcohol Alconox • Ethyl Alcohol Irradiation Methods (Gamma and E-beam) These irradiation methods, gamma, and e-beam are radiation based sterilization techniques. The gamma one deals with the exposure of the product with high gamma rays continuously and the latter one uses the electron 30 March 2019

  25. Editor’s Choice beams. Both these methods are effective; however, e-beam is more powerful than the gamma radiation. Reusable devices undergo audit after these radiation methods in order to ensure that they meet established standards and sterilization methods. Steam Sterilization This is the simplest, yet effective decontamination method. Sterilization is attained by exposing the devices in the saturated steam at high temperatures. The devices are placed in another device called autoclave and are heated through pressurized steam to eliminate the microorganisms including spores. Consequently, this method is not appropriate for many materials that cannot withstand high temperatures. Another point to be noted here is that there is a down time required, once the products are sterilized. The devices must be dry before being removed from the autoclave. Once removed, they must be must be allowed to cool down to ambient temperature, which can take several hours. Dry Heat Sterilization One of the easiest ways of sterilization is by using the dry heat method. As the name suggests, it uses hot air that is free from water and vapor, and where moisture plays no role in the process. The process is accomplished by conduction i.e. heat is absorbed by the external surface and is passed inward to the next layer. Eventually, the entire device reaches a certain temperature that is required to achieve sterilization. A major thing to note down here is that the instruments should be dry beforehand because water can interfere with the overall process. Packaging and Transportation Guidelines There are critical guidelines that need to be followed in packaging and transporting contaminated medical devices because of the involved bio-hazardous risk. Transport and Logistics companies insist on packaging and transporting diagnostic specimen and test samples, which must include the four basic components: • Absorbent material • Watertight primary receptacles • Sturdy outer packaging • Watertight secondary receptacles Sterility Assurance Level (SAL) The process of SAL can be defined as the probability of a single device being non-sterile after being subjected to the sterilization process. Once the device has been sterilized, tests can be conducted to determine if the desired level of sterility is attained or not. If these medical devices are not decontaminated and cleaned between the users, these devices may transmit infectious agents between the units, patients, and can be brought with the patients from healthcare institutions. Hence, the increase in the hygienic quality of these devices to standard levels is a must requirement in the modern medical practice. 31 March 2019

  26. THE10 MOST ADVANCED MEDICAL DEVICE COMPANIES Vinod Medical Systems Pvt. Ltd.: T equitable citizens. This in turn presents an enormous opportunity with the large population, growing economic prosperity and the disease burden. Industry players believe that a campaign like “Heal In India” will be synergetic to Make In India initiative. An attractive Heal In India campaign can result in a significant expansion and upgradation of healthcare infrastructure in the country, benefiting Indian residents and providing value addition through medical tourism. Vinod Medical Systems Pvt Ltd is focused to deliver the highest quality products and so the dedicated team has been trained to interact with clients positively to ensure their needs are addressed satisfactorily. Emphasizing on Customer Satisfaction through Quality Products he healthcare industry in India has made rapid progress in the last decade, but significantly lags behind other nations in availability and quality of The core team of Vinod Medical System comprises of Suresh Rathi - Managing Director, Vinod Jaisinghani - Director, Sales (Medical and Photo), Narayan Rathi - Director, Sales (Signage, Accounts and HR), Kailash Rathi - Director, Sales (Photo and Administration). It was Suresh Rathi’s dream to do manufacturing and this was fulfilled in 2009 when the Photo- sensitized confectioning plant was established in Dadra, Dadra and Nagar Haveli (U. T.) and later in 2011 when the Hospital Furniture factory commenced operations. Emerging from a trading company and growing into a manufacturing one, the company is now poised to enter the Global Market with a strong and firm endeavor. “The belief in achieving excellence through quality products empowering employees and practicing ethical business policies are the driving force for the expansion of the business to which I am committed and will uphold.” asserts Suresh Rathi. The organization keeps abreast of new and emerging technologies and products in the field and offers these to the customers so they are benefitted with the latest items in the market. It aims to expand the marketing of the organization globally with top quality Hospital Furniture and other consumable specialty products with the extension of the good business practice, valued customer relationship and empowered employment. The target is to grow exponentially in the forthcoming years on the basis of the planned strategies and to evolve into a Preferred Business Associate. Rise and Growth of the Organization VMS has grown from the trading business started in 1988 to a manufacturing company since 2009 with two Quality Certified production plants in India. Photo sensitized confectioning facility with ISO 9001:2015, ISO 14001:2015, ISO 13485:2016, CE and WHO-GMP certification for slitting and packing of products like Medical and Industrial X-ray films, Color papers and films, high quality coated inkjet papers and films. Hospital Furniture manufacturing unit certified for ISO 9001:2015, ISO 14001:2004, ISO 13485:2003, CE, OHSAS 18001:2007 and WHO-GMP. l The Efficient team of Vinod Medical Systems Suresh Rathi and Vinod Jaisinghani started the trading business in 1988 under the name Vinod Agencies for Graphic Art Materials. This business being associated with photography, it naturally led to the trading of Agfa Medical X-ray films and Kodak Photo products. Further with the change of name to Vinod Medical Systems Pvt. Ltd., and establishing branches all over India, the company diversified the business to deal in Medical, Healthcare, Photo related products and Signage products. l The registered office is in Raipur with the corporate office established in Mumbai. Network of 22 offices in India with more than 300 channel partners enables a deep and strong penetration of the marketing and sales force. 32 March 2019

  27. “The company believes in achieving excellence through quality products empowering employees and practicing ethical business policies” Suresh Rathi Managing Director The wide range of products include hardware and consumables for the Healthcare, Photographic and Signage industries procured from long standing and quality conscious domestic and international companies. The brand majorly deals with trends and products thereof. At the same time Vinod Medical System participates in exhibitions and seminars held in India and abroad to get the market feel. The International suppliers of the organization includes Agfa, Kodak, Fujifilm, Carestream, GE, Malvestio, Siemens and introducing their products in India along with their very own brand of VMS products are the ones well accepted by every customer that it has targeted. Medical / Healthcare - Medical X-ray Films, Skydent Dental X-ray Films, Industrial X-ray Films, X-ray Cassettes, Screens and Accessories, X-ray Process Chemicals, Ultrasound Gel, Ultrasound Thermal Printing Papers, X-ray Radiography Systems, DR Panels and a wide range of Hospital Furniture. Photo - High quality Inkjet Papers in various surfaces and thickness including Photo quality, Digital Print Media, Copier Paper, Colour Inkjet Cartridges, Toner Cartridges, Refill Inks, CISS Tanks, Lamination Films, Laminators and Epson Wide format Printers Signage – Vinyl media for Front lit, Back lit, Eco Solvent, Reflectives, Inks for vinyl printers and Large format printers, CNC Routers for wood and stone engraving, Plotters and Laminators Retail – Natural ice-cream parlors and confectionery items in the state of Chhattisgarh. l To build a long term relationship and have a successful customer base, the organization believes that only with trust between the customer and the company a successful business can be assembled. The team is motivated to build this rapport by offering customers what they need, when they need and at an affordable price coupled with a back-up of service and support. l l Progressing Forward with a Positive Outlook for the Future VMS has always been and will continue to be a business house offering the very best and latest technology products in each of the verticals. The organization is continuously looking for emerging trends and technologies and incorporating these into the manufacturing, marketing and sales. With the committed investment in Human Resources, Quality Products and Reliable Services, the company is looking forward to increasing its Value and Presence in the Domestic and International Business. l Upholding a Good Rapport with Suppliers Considering the steady decline in traditional Medical X-ray film use in healthcare, the company has adapted to offering DR systems as a substitute. Also to keep pace with the growing demand in quality healthcare products, new technologies have been incorporated in the manufacturing to enhance productivity and quality. The organization maintains a good rapport with all the international and domestic suppliers who constantly update them with new 33 March 2019

  28. Dr. V. Mohan Chairman & Chief Diabetologist 36 March 2019

  29. MedTech Spotlight Latest Technologies in Diabetes here have been tremendous advances in technology used for the management of diabetes over the past few years. Technologies most commonly reported are in the arena of needles and injections used in insulin delivery and devices that can manage blood glucose and prevent long-term complications. T Moreover as they are insulated, it is not necessary to keep the pen in a refrigerator. This makes life much easier especially for busy people who travel a lot. However, Insulin pens are more costly than insulin vials. Advances in Insulin Delivery Devices from the beta-cells of the pancreas. The insulin pump represents an attempt to provide insulin in a more physiological manner to patients with diabetes, avoiding the peaks and troughs in insulin levels seen with multiple subcutaneous injections. a) Insulin pumps The insulin pump consists of a subcutaneous cannula inserted into the interstitial space (usually of the anterior abdominal wall), a connecting tubing and a small pager sized, battery operated pump which has the insulin reservoir as well as a microchip that controls insulin delivery according to pre-programmed rates. Insulin Pens Have Become Better, More Accurate and Less Painful Conventionally, insulin used to be given in syringes and a vial of insulin. In earlier days the needles were long and painful and the vial has to be kept in a refrigerator. All this changed when insulin pens were introduced. Insulin pens are more useful as they eliminate the need for drawing up a dose in a syringe. The ability to dial up the desired dose leads to greater accuracy and reliability, especially for low doses which are often needed in the elderly and in small children. The sensory and auditory feedback linked with the dial mechanism on many pens, also helps patients with visual impairment. Pen devices are also more compact, portable and easier to grip. b) Artificial Pancreas These are modern insulin pumps with built in glucose sensors. The ultimate Artificial Pancreas (under development now) would be able to automatically deliver the correct doses based on the blood sugars and switch off the delivery if the sugars are low! All patients with type 1 diabetes and many with type 2 diabetes require insulin therapy to control their blood glucose levels. Notwithstanding the tremendous advances made in insulin therapeutics over the past three decades, glycemic control remains suboptimal in the majority of patients on insulin. A major reason for this paradox is that the currently used insulin regimens do not exactly mimic the physiological secretion of insulin Use of Technology in Monitoring Glucose Levels a) Blood glucose meters Blood glucose meters have been used 37 March 2019

  30. in clinical practice since the 1970’s. However their widespread use started only in the 1990s after technological improvements led to a reduction in the cost of the meters and reagent strips. The latest glucose meters provide results that are comparable in accuracy to the venous plasma glucose estimations, at comparable or even lower costs. downloaded in the form of graphs using a proprietary software .The graphs provide glucose curves for each of the 14 days, as well as a “modal day” curve prepared by collapsing the readings from 14 days into a single curve. and other healthcare facilities. It has been used to overcome distance barriers and to improve access to medical services that would often not be consistently available in distant rural communities. Electronic Medical Record (EMR) can transform the way healthcare is delivered. EMR is a patient centered record, which contains medical, and treatment history of the patient and this information can be made available online whenever it is needed to authorized users. The AGP is an improvement upon the original continuous glucose monitoring system in its longer duration of recording and in that, there is no need of calibrating with a capillary glucose meter. It is also far less expensive. The FGM is a useful educational and motivational tool for patients in addition to helping the clinician plan and titrate anti diabetic drug regimens more accurately. The advent of glucose meters and strips has made self-monitoring of blood glucose an integral part of diabetes care particularly in patients who are on insulin. Precision Diabetes: Now in India At Dr. Mohan’s Diabetes Specialities Centre, over the last several years we have developed algorithms by which a precise diagnosis of diabetes can be made. Applying the principles of ‘Precision Diabetes’, it will be possible in the near future to very accurately classify a patient and determine the type of diabetes he or she has, and then decide the type of treatment that this patient is likely to respond to. These are indeed exciting times in the field of diabetology. b) Continuous Glucose Monitoring (CGM) Today we have devices which can continuously monitor the glucose levels using sensors applied to the body. These are particularly useful for those who have fluctuating glucose levels. Use of Mobile Phones (mHealth/mDiabetes) Today it’s a mobile world. Smart phones are everywhere, giving more people instant access to information at their fingertips. This trend has led to growing popularity and use of mobile health technology. Mobile health technology is making health care more accessible and more flexible, places more power in the hands of patients, and is contributing to greater efficiency at medical practices. Various apps are now available to measure your diet, exercise and track your body weight glucose levels, blood pressure, cholesterol etc. You can also communicate the results to your doctor or health care provider making remote monitoring possible. c) Ambulatory Glucose Profile (AGP) Conclusions This review sums up some of the technologies in practice for the management of diabetes. It ought to be remembered that any device or technology, is only as good as the person who uses it. The success of these technological advances will rely significantly on the willingness of patients and doctors to adopt them and to utilize them to the fullest. The Ambulatory Glucose Profile device consists of a small sensor which is worn continuously by the patient for the duration of the profiling (up to 14 days). The glucose values recorded by the sensor are wirelessly transmitted to a reader (usually kept with the healthcare provider) and Use of Telemedicine Telemedicine has now transformed into a complex integrated service used in hospitals, private physician offices, 38 March 2019

  31. Biography Dr. V. Mohan is the Chairman and Chief of Diabetology at Dr. Mohan’s Diabetes Specialities Centre at Chennai in South India which is a WHO Collaborating Centre for Non-communicable Diseases Prevention and Control and IDF Centre of Excellence in Diabetes Care. He is also President and Director of the Madras Diabetes Research Foundation which is an ICMR Centre for Advanced Research on Diabetes. Deeply interested in research from his undergraduate medical student days, Dr. Mohan has published over 1200 papers in peer reviewed journals including 750 original articles, 250 review articlesand invited editorials and 150 chapters to textbooks on Diabetes and Internal Medicine which is a world record by practicing doctor. His work has received over 59,000 citations and has a h index of 110 which is the highest by a medical doctor in India. Dr. Mohan has trained over 12,000 physicians & 500 diabetologists in addition to Nurses, Educators and Technicians. Dr. Mohan has received over 170 awards including the prestigious Dr. B.C. Roy National Award by the Medical Council of India and the Dr. B. R. Ambedkar Centenary Award from the Indian Council of Medical Research, the highest award for Biomedical research in India. In 2018 he was conferred the prestigious Dr. Harold Rifkin Distinguished International Service in the Cause of Diabetes Award by the American Diabetes Association for his pioneering work in the field of diabetes and he is the first Indian to receive this award. For his extensive contribution in the field of diabetes, in 2012 Dr. Mohan was awarded the prestigious Padma Shri,one of the highest civilian awards given by the Govt. of India. Dr. Mohan also provides lifelong free treatment to thousands of poor patients through the free diabetic clinics established by him and has conducted over 3000 free diabetes camps including several along with the Sri Sathya Sai Seva Organizations and Trusts. 39 March 2019

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