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Non-Sporeforming Anaerobes

Non-Sporeforming Anaerobes. Non-Sporeforming Anaerobes. Stains gram-variable or gram-negative, but not a gram-negative cell wall. Non-Sporeforming Anaerobes (cont.). Most Common Sites of Anaerobic Infection. Characteristics of Anaerobic Infection.

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Non-Sporeforming Anaerobes

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  1. Non-Sporeforming Anaerobes

  2. Non-Sporeforming Anaerobes Stains gram-variable or gram-negative, but not a gram-negative cell wall

  3. Non-Sporeforming Anaerobes(cont.)

  4. Most Common Sites of Anaerobic Infection

  5. Characteristics of Anaerobic Infection

  6. Characteristic Clinical Signs of Anaerobic Infection

  7. Anaerobic Gram-Positive Non-Sporeforming Bacterial Infections

  8. Gram-Positive Non-sporeforming Anaerobes NOTE:Figure legend in text indicates that each of these organisms is a bacillus (i.e., rod-shaped). This is INCORRECT. Peptostreptococcus is, as the name indicates, a coccus.

  9. Diseases Associated with Anaerobic Gram-Positive Bacilli

  10. Gram Stain and Macroscopic Colonies of Actinomyces NOTE:Molar tooth appearance of colonies on agar can help remind us that the oral cavity is a common niche for Actinomyces.

  11. Actinomyces Infections

  12. Cervicofacial Actinomycosis NOTE:Sinus tract originating in oral cavity has made it’s way to the surface at the jawline.

  13. Colonized IUD Resulting in Pelvic Actinomycosis

  14. Epidemiology of Actinomycosis

  15. Sulfur Granule from Sinus Tract of Actinomycotic Infection

  16. Epidemiology of Propionibacterium (doxycycline)

  17. Anaerobic Gram-Negative Non-SporeformingBacterial Infections

  18. Anaerobic Gram-Negative Infections

  19. Anaerobic Gram-Negative Infections (cont.)

  20. Clinically Predominant Anaerobic Gram-Negatives

  21. Broad Classes of Virulence Factors Associated with Gram-Neg. Anaerobes • Adhesins • Protection from: • Oxygen toxicity • Phagocytosis • Tissue Destruction

  22. Anaerobic Gram-Neg. Virulence Factors

  23. Anaerobic Gram-Negative Virulence Factors (cont.)

  24. Epidemiology of Bacteroides

  25. Bacteroides Gram Stain

  26. Bacteroides Virulence Factors

  27. MIXED [1] [5] [3] [4] [2] [6] [8] [7] MIXED + MIXED + LIVE LIVE DEAD SUBUNIT SUBUNIT Bacteroides Pathogenicity

  28. REVIEW Non-Sporeforming Anaerobes

  29. Characteristics of Anaerobic Infection REVIEW

  30. Characteristic Clinical Signs of Anaerobic Infection REVIEW

  31. Most Common Sites of Anaerobic Infection REVIEW

  32. Review of Anaerobic Gram-Positive Non-Sporeforming Bacterial Infections REVIEW

  33. Gram-Positive Non-sporeforming Anaerobes REVIEW

  34. Actinomyces Infections REVIEW

  35. Epidemiology of Actinomycosis REVIEW

  36. Epidemiology of Propionibacterium (doxycycline) REVIEW

  37. Review of Anaerobic Gram-Negative Non-SporeformingBacterial Infections REVIEW

  38. Anaerobic Gram-Negative Infections REVIEW

  39. Anaerobic Gram-Negative Infections (cont.) REVIEW

  40. Clinically Predominant Anaerobic Gram-Negatives REVIEW

  41. Broad Classes of Virulence Factors Associated with Gram-Neg. Anaerobes • Adhesins • Protection from: • Oxygen toxicity • Phagocytosis • Tissue Destruction REVIEW

  42. Anaerobic Gram-Neg. Virulence Factors REVIEW

  43. Anaerobic Gram-Negative Virulence Factors (cont.) REVIEW

  44. Epidemiology of Bacteroides REVIEW

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