Platelet Rich Plasma Gel

5. Platelet Rich Plasma –PRP is obtained by sequestering and concentrating platelets by gradient density centrifugation Platelet Rich Plasma Gel

6. Platelet rich plasma gel is an autologous modification of fibrin glue made by mixing platelets and fibrinogen centrifuged from whole blood with thrombin and calcium chloride. Increase platelet concentration in wound by more than 300 percent.

10. Platelet enriched plasma Autologous thrombin

11. Platelet Rich Plasma plus Bio-Oss plus Biogide versus Platelet Rich Plasma and Bio-Oss Comparison of Platelet Rich Plasma, Bovine Porous Bone Mineral and Guided Tissue Regeneration versus Platelet Rich Plasma and Bovine Porous Bone Mineral in the treatment of Intrabony defects: a Re-entry Study Lekovic V, Camargo PM, Weinlaender M, Vasilic N, Kenney EB J. Periodontol 2002, 73:198 21 Paired Defects 6 Males, 15 Females 9 smokers 12 non-smokers Mean age 40 years 6 month clinical and re-entry data

17. Platelet Rich Plasma plus Bio-Oss plus Atrisorb versus Atrisorb alone Platelet Rich Plasma and Bovine Porous Mineral combined with guided tissue regeneration in the treatment of intrabony defects in humans. Camargo PM, Lekovic V, Weinlaender M, Vasilic N, Madzarevic M, Kenney EB J Periodont. Res 2002, 37:300 18 paired defects 10 males 8 females 6 smokers 12 non-smokers Mean age 39 years 6 month clinical and re-entry data

19. Bio-Oss plus Bio-Gide plus Platelet Rich Plasma versus Flap Debridement A Re-entry study on use of Bovine Porous bone mineral guided tissue regeneration and Platelet Rich Plasma in the treatment of intrabony defects in humans. Camargo PM, Lekovic V, Weinlaender M, Vasilic N, Madzarevic M, Kenney EB Int. J. Periodont. Rest. Dent. 2005, 25:49 28 Paired Defects 12 Females 16 Males Mean age 41.0 years 12 Smokers 16 Non-smokers Clinical and re-entry data at 6 months

26. Platelet Rich Plasma Comparison between Bio-Oss/Bio-Gide/PRP and Bio-Oss/Bio-Gide Preparing for publication 23 patients Interproximal defects Mean age 38 9 smokers, 14 non-smokers Re-entry 6 months

29. Recombinant Human Platelet Derived Graft Factor with DFDBA Periodontal Regeneration in Human Class II Furcations using Purified Recombinant Human Platelet Derived Growth Factor – BB (rhPDGF-BB) with Bone Allograft Camelo M et al Int J Periodont Rest Dent 2003, 23:213 3 mandibular molars, 1 maxillary 2 got 0.5mg/ml PDGF+DFDBA 2 got 1.0mg/ml PDGF+DFDBA 9-month results Block sections

52. Genetically engineered human Bone Morphogenetic Proteins increase the amount and purity . Osteogenin is another name for B.M. P. Most osteogenins are bound to a carrier of bovine type I collagen sponge or other carrier.

60. Got good bone in cores One patient had mucus retention cyst on CT at 16 weeks Got mean bone height increase of 8.51 mm to 15.73 mm 8 to 11 patients had sufficient bone for implant placement. 2 biopsies at 19 weeks had moderate amount of bone 10 biopsies at 24 to 27 weeks had moderate to large amounts of bone.

61. This Bovine protein extract (Neo osteo, Sulzer) contained Bone Morphogenetic Proteins 2, 3, 4, 6, 7, 12, 13.