1 / 54

Biodistribution of Radiopharmaceuticals

Biodistribution of Radiopharmaceuticals. Properties of a Radioactive Element That Determine Tissue Localization and Excretion.Determinants of Localization of Radioactive DrugsDeterminants of Renal Excretion. Properties of a Radioactive Element That Determine Tissue Localization and Excretion. Oxid

Mia_John
Download Presentation

Biodistribution of Radiopharmaceuticals

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

    1. Biodistribution of Radiopharmaceuticals Jim Corley, RPh, MS, BCNP Medical College of Georgia

    2. Biodistribution of Radiopharmaceuticals Properties of a Radioactive Element That Determine Tissue Localization and Excretion. Determinants of Localization of Radioactive Drugs Determinants of Renal Excretion

    3. Properties of a Radioactive Element That Determine Tissue Localization and Excretion

    4. Oxidation state at physiologic pH Solubility of the stable state Tendency toward incorporation into organic compounds Tendency to be chelated or to form protein complexes in circulation or in a particular tissue Chief Determinants of Biological Localization

    5. Oxidation State, Ionic Size and Charge

More Related