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Utility of FEM and FEA. Evaluate possible designs without manufacturing a prototype Augment experimental capabilities time money. Heart Disease. 4 million patients in the U.S. are victims of heart failure, and nearly 400,000 new cases are diagnosed each year 2,800 receive heart transplants
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Utility of FEM and FEA • Evaluate possible designs without manufacturing a prototype • Augment experimental capabilities • time • money
Heart Disease • 4 million patients in the U.S. are victims of heart failure, and nearly 400,000 new cases are diagnosed each year • 2,800 receive heart transplants • Heart disease is the leading cause of death and disability in the U.S.
Arrow LionHeartTM • LVAD (Left Ventricular Assist Device) • electric pulsatile blood pump • fully implanted in upper abdomen • 70 cc volume 8 L/min at beat rate of 135 = stroke volume of 60 cc
Introduction Poly(urethaneurea) Blood Sac Pusher- plate Titanium Pump Case
Introduction • Design goal: 2 yrs @50,000,000 cycles/yr = 100,000,000 cycles • FEA used to evaluate various pump designs and their effectiveness at reducing the material stresses
Finite Element Model • Axisymmetric • Pusherplate and pump case treated as rigid • 8-node continuum elements • Blood sac : homogeneous, hyperelastic (non-linear) • Frictionless contact
0.9 in 2.86 in Finite Element Model
Boundary Conditions • Internal pressure = 100 mm Hg • Rigid pump case was fixed in space • Pusherplate displaced 0.8 inches • 30 increments • simulating ejection stroke of pump
Parametric Study • 3 different thickness sacs (0.015, 0.02, 0.025 inches) • 2 pump case designs (tapered, not tapered) • 2 radii of curvature for sac (3/16 and 7/16 inch) • Total of 12 cases
3/16 inch of stroke 3/8 inch of stroke end of stroke
2 3 4 1
Conclusions • Material stresses and strains are sensitive to the thickness of the blood sac • Radius of curvature has little influence on the peak stress in the blood sac, however, it does affect when the peak stress occurs during the stroke cycle
Conclusions • Tapering the pump case can significantly alter blood sac stresses • All stresses and strains were much lower than the yield stress and strain for poly (urethaneurea)
News Release (Feb. 28th, 2001) • First fully implantable heart assist device implanted • As of March 12th, Arrow LionHeartTM recipient is stable and recovering as expected
Total Artificial Heart • Fit into chest cavity • 50 cc • Develop a model to predict and minimize stresses in biomaterials, so that the durability of a reduced-size device is not adversely affected by pump scaling