Metastatic Cancer

1. HOW TO KNOW IF YOU HAVE ADVANCED MALIGNANT PECOMA Perivascular epithelioid cell tumors (otherwise known as PEComas) are one of a variety of mesenchymal tumors that are rare and are primarily made up of immune histochemically and histologically distinct perivascular epithelioid cells. This is the causal agent of advanced malignant pecoma and can originate intuitively in any soft tissue or organ such as pancreas, kidney, liver, uterus, bone, heart, breast, vulva, bile duct, base of the skull, lungs, breasts, the skin as well as the soft tissue of the abdominal wall and thighs. A variety of lesions like clear cell ‘sugar’ tumor of the lung, angiomyolipoma, etc. also accompanies the growth of the epithelioid cells. Few symptoms are associated with advanced malignant PEComas and the commonly noticeable symptoms in almost all cases of this type of cancer are mostly bleeding and abdominal pain. The rare nature of Perivascular epithelioid cell tumors makes it difficult to clinically and biologically study their behavior.

2. PEComas are tumors that are distinguished by a melanocytic difference. Extremely few cases of PEComas have been reported in the colon; roughly less than o.1 percent of colon cancers have been described. Due to this low rate of recurrence and also because the features which determine the microscopic tissue study of PEComas, it is essential to carry out a differential diagnosis to eliminate the existence or presence of other types of tumors. A preoperative diagnosis such as melanoma, gastrointestinal stromal tumors, clear cell sarcoma and leiomyosarcoma are included. A precise preoperative analysis is hard to carry out because of lack of specific radiological elements. A preoperative biopsy might have been in place to surmount this shortcoming, but it has long been discovered through clinical data and practices that the diagnosis of PEComas is mostly confirmed after a surgical operation. The biological-behavioral pattern of PEComas in different cases was heterogeneous; some of the cases developed recurrence, metastasis and eventually led to the death of the patients. There is no final treatment of advanced malignant PEComa. The major method of treatment of advanced malignant PEComas is via surgical expurgation or resection for cases that are non-threatening. Because of the poor prognosis which usually accompanies metastatic or infiltrative tumors, other options of treatment such as radiotherapy, immunotherapy as well as chemotherapy has been employed in locally advanced, malignant and metastatic histology tumors. Controversies still ensue due to the low occurrence of PEComas, particularly in complex cases. The best way to combat advanced malignant PEComa is to identify it as early as possible, for this will aid medical personnel in helping the patient to manage the case appropriately. Due to its unpredictable nature, you will do well to visit mypecomastudy.com, a clinical research study center that will assist in shortening or delaying the growth of malignant PEComas in your body.