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What is DLCO?. The diffusing capacity of the lung for carbon monoxide (DLCO), also referred to as the transfer factor of the lung for carbon monoxide (TLCO)It is used to evaluate the transfer of gas from the distal air spaces into the pulmonary capillaries. 2. What is DLCO. It is measured when a known but very low concentrations of carbon monoxide (CO) is inspired. The rate of CO disappearance is calculated from the ratio of the CO concentrations of the inspired and expired gas and then expre9462
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