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ALS/PDC of Guam. The Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Complex (ALS/PDC) in the Chamorro Indians of Guam has been a focus of intense research interest for over half a century Known by the Chamorro people as lytico-bodig, the disease was described by American researchers visiting Guam after World War II to occur at a rate more than 100 times that of ALS in the continental United States (Arnold et al. 1953 )ALS/PDC may present as a motor neuron syndrome similar to ALS, or a pro9454
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