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Fasciola hepatica

Fasciola hepatica. Jeremy Leibfried Tyler Gronli. Introduction. Phylum: Platyhelminthes Flat worm Liver fluke Effects sheep, cattle, and sometimes humans. Interesting Facts. Eggs found in mummies 1 st fluke or trematode to be reported 1379 Reported in Publication ( Le Bon Berger )

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Fasciola hepatica

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  1. Fasciola hepatica Jeremy Leibfried Tyler Gronli

  2. Introduction • Phylum: Platyhelminthes • Flat worm • Liver fluke • Effects sheep, cattle, and sometimes humans

  3. Interesting Facts • Eggs found in mummies • 1st fluke or trematode to be reported • 1379 Reported in Publication (Le Bon Berger) • 1st discovered in sheep

  4. F. hepatica • Definitive host: • Sheep • Cattle • Humans (Accidental) • Other Mammals • Intermediate host • Fresh Water Snail • Geographic Range • Cosmopolitan; anywhere sheep and cattle are raised

  5. Morphology • Adult fluke • Flat leaf like body • 20-30mm long • 8-15mm wide

  6. Site of Infection • Ingestion Metacercariae • Ex-cyst in Duodenum • Burrows through Intestinal Wall • Enters Peritoneal Cavity • Migrates to Liver

  7. Miracidia Egg Cercariae Metacercariae

  8. Symptoms • Abdominal Pain • Anemia • Hepatic Tenderness • Hepatomegaly resulting from Edema • Intermittent Fever • Jaundice • Lethargy • Nausea • Prolonged High Fever • Secondary Infections • Vomitting

  9. Symptoms • Acute • More common in sheep • 10,000+ Metacercariea consumed at one time • Dramatic Liver Inflamation, Frequently Resulting in Death • Chronic • More Common and Rarely Fatal • Nonspecific Symptoms • Halzoun • Eating raw, infected liver • Infects pharynx • Causes swelling and obstructs breathing

  10. Diagnosis • Stool Samples • Yellow-Brown Eggs • Eggs Don’t Show for 4 Months • Duodenal or Biliary Aspirate • Antibody Test • Can detect 2 Weeks After Infection • Ultrasound • Visualize Adults in Bile Duct • CT Scan • Reveals Burrows in Liver

  11. Treatment • Bithional • Highly Effective • Large Dose • High Cost • Long Treatment Period • Triclabendazole • Easier to Use • 1-2 Oral Doses in 24 hrs • Virtually 100% Effective • Surgery

  12. Control Methods • Eduaction • Cheapest and Most Cost Effective Way • Wash Aquatic Vegetables in 6% Vinegar for 5-10 minutes • Better herding practices • Keep herds away from aquatic areas • Moluskicide • Controls Intermediate Snail Host

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