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BASICS OF HIV. D.Vijay kumar Dist.sales Manager, Abbott Hyderabad. INTRODUCTION. Family: Retroviridae Sub family: Lentivirinae Genus: Lentivirus Types: HIV-1 HIV-2. The HIV virus is responsible for spread of pandemic disease “ AIDS ”
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BASICS OF HIV D.Vijay kumar Dist.sales Manager, Abbott Hyderabad
INTRODUCTION • Family: Retroviridae • Sub family: Lentivirinae • Genus: Lentivirus Types: HIV-1 HIV-2
The HIV virus is responsible for spread of pandemic disease “AIDS” • HIV is a great challenge to public health in modern times. • The infection is truly global in its magnitude & is unlikely to spare ay continent, nation, race or political system.
HISTORY • Summer season – 1981 • Newyork and California • Sudden increase in incidence of 2 very rare diseases 1.Kaposi’s sarcoma2.Pneumocystis carinii pneumonia in young homo sexuals and drug addicts. • Collapse of immune system and death due to opportunistic infections.
LUC MONTAGNIER & HIS COLLEAGUES: 1983 – Pasteur Institute of Paris – Isolated a virus from a African patient suffering from PGL – “LAV”
ROBERT GALLO & HIS COLLEAGUES: 1984 – National Institute of Health, USA – isolated a virus from an AIDS patient – HTLV –III
ARV – AIDS Related Virus: common name given for the viruses discovered so far. Antigenically different but common origin.
INTERNATIONAL COMMITTEE ON VIRUSNOMENCLATURE: 1986 – To avoid confusion a generic name “HIV” was coined
Dr. SUNITY SOLMON: 1986 – Detected the first case of AIDS in Chennai.
WORLD AIDS DAY: 1988 – The first worlds AIDS day was celiberated on 1st December. • RED RIBBON: Becomes an international symbol of AIDS awareness in 1991.
SOME INTERESTING FACTS • Originated from monkeys and chimpanzees in Africa • CAMAROON in West Africa – mostly affected area • In India AP is one of the 6 “hard hit” states – Maharashtra, Tamilnadu, Karnataka, Manipur & Nagaland
In AP – East Godavari, Guntur, Warangal, Vishakhapatnam, Chittoor, Karnul • STD suffering patients are more prone to HIV infection • Males / Females ratio is 3:1 • 90% of total reported HIV cases are between 15-44 years
Urban/Rural incidence: 20% Urban 30% Rural • Business class people are more prone, then unemployed, drivers, agriculturists and house wives. • TV – most likely source of HIV/AIDS knowledge, followed by friends or relatives.
Mode of transmission: • 75% by hetero sexual contacts • 8% by Blood transfusion • 7% by injectable drug use • 2.4% by mother to child