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State of Clinical HIV Research in Africa

State of Clinical HIV Research in Africa. Elly T Katabira, FRCP Department of Medicine Makerere University Medical School Industry and HIV Clinical Research – Focusing on women and children Dakar, Senegal, December 3, 2008. Some of the research being done in Africa. HIV prevention studies

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State of Clinical HIV Research in Africa

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  1. State of Clinical HIV Research in Africa Elly T Katabira, FRCP Department of Medicine Makerere University Medical School Industry and HIV Clinical Research – Focusing on women and children Dakar, Senegal, December 3, 2008

  2. Some of the research being done in Africa • HIV prevention studies • Microbiscides studies • Male circumscion and its impact on female HIV transmission • PMTCT stuudies • HIV intervention studies • Discordant couples studies • Issues on adherence • Variuos clinical trials • For adults and children

  3. Who is doing the research • Indeginous researchers • But poorly funded by local institutions • Collaborative research • Through North-South institutions • Major funding agents • Industries • On a limited scale • Their support through North instuitutions

  4. Major challenges • Poor infrastructure • Inadequate human resources • Research monitoring infrastructure • IRBs, etc. • Ethical issues • How to involve children • Issues of consent among women • Influence on policy makers

  5. Some research gaps • Appropriate interventions for children as they grow up • Impact of adolescence on ART and vice versa • Why PMTCT uptake remains low • Even when it is provided free of charge • Gender issues that influence ART adherence • Both in short term and long term

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