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U06-130 #16937856102

U06-130 #16937856102. 19 year old female Artheritis with increased creatinine, proteinuria, hematuria. ? Lupus.

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U06-130 #16937856102

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  1. U06-130#16937856102 19 year old female Artheritis with increased creatinine, proteinuria, hematuria. ? Lupus

  2. 21yrs old female   Presented with arthralgias associated with an elevated serum creatinine. Symptoms began immediately after a (second) therapeutic abortionCreatinine 189 U/A +3 protein ,WBC  26-50 ,RBC 11-25,Protein/Cr  227 mg/mmole, Albumin 19 Hb 79   plat 168 WBC 3.9Anti DNA +ANA  +C3  &    C4  Low

  3. IF • IgG- Moderate to strong coarsely granular capillary loop staining, moderate granular peritubular staining • IgA- Moderate coarsely granular capillary loop staining • IgM- Negative • C3- Moderate coarsely granular capillary loop staining, moderate granular peritubular staining • C1q- Moderate coarsely granular capillary loop staining, mild to moderate granular peritubular staining • Kappa- Mild to moderate coarsely granular capillary loop staining, mild to moderate granular peritubular staining • Lambda- Same as kappa • Fibrin- Mild to moderate interstitial staining • Albumin- Mild to moderate hyaline droplet change in tubular cytoplasm

  4. IgG

  5. IgG

  6. IgA

  7. C3

  8. C3

  9. Clq

  10. Clq

  11. Kappa

  12. Kappa

  13. Lambda

  14. Lambda

  15. Fibrin

  16. Albumin

  17. Diagnosis:Renal Biopsy:Diffuse global proliferative lupus nephritis (Class IV-G (A), 2003 ISN/RPS Classification) with moderate activity and mild chronicity.

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