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U06-130 #16937856102. 19 year old female Artheritis with increased creatinine, proteinuria, hematuria. ? Lupus.
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U06-130#16937856102 19 year old female Artheritis with increased creatinine, proteinuria, hematuria. ? Lupus
21yrs old female Presented with arthralgias associated with an elevated serum creatinine. Symptoms began immediately after a (second) therapeutic abortionCreatinine 189 U/A +3 protein ,WBC 26-50 ,RBC 11-25,Protein/Cr 227 mg/mmole, Albumin 19 Hb 79 plat 168 WBC 3.9Anti DNA +ANA +C3 & C4 Low
IF • IgG- Moderate to strong coarsely granular capillary loop staining, moderate granular peritubular staining • IgA- Moderate coarsely granular capillary loop staining • IgM- Negative • C3- Moderate coarsely granular capillary loop staining, moderate granular peritubular staining • C1q- Moderate coarsely granular capillary loop staining, mild to moderate granular peritubular staining • Kappa- Mild to moderate coarsely granular capillary loop staining, mild to moderate granular peritubular staining • Lambda- Same as kappa • Fibrin- Mild to moderate interstitial staining • Albumin- Mild to moderate hyaline droplet change in tubular cytoplasm
Diagnosis:Renal Biopsy:Diffuse global proliferative lupus nephritis (Class IV-G (A), 2003 ISN/RPS Classification) with moderate activity and mild chronicity.