Contemporary Missiology, cont d

From Evangelii Nuntiandi (1975). ?Jesus Himself, the Good News of God, was the very first and the greatest evangelizer; He was so through and through: to perfection and to the point of the sacrifice of His earthly life.To evangelize: what meaning did this imperative have for Christ? ?Let it suffice

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Ecorse Creek 1996 Toxicity Testing

Ecorse Creek 1996 Toxicity Testing. Prepared by: StreamTeam O.L.of Mt. Carmel H.S. in cooperation with the Michigan Department of Environmental Quality (MDEQ). With special contributions from : Southgate Anderson H.S. and RIverview H.S. STREAMTEAM ‘96-’97.

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Toxicity and Field Testing Apparatus

. SA Bill of Rights. 24. Environment Everyone has the right- to an environment that is not harmful to their health or well-being; and to have the environment protected, for the benefit of present and future generations, through reasonable legislative and other measures that- prevent pollution an

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Toxicity Testing in Marine Conservation

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Toxicity Testing

Cycle of Response to Toxics. Toxic effect of one substance documented. Public response/ outcry. Legislation to regulate toxic effects. More studies of other chemicalsImproved analytical accuracy. . . . . . Modern History of Toxicology. Industrial RevolutionThe Jungle, Wiley Bill1900 -

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Acute and Chronic Toxicity Testing

Acute and Chronic Toxicity Testing. Standard Methods . Multiple methods have been standardized (certified) by multiple organizations American Society for Testing and Materials (ASTM) Organization for Economic Cooperation and Materials (OECD) – (Europe based) National Toxicology Program (NTP)

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TRACEABILITY IN TOXICITY TESTING

TRACEABILITY IN TOXICITY TESTING. Beth Thompson September 20, 2011 . TRACEABILITY. COMPLETENESS OF THE INFORMATION REGARDING EVERY STEP IN A PROCESS DOCUMENTATION OF RECORDED INFORMATION’S HISTORY GENERATE REPRODUCABLE AND/OR DEFENDABLE DATA. ANALYTICAL TRACEABILITY. SAMPLE TRACKING

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HURDLES IN TOXICITY TESTING

HURDLES IN TOXICITY TESTING. Elizabeth Thompson Shealy Consulting, LLC 2013 ASP Annual Workshop . TOPICS FOR DISCUSSION. Toxicity Testing Basics Specific Challenges with Ceriodaphnia and Toxicity in General . History.

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Toxicity Testing: Nitrification Inhibition

Toxicity Testing: Nitrification Inhibition. Jessica Shaw Environmental Supervisor City of Wenatchee. City of Wenatchee. What happened? . Problems at the POTW NPDES Violations Lawsuit by Environmental Groups 1. High Strength 2. Inhibitory/Toxic Characteristics.

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Chapter 20: Toxicity Testing

Chapter 20: Toxicity Testing. Toxicity Testing. There are two purposes of toxicity testing. There is a quantitative effort to elucidate a dose–effect relationship There is a qualitative determination of the toxicity of the agent relative to other known chemicals. Toxicology testing, cont.

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Toxicity Testing

Toxicity Testing. and Environmental Risk Assessment. Dimensions of the Toxic Chemical Problem. Chemical entities 4-10 million Developed annually ~ 6000 In commerce ~ 65,000 In common use ~ 6,000 Regulated water 129 air 25 .

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Externalization/Visualization (cont ’ d)

Externalization/Visualization (cont ’ d). Visualization and Comprehension. Even when discussing numeric problems, “ seeing ” the relationship is important. Function-Generating Problems.

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Acute and Chronic Toxicity Testing

Acute and Chronic Toxicity Testing. Standard Methods. Multiple methods have been standardized (certified) by multiple organizations American Society for Testing and Materials (ASTM) Organization for Economic Cooperation and Materials (OECD) – (Europe based) National Toxicology Program (NTP)

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Toxicity Testing II P erforming a toxicity test

Toxicity Testing II P erforming a toxicity test. Toxicity testing. Acute toxicity test Short time frame exposure (96h) “kill ‘em and count ‘em” LC 50 , TLM (median tolerance limit EC 50 (effective concentration) Chronic toxicity test Longer time frame exposure (1 week to 3 years)

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Toxicity testing on animals

Toxicity testing on animals. No Observed Effect Level (NOEL) = Exposure with no adverse effects in animal models. ÷ 10. NOEL for human exposure. Data from case reports and observational studies. Risk assessment -Which adverse effect seen in animals are likely to also affect human health?

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Toxicity Testing Services

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MAIN TOXICITY TESTING

MAIN TOXICITY TESTING. TESTING STRATEGIES. A number of different types of data are used in order to establish the safety of chemical substances for use in foods. These include: Consideration of the chemical structutre and any intended biological activity (e.g. anti-oxidant)

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