1 / 8

Starting children and infants on ART; what do the guidelines say?

Starting children and infants on ART; what do the guidelines say?. Dr Siobhan Crowley Paediatric & Family HIV Care Department of HIV/AIDS World Heath Organization, Email: crowleys@who.int http://www.who.int/hiv/paediatric/en/index.html. WHO recommendations.

adanne
Download Presentation

Starting children and infants on ART; what do the guidelines say?

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Starting children and infants on ART; what do the guidelines say? Dr Siobhan Crowley Paediatric & Family HIV Care Department of HIV/AIDS World Heath Organization, Email: crowleys@who.int http://www.who.int/hiv/paediatric/en/index.html

  2. WHO recommendations • Published within adult guidelines in 2003 • Stand alone August 2006 • Include dosing instructions (Annex E) • Review meeting April 2008 http://www.who.int/hiv/pub/guidelines/art/en/index.html http://www.who.int/hiv/paediatric/generictool/en/index.html

  3. April 2008 –Technical Reference group meeting For infants panel reviewed: • When to perform virological testing • When to start ART • What ARVS to start in infants with HIV :

  4. What ART to Start in infants –2008 revision NVP triple ART No infant or maternal ARV exposure Baby 18% Mum 34% PI triple ART# Sd NVP or NNRTI containing ART MTCT ARV Exposure NVP triple ART Non NNRTI exposure Unknown infant maternal MTCT Exposure NVP triple ART # If no PI is available use NVP triple ART

  5. Children 1 year or over Clinical and/or immunological criteria to start ART Standard first line regimen NNRTI + 2NRTI < 3 years NVP + AZT + 3TC > 3 years EFV + AZT + 3TC Standard second line regimen PI + 2 new NRTI

  6. Summary

  7. Revised simplified dosing

  8. Acknowledgments & resources: • HIV Care Technical Reference group • Paediatric ARV dosing working group: • Tony Nunn, Ed Caparelli, Shaffiq Essajee, Mark Mirochnick & Diana Clarke Meeting report summarising these recommendations http://www.who.int/hiv/pub/paediatric/WHO_Paediatric_ART_guideline_rev_mreport_2008.pdf Proceedings of the meeting http://www.who.int/hiv/pub/meetingreports/art_meeting_april2008/en/index.html 2006 guidelines (being updated to reflect above) http://www.who.int/hiv/pub/guidelines/art/en/index.html Tool to assist in developing dosing recommendations http://www.who.int/hiv/paediatric/generictool/en/index.html A programming guide – how to scale up Paed care and treatment: http://www.who.int/hiv/paediatric/Paeds_programming_framework2008.pdf Paediatric HIV care landing page http://www.who.int/hiv/paediatric/en/index.html

More Related