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Anatomy of Cells

Anatomy of Cells. “Typical” Cell. “Typical” Cell vs. Reality. “Typical” cells do not actually exist in the body Cell are specialized structure to carry out specialized functions (see Table 3-1, pg. 73) Nerve cells: have long extension  transmit nerve impulses throughout the body

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Anatomy of Cells

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  1. Anatomy of Cells

  2. “Typical” Cell

  3. “Typical” Cell vs. Reality • “Typical” cells do not actually exist in the body • Cell are specialized structure to carry out specialized functions (see Table 3-1, pg. 73) • Nerve cells: have long extension  transmit nerve impulses throughout the body • Muscle cells: contain fibers that slide together  contracts/movement of body parts • RBCs: contain hemoglobin  carry oxygen from lungs to various parts of the body

  4. Main Components of Cell Structure • Plasma Membrane • Cytoplasm • Cytosol (intracellular fluid) • Organelles • Nucleus • Cytoskeleton • Cell’s internal supporting framework

  5. Plasma Membrane • Phospholipid bilayer • Hydrophilic heads • Hydrophobic tails • Majority of membrane is hydrophobic – water and water-soluble molecules cannot pass • Cholesterol – steroid lipid; provides stabilization for the plasma membrane

  6. Plasma Membrane • Embedded proteins • Penetrate into the hydrophobic regions of the plasma membrane • Transport mechanism • Transport proteins are often specific for certain molecules • “Gates” can open or close

  7. Plasma Membrane • Peripheral Proteins • Glycoproteins (carbohydrates and proteins) • Identification markers • Recognize self vs. non-self (immune system) • Receptors • Proteins that react in the presence of hormones or other regulatory chemicals • Trigger metabolic changes within the cells • Signal transduction

  8. Cytoplasm • Cytosol • Watery solution • Intercellular fluid (ICF) • Organelles • “tiny organs” • Thicken the cytosol to a gel-like consistency

  9. Endoplasmic Reticulum • Rough ER • Presence of ribosomes • Protein synthesis • Intracellular transport • Smooth ER • Lipid and carbohydrate synthesis • Replenishes cell membrane material http://micro.magnet.fsu.edu/cells/endoplasmicreticulum/images/endoplasmicreticulumfigure1.jpg

  10. Ribosomes • Attached to Rough ER or scattered throughout cytoplasm • Composed of a large and a small subunit • Each subunit contains RNA (rRNA) bonded to protein • Function – Protein synthesis • Cell’s “protein factory”

  11. Golgi Apparatus • Consists of tiny sacs or cisternea • “processing & packaging plant” • Export proteins make in the Rough ER out of the cell • Secretion • Fig 3-5, page 81

  12. Lysosomes • Vesicles that have pinched off from the Golgi apparatus • Contain enzymes capable of breaking down cell components • “digestive bags” or “cellular garbage disposals” • Ex: rid cells of bacteria; Scavenger WBCs

  13. Peroxisomes • Similar to lysosomes • Small sac containing enzymes • Important in kidney and liver cells • Detoxification functions in the body

  14. Mitochondria • Structure: • Two membranes (sac within a sac) • Inner membrane contains folds (cristae) • Function: • Enzymes embedded in cristae – essential in making adenosine tri-phosphate (ATP) • Cell “power plant” • # of mitochondria based on amt of work done by cell • Ex: liver cells > sperm cells • Self-replicating – based on energy needs • Aerobic exercise increases # of mitochondria in skeletal muscle cells

  15. Mitochondria

  16. Nucleus • Large, spherical organelle • Enclosed by a two nuclear membranes = nuclear envelope • Nuclear pores – selectively allow molecules to enter/leave nucleus • Contains DNA (genetic information) • Chromatin – uncondensed genetic material • Chromosomes – condensed genetic material • Nucleolus – synthesizes rRNA

  17. Nucleus

  18. Cytoskeleton • Cell Fibers • Microfilaments • “Cellular muscles” • Thin, twisted strains of protein • Can contract (ex: muscle cells) • Intermediate Filaments • slightly thicker • Main component of the supporting framework in many cell types • Microtubules • Thickest of the cell fibers; tiny, hollow tubes • Cell “engine” – help with movement within the cell and the cell itself

  19. Cytoskeleton • Centrosome • Located near the nucleus • “microtubule-organization center” • Important role in cell division – move chromosomes around the cell • Centrioles • Cylindrical structures within the centrosome • Replicate prior to cell division • Roles in cell division

  20. Cell Extensions • Microvilli • Epithelial cells found where absorption is necessary (ex: small intestine) • Increase surface area • Cilia • Transport fluid across a cell surface • Ex: Line the respiratory tract – move mucous upward • Ex: Assist the ovum to move towards the uterus • Flagella • Single, long structures; aids in locomotion • Ex: sperm cells

  21. Anthony’s Textbook of Anatomy and Physiology 17th Edition. Thibodeau, Gary A. PhD and Patton, Kevin T. PhD. Mosby, Inc.

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