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Exploring Patients' Experience of Antidepressant Medication Discontinuation

This presentation by Penny Louch on November 15, 2008, delves into the patient experience of stopping antidepressant medication, encompassing the global burden of depression, the personal, family, social, and economic impacts, as well as the rationale for the study, theoretical framework, study design, and research findings. The session also examines depression diagnosis in primary care and research questions focusing on patient concerns when discontinuing antidepressants. Through a mix of questionnaire responses and in-depth interviews with patients, the study uncovers varied insights on recovery, the role of antidepressants, and self-perceptions related to depression.

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Exploring Patients' Experience of Antidepressant Medication Discontinuation

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  1. Depression: The Patient Experience of Stopping Antidepressant Medication Penny Louch 15th November 2008

  2. Presentation Plan • Depression in context • Rationale for study • Theoretical framework • Study design • Findings

  3. Global Burden of Depression WHO. The World Health Report 2001. Mental Health: New Understanding, New Hope. Geneva: WHO, 2001 WHO. World Health Statistics 2006. 2006. France, WHO.

  4. European Burden of Depression WHO. The European Health Report 2002. 2002. Copenhagen, Denmark, WHO Regional Officefor Europe.

  5. 1in 3 Families Experience Depression The Burden of Depression • Personal • Family • Social • Economic • Office for National Statistics. Psychiatric Morbidity in Great Britain, 2000, Prevalence of Psychiatric Morbidity Among Adults Living in Private Households. London: HMSO, 2001. • The Centre for Economic Performance's Mental Health Policy Group. The Depression Report: New Deal for Depression and Anxiety Disorders. London: London School of Economics, 2006.

  6. Depression Diagnosis in Primary Care Rule of Halves Lepine JP, Gastpar M, Mendlewicz J, Tylee A. Depression in the community: The first pan-European study DEPRES (Depression Research in European Society). Int.Clin.Psychopharmacol. 1997;12:19-29.

  7. Rationale for the Study • Previous research • Quantitative and biomedical • Few studies about stopping antidepressants

  8. Research Questions “What is the nature of the concerns patients experience when they stop their antidepressant medication?” “Are these concerns dependent upon a personal construction of the meaning of recovery from a depressive illness?”

  9. Kleinman 5 parts of an illness experience Explanatory Model Theory Kleinman A. Patients and healers in the context of culture. Berkeley, CA: University of California Press, 1980.

  10. Study Design • General practice • Data collection • Questionnaire • Interviews

  11. Questionnaire sent to 572 patients In-depth interview with 30 patients Patients aged 18-100+ years; depression diagnosed 6/12 or more; primary care only; taking antidepressants

  12. Questionnaire

  13. Questionnaire Responses

  14. Data Analysis • Questionnaires: • QSR N6 • Qualitative data analysis computer software tool • Interviews: • Framework • Thematic approach • Data indexed and charted according to key issues and themes • NVivo

  15. Findings • A trajectory towards madness? • Depression - A chemical imbalance? • Antidepressants – friend or foe? • Self • Stopping antidepressants • Recovery

  16. Conclusions • Multiple insights • Clinician-researcher role • Interview process

  17. Thank You Email p.louch@ucl.ac.uk Website www.depression-primarycare.co.uk

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