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Cancer Care Engineering

Cancer Care Engineering. Joe Pekny, PhD Visionary Marietta Harrison, PhD Worker Bee. Cancer Care Engineering. Current Funding Initiatives. Engineering the Cancer System (R-CCE). Warfighter CCE (W-CCE). Walther Cancer Institute Foundation. Funded: $1.35M Regenstrief Institute 7/1/07-2009.

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Cancer Care Engineering

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  1. Cancer Care Engineering Joe Pekny, PhD Visionary Marietta Harrison, PhD Worker Bee

  2. Cancer Care Engineering Current Funding Initiatives Engineering the Cancer System (R-CCE) Warfighter CCE (W-CCE) Walther Cancer Institute Foundation Funded: $1.35M Regenstrief Institute 7/1/07-2009 Funded: $2.4M DOD, 12/1/07-2011 Funded: $0.2M 2007-2009 Dog-CCE (D-CCE) • Focused on Health Services Research • Cancer Care Delivery, Modeling & Data Visualization, CCEHub • Focused on Prevention, Molecular Signatures • Sample Acquisition, OMIC Analysis, Data Modeling, Data Visualization, Literature Mining Funded: $0.2M 2007-2009 Regenstrief, PCC, DP, Engineering, Vet School

  3. Cancer Care Engineering Vision: to harness goal-oriented research to solve the cancer problem using Indiana as model for the nation Approach: create an engineering “Systems Analysis” model for cancer prevention, detection, treatment and care delivery Team: Over seventy physicians, caregivers, engineers, scientists and staff drive the CCE vision

  4. CCE Milestones 9/05 9/06 5/07 7/07 4/08 10/08 3/06 11/06 6/07 3/08 6/08 11/08 WCCE-1 DOD IRB IU IRB SRC-1 IU IRB SRC-2 WCCE Proposal First NIH Proposal Initial DCCE Results Regenstrief CCE Funded Regenstrief CCE Proposal CCE is “Born” in Lebanon, IN Indy Foundations Presentation Washington WCCE Presentation

  5. Cancer Care Engineering The Integrated Pillars Mathematical Models Patient OMIC Analysis Health Services Research Cancer as a Managed Disease

  6. Cancer Care Engineering Predictive Biomarkers “OMICS” • Patient Blood • Genomic Analysis • Lipidomic • Metabolomic • Glycoproteomic

  7. Cancer Care Engineering Critical Enablers • Interactive Databases • -CCEHub • Visualization

  8. Mathematical Models • Statistical • Semi-mechanistic • Population-based • Agent-based Cancer Care Engineering

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