1 / 15

Johns Hopkins Hospital Neuro-Oncology Program: Adult Brain Tumors

Johns Hopkins Hospital Neuro-Oncology Program: Adult Brain Tumors . Adult Brain Tumors. 2 types Primary Metastatic (secondary) Patient outcome affected by: Aggressiveness of tumor Tumor location Early detection Patient age and general health Degree of surgical resection

adonia
Download Presentation

Johns Hopkins Hospital Neuro-Oncology Program: Adult Brain Tumors

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Johns Hopkins HospitalNeuro-Oncology Program:Adult Brain Tumors

  2. Adult Brain Tumors • 2 types • Primary • Metastatic (secondary) • Patient outcome affected by: • Aggressiveness of tumor • Tumor location • Early detection • Patient age and general health • Degree of surgical resection • Additional non-surgical treatments

  3. Primary Brain Tumors

  4. Primary Adult Brain Tumors • Originate within the brain • Can be benign or malignant • About 40,000 new cases each year • World Health Organization: 7 major classifications • 4 tumor types make up > 85% of all brain tumors: glioma; meningioma; schwannoma; pituitary adenoma

  5. Most Common Primary Brain Tumors

  6. Gliomas - 1 • World Health Organization uses a grading system: • Low Grade: slow growing • High Grade: make up the majority of gliomas and are very aggressive

  7. Gliomas - 2 • Most common primary brain tumor • Astrocytoma, Oligodendroglioma, Mixed glioma • Astrocytoma (Grades I-IV) • Grade I • Pilocytic; more often seen in children and young adults; does not infiltrate the brain; surgery can cure this tumor

  8. Gliomas - 3 • Grade II • Diffuse Astrocytoma; infiltrates the brain; surgery +/- radiation; may become high grade • Grade III • Anaplastic Astrocytoma; more infiltrative and causes more swelling; surgery, radiation, and chemotherapy • Grade IV • Glioblastoma Multiforme; highly infiltrative; requires aggressive treatment including surgery, radiation, chemotherapy and experimental protocols

  9. Gliomas - 4 • Oligodendroglioma (Grades II-IV) • 10-15% of gliomas • Most are grade II • Somewhat less aggressive than astrocytomas • Mixed glioma • “oligoastrocytoma” • Features of both astrocytoma and oligodendroglioma

  10. Meningiomas • Slow growing • Usually benign • Originate from covering of the brain (meninges) • Because they grow slowly, they may become quite large before causing symptoms • May be cured with surgery • Radiation can be used for residual or recurrent tumor

  11. Acoustic Neuroma(Schwannoma) • Benign • Encapsulated • Patients may complain of hearing loss or ringing in the ears • Curable with surgery • Focused radiation (radiosurgery; FSR) may be used instead of surgery, depending on tumor size and patient preference

  12. Pituitary Adenoma • Benign • May secrete hormones or may be non-secreting • Classified by size • Microadenoma < 1 cm • Macroadenoma > 1 cm • Can cause visual field problems by pushing up on the optic nerves • Some tumors can be treated with medicine (prolactinomas, for example) • Surgery: transsphenoidal (95%) or craniotomy • Radiation can be used for residual or recurrent tumor

  13. Metastatic (Secondary) Brain Tumor

  14. Metastatic Brain Tumors • Originate in other part of the body and travel to brain through the blood • Always malignant • About 160,000 new cases each year • Occur in 10-15% of cancer patients • May have solitary or multiple metastases • Surgery, radiation, +/- chemotherapy

  15. Most Common Metastatic Brain Tumors

More Related