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Nosocomial Fungal Infections and Risk Factors in Intensive Care Unit

Nosocomial Fungal Infections and Risk Factors in Intensive Care Unit. Nalan Adıgüzel, Zuhal Karakurt, Gökay Güngör, Tülay Yarkın, Eylem Acartürk, Özlem Soğukpınar SB Süreyyapaşa Chest Diseases and Thoracic Surgery Teaching Hospital, İstanbul, TÜRKİYE. Study Objectives.

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Nosocomial Fungal Infections and Risk Factors in Intensive Care Unit

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  1. Nosocomial Fungal Infections and Risk Factors in Intensive Care Unit Nalan Adıgüzel, Zuhal Karakurt, Gökay Güngör, Tülay Yarkın, Eylem Acartürk, Özlem Soğukpınar SB Süreyyapaşa Chest Diseases and Thoracic Surgery Teaching Hospital, İstanbul, TÜRKİYE

  2. Study Objectives • Although fungal infectionshave been considered as an important problem in neutropenic patients, nowadays it is increasingly diagnosed in nonneutropenic and especially in critically ill patients. • In this study, we aimed to determine nosocomial fungal infection rate and related risk factors in the respiratory intensive care unit (RICU).

  3. Materials and Method • Design: Retrospective • Setting: Respiratory Intensive Care Unit (RICU) with 10 bed in a large teaching hospital • Study Period: January - December 2006 • Patients: 163 patients who stayed in RICU ≥ 24 hours • Evaluation: Patients with and without nosocomial fungal infection were compared to each other according to demographic and clinical features

  4. Results Demografic Features

  5. Results • In 20 patients, Candida species (13 albicans, 7 nonalbicans) were cultured microbiologically at least one biologic sample. • In 6 patients, fungal infection was considered clinically and bronchoscopically. • Antifungal treatment was given in 25 patients 3-52 days (mean 19). • One patient who did not received antifungal treatment was diagnosed by blood culture after she died.

  6. Results In 20 patients, Candida species were cultured microbiologically at least one biologic sample

  7. Results Nonalbicans Candida species

  8. In 11 patients, white-mucous plaques were seen extensively on the tracheobronchial mucosa

  9. Results Comparisons of the patients with and without nosocomial fungal infections according to the clinical features

  10. Results Risk Factors for Development of Nosocomial Fungal Infections

  11. Conclusions Literatürde YBÜ’de Mantar Enfeksiyonu için Risk Faktörleri

  12. Conclusions • Fungal infections should be kept in mind as a nosocomial infection in critically ill patients who have risk factors • It should be aimed to reduce mortality rate by starting treatment earlier

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