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Asthma control test (ACT) scores and FeNO correlation

Asthma control test (ACT) scores and FeNO correlation. Yıldırım BZ, Doğan İ, S Serbest, Güven K, Gemicioğlu B. Aim. To evaluate the correlation of ACT and FeNO in asthma control in asthmatics. GINA 2006 and Consept of Control. Asthma Control Test (ACT).

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Asthma control test (ACT) scores and FeNO correlation

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  1. Asthma control test (ACT) scores and FeNO correlation Yıldırım BZ, Doğan İ, S Serbest, Güven K, Gemicioğlu B.

  2. Aim • To evaluate the correlation of ACT and FeNO in asthma control in asthmatics

  3. GINA 2006 and Consept of Control

  4. Asthma Control Test (ACT) • ACT is a validated, practical instrument to evaluate asthma control • ACT measures the quality of asthma control objectively by using simple numerical values as the target of treatment • It is reliable, valid and sensitive to fluctuations in asthma control over time

  5. FeNO • NO is a noninvasive marker of inflammation • It reveals the eosinophilic inflammation and response to corticosteroids in asthmatic patients.

  6. Evaluation of FeNO in Patients Receiving Antiinflamatory Treatment Kharitonov et al., Eur Respir J 2003 21:433-8

  7. Method • ACT, pulmonary functions and FeNO were measured in 71 cases who were diagnosed as persistent asthma and were receiving combined therapy

  8. Epidemiological and Functional Characteristics of Our Cases

  9. Findings

  10. Mean ACT Scores

  11. Mean FeNO

  12. ACT-FeNO

  13. ACT-FEV1

  14. FEV1-FeNO

  15. ACT-FeNO • ACT scores were found to be negatively correlated with FeNO (by using Pearson correlation test r=-0,342; p=0,004).

  16. ACT-FeNO Correlation

  17. Conclusions • ACT and NO are negatively correlated • In patients whose ACT scores mean controlled, anti-inflammatory therapy yet may be insufficient. • ACT is useful in symptomatic and functional follow-up in asthmatic patients but may not be sufficient in evaluating the inflammation

  18. Conclusions • Routine NO measurement combined with ACT may be helpful in adjusting the antiinflammatory treatment in patients who are considered controlled according to ACT only

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